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    North Charleston, SC Medical Office Space for Lease

    9 results
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    Former Daycare Near Navy Yard
    $14 SF/Yr

    Former Daycare Near Navy Yard

    1910 Mcmillan Ave, North Charleston, SC 29405

    12,895 SF former daycare near new Navy Yard.

    • Located just outside the new Navy Yard redevelopment project (retail, office, residential, mixed‑use).
    • ±12,895 SF former daycare suitable for daycare/preschool, medical/professional office, church, or financial service institution.
    • $546k of New FF&E and Tenant Improvements since 2022, including a new roof and 3 replaced HVAC Units (9 total).
    • Occupancy for 300 Total Children.
    • Proximity to the Lowcountry Rapid Transit System (coming in 2026).
    View details
    North Charleston Office Space Available
    $19 SF/Yr
    1,664 SF

    North Charleston Office Space Available

    2070 Northbrook Blvd, North Charleston, SC

    Office space for rent in North Rivers Business Center.

    • High Occupancy Rate (98%) indicating strong tenant demand and income stability
    • Diverse Tenant Mix including medical, government, and professional office users
    • Presence of well‑known tenants such as MUSC Children's Health Clinic and Roper St. Francis ATI
    • Strategic Location with accessibility from Rivers Avenue and Northbrook Blvd
    • Includes two buildings totaling 79,611 SF
    Updated: Oct 29, 2025
    View details
    Class A Medical Office Space
    Contact for pricing
    9,806 SF

    Class A Medical Office Space

    Premier medical office space near Roper St. Francis Hospital.

    4600 Goer Dr, North Charleston, SC 29406
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    Medical/Professional Office Suite For Rent
    Contact for pricing
    1,830 SF

    Medical/Professional Office Suite For Rent

    1,830 SF medical/professional office suite near Trident Hospital Campus.

    2831 Tricom St, North Charleston, SC 29406
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    North Charleston Office Space Available
    Contact for pricing
    903 SF

    North Charleston Office Space Available

    Professional office space for lease in North Charleston, SC.

    8700 North Northpark Blvd, North Charleston, SC
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    Prime North Charleston Office Space
    $19 SF/Yr
    6,000 SF

    Prime North Charleston Office Space

    6,000 SF Office, High Visibility

    7880 Dorchester Rd, North Charleston, SC 29418
    View details
    International Blvd Office Space
    $26 SF/Yr
    7,440 SF

    International Blvd Office Space

    7,440 SF Office Suite Available

    5264 International Blvd, North Charleston, SC 29418
    View details
    Aviation Business Park Office Suite
    $19 SF/Yr
    32,456 SF

    Aviation Business Park Office Suite

    North Charleston, SC Office Space - 6,433 SF

    5965 Core Rd, North Charleston, SC 29406
    View details
    Northwoods Mall Office Space
    Contact for pricing
    748,273 SF

    Northwoods Mall Office Space

    Prime North Charleston Office Suites Available

    2150 Northwoods Blvd, North Charleston, SC 29406
    View details
    Based on your search, we've compiled 20 Potential Opportunities for your consideration. Besides 9 Active listings in North Charleston, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 7 Properties for Sales.

    Explore Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    West Ashley Medical Office Sublease
    $32 SF/Yr
    1,375 SF

    West Ashley Medical Office Sublease

    3,746 SF medical office space available for immediate sublease.

    2270 Ashley Crossing Ln, Charleston, SC 29414
    View details
    Charleston Medical Office Suite
    $32 SF/Yr
    3,746 SF

    Charleston Medical Office Suite

    Prime Medical Office Space, West Ashley

    2270 Ashley Crossing Dr, Charleston, SC 29414
    View details
    Medical/Professional Office Space Available
    Contact for pricing
    4,211 SF

    Medical/Professional Office Space Available

    Single-story office space ready for upfits near new developments.

    2947 Maybank Hwy, Johns Island, SC 29455
    View details
    Live Oak Square Medical Office Space
    $28 SF/Yr
    1,885 SF

    Live Oak Square Medical Office Space

    Johns Island, SC: Modern Medical Office Suite

    1814 Crowne Commons Way, Johns Island, SC 29455
    View details

    Explore Similar Spaces for Sale in North Charleston, SC

    Consider Similar Space for Sale. We found 7 Spaces in Nearby Locations matching your search parameters.

    Renovated Office Building Near I-26
    Contact for pricing
    71,711 SF

    Renovated Office Building Near I-26

    71,354 SF office building with recent $2M renovation.

    4975 Lacross Rd, North Charleston, SC 29406
    View details
    Former Daycare Near Navy Yard
    $2,300,000

    Former Daycare Near Navy Yard

    12,895 SF former daycare near new Navy Yard project.

    1910 Mcmillan Ave, North Charleston, SC 29405
    View details
    Dorchester Road Office Space Available
    Contact for pricing
    6,600 SF

    Dorchester Road Office Space Available

    High-traffic location with flexible spaces for professional uses.

    7880-7890 Dorchester Rd, North Charleston, SC
    View details
    Ashley Office Park: Value-Add Opportunity
    $5,250,000
    32,260 SF

    Ashley Office Park: Value-Add Opportunity

    Charleston, SC Office Park - High Occupancy

    2185 Ashley Phosphate Rd, North Charleston, SC 29406
    View details
    Prime Dorchester Rd Office Building
    $1,475,000
    6,000 SF

    Prime Dorchester Rd Office Building

    6,000 SF Office, High Traffic Location

    7880 Dorchester Rd, North Charleston, SC 29418
    View details
    North Charleston Retail/Medical Office
    $649,000
    2,000 SF

    North Charleston Retail/Medical Office

    2,000 SF Vacant Office Space, $649,000

    5401 Netherby Ln, North Charleston, SC 29420
    View details

    North Charleston, SC Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in North Charleston, SC with 16 listings featured on our commercial real estate exchange. The current inventory includes 2,071,713,600 square feet of properties with an estimated lease value of $83 SF/Yr.

    Estimated lease rates for Medical Office Space in North Charleston, SC begin at $19 SF/Yr, with an average of $20 SF/Yr and extend to $26 SF/Yr.
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    Browse Medical Office Space for Lease Near North Charleston, SC

    Popular Searches in North Charleston, SC

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    Most Searched ZIP Codes in North Charleston, SC

    • 29406
    • 29418
    • 29405
    • 29420

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