Medical Premises

Port Isabel, TX Medical Office Space for Sale

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Freestanding Office Building
Updated: Jul 23
Freestanding Office Building

505 E Highway 100, Port Isabel, TX 78578

$599,000
3,080 sqft 0.11 AC lot
0.11‑acre lot at 505 E Highway 100, Port Isabel, TX 78578
Built in 1996
Directly on Highway 100 for visibility and straightforward access
Zoning C
Flexible layout supporting office, retail, and service‑based businesses
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This listing looks promising.

Here's a quick look at some key insights for

505 E Highway 100, Port Isabel, TX 78578

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Based on your search, we've compiled 9 Potential Opportunities for your consideration. Besides 1 Active listings in Port Isabel, TX, we suggest exploring several alternatives: 4 properties in Nearby Cities, plus 4 Land Listings that present a potential for development.

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Prominent Medical Office Building
Prominent Medical Office Building

1720 Treasure Hills Blvd, Harlingen, TX 78550

Contact for pricing
9,094 sqft 1.80 AC lot

Medical-focused office building with covered patient drop-off and room to expand in Harlingen’s medical district.

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Class A Medical Office Building
Class A Medical Office Building

5700 N Expressway, Brownsville, TX 78526

Contact for pricing
66,875 sqft

Class A medical office building in a growing market.

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Three-Unit Medical Office Building
Three-Unit Medical Office Building

2401 N. Ed Carey Drive, Harlingen, TX 78550

Contact for pricing
7,586 sqft

Three one-story medical office buildings offer space for up to four tenants, including two vacant suites.

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Medical Office in Medical Plaza
Medical Office in Medical Plaza

1092 LOS EBANOS BLVD., Brownsville, TX 78520

Contact for pricing

Medical office suite with a spacious lobby, patient rooms, and private covered parking behind the building.

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Prime Commercial Lot in McAllen
Prime Commercial Lot in McAllen

4029 Expressway 83, Mcallen, TX 78501

$1,300,000
0.95 AC lot

Vacant commercial lot with high visibility and traffic exposure.

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Development Land at Major Intersection
Development Land at Major Intersection

6801 Saratoga, Corpus Christi, TX 78414

$6,250,000
15.48 AC lot

For sale development land at the Airline Road and Saratoga Boulevard intersection with utilities available nearby.

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Prime Commercial Lot Available
Prime Commercial Lot Available

7151 Williams DR, Corpus Christi, TX 78412

$1,945,000
3.00 AC lot

Over 3-acre commercial lot at a busy intersection.

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Land
Land

2778 FM 236, Victoria, TX 77905

$419,885
5.93 AC lot

Commercial land · 5.93 Acres

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Port Isabel, TX Medical Office Space Market Trends and Statistics

Explore 1 medical office space for sale in Port Isabel, TX on our real estate platform. These investment opportunities span a total of 3,080 square feet of properties for sale, with an estimated market value of $599,000.

Sale prices for medical spaces in Port Isabel, TX average $599,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Top Commercial Asset Segments

Commercial property segments ranked by active listings on the market

Medical Office Space 1
Office buildings 1

Demographics Overview

Population 10K
Population Growth (5Y) -12.4%
Median Household Income $52,041
College Educated 34.6%

High-Yield Neighborhoods for Investment

Identify Port Isabel submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood Average Price
78578 $599K

Taxes & Financing

Tax Rate (average for all types) 1.71%
Property Tax per SF $20.64 per SF
Tax Rate vs County Average 0.10 pp below county avg
Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in Cameron County

New Delisted

Total CRE Inventory on Market (SF)

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