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Port Isabel, TX

Port Isabel, TX Commercial Real Estate for Sale

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South Padre Island, TX Laguna Heights, TX Laguna Vista, TX

6 properties

Highway 100 Commercial Opportunity

Updated: Jun 22, 2025

Highway 100 Commercial Opportunity

321 Highway 100, Port Isabel, TX 78578

$1,500,000

2,384 sqft · 1.00 AC lot

Prime commercial location on Highway 100 in Port Isabel, a high‑traffic area.
Turnkey business opportunity including building, equipment, inventory, and business operation.
Two businesses included: a convenience store (1,224 sq ft) and a liquor store (1,160 sq ft).
Well‑established business with a 40+ year operating history.
Drive‑through window at the liquor store for customer convenience.

Waterfront Multi-Use Income Property

Updated: Mar 21

Waterfront Multi-Use Income Property

418 W Highway 100, Port Isabel, TX 78578

$9,000,000

25,257 sqft · 4.47 AC lot

High income‑producing multi‑use waterfront asset with diversified income streams.
Significant revenue growth (over 50% year‑over‑year) driven by recent upgrades and improved management.
Strong NET income and immediate cash flow.
Additional land available for future development.
Includes 13 fully occupied apartments and 24 hotel rooms.

Commercial Lot in Port Isabel

Commercial Lot in Port Isabel

Highway 100 lot: 3, Port Isabel, TX 78578

$325,000

0.16 AC lot

Commercial lot available in the center of Port Isabel, Texas.

Turn Any Listing Into an Investment Snapshot Owner equity, real caprate, demand score for every listing. Go To Analytics Center

Waterfront Lot with Dock

Waterfront Lot with Dock

106 Isabella Point Dr. lot: 49, Port Isabel, TX 78578

$230,000

0.07 AC lot

Waterfront lot with dock, boat slip, and boat lift.

Waterfront Development Opportunity in Port Isabel

Waterfront Development Opportunity in Port Isabel

100 Port Rd, Port Isabel, TX 78578

$13,900,000

27.70 AC lot

27.7 acres with 3,260 feet of waterfront near South Padre.

Port Isabel Retail Lot For Sale

Port Isabel Retail Lot For Sale

1504 W Highway 100 - Lot 2, Port Isabel, TX 78578

$1,100,000

1.68 AC lot

1.68 acre retail lot near South Padre Island.

Based on your search, we've compiled 76 Potential Opportunities for your consideration. Besides 6 Active listings in Port Isabel, TX, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 66 Off-Market properties to explore as potential leads

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Commercial Land Parcel with Five Lots

Commercial Land Parcel with Five Lots

47632 Highway 100 lot: 1-5, Laguna Heights, TX 78578

$900,000

0.70 AC lot

Vacant commercial land with five contiguous lots along Highway 100, offering flexible options for future development.

Laguna Vista Commercial Land

Laguna Vista Commercial Land

FM 510 lot: 0, Laguna Vista, TX 78578

$800,000

3.17 AC lot

Commercial land with FM510 frontage, residential use possible.

South Padre Island Commercial Lots

South Padre Island Commercial Lots

Padre Blvd. lot: 1&2, South Padre Island, TX 78597

$525,000

0.44 AC lot

Two commercial lots on Padre Blvd in South Padre Island.

Commercial Corner Land Opportunity

Commercial Corner Land Opportunity

5-6-5407 Padre Blvd, South Padre Island, TX 78597

$495,000

Two combined corner lots offer flexible commercial development options for buyers evaluating zoning opportunities.

Off-Market Properties in Port Isabel, TX

Consider similar Off-Market properties in Port Isabel, TX. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

COMMERCIAL (GENERAL)

600 Davis St, Port Isabel, TX 78578-4605

$500,000

Estimated value

3,000 sqft · 0.49 AC lot

702 Champion Ave

COMMERCIAL (GENERAL)

702 Champion Ave, Port Isabel, TX 78578-2901

$1,110,000

Estimated value

6,750 sqft · 0.10 AC lot

1673 State Hwy 100

COMMERCIAL (GENERAL)

1673 State Hwy 100, Port Isabel, TX 78578-2806

$2,135,000

Estimated value

14,991 sqft · 1.37 AC lot

1618 State Hwy 100

COMMERCIAL (GENERAL)

1618 State Hwy 100, Port Isabel, TX 78578

Value Estimation by Request

2,574 sqft · 0.78 AC lot

VACANT COMMERCIAL LAND

511 Ws Shr Dr, Port Isabel, TX 78578

Value Estimation by Request

0.08 AC lot

COMMERCIAL (GENERAL)

202 2nd St, Port Isabel, TX 78578-4100

$520,000

Estimated value

3,162 sqft · 2.10 AC lot

COMMERCIAL (GENERAL)

803 Shr Drw, Port Isabel, TX 78578-0135

Value Estimation by Request

483 sqft · 0.23 AC lot

COMMERCIAL (GENERAL)

Garcia, Port Isabel, TX 78578

Value Estimation by Request

2.56 AC lot

414 Queen Isabella

COMMERCIAL (GENERAL)

414 Queen Isabella, Port Isabel, TX 78578-2411

Value Estimation by Request

3,500 sqft · 0.14 AC lot

203 Queen Isabella

COMMERCIAL (GENERAL)

203 Queen Isabella, Port Isabel, TX 78578-2418

Value Estimation by Request

1,080 sqft · 0.04 AC lot

COMMERCIAL (GENERAL)

810 Garcia St, Port Isabel, TX 78578-4034

Value Estimation by Request

2,232 sqft · 0.34 AC lot

VACANT COMMERCIAL LAND

Polk St, Port Isabel, TX 78578

Value Estimation by Request

0.14 AC lot

COMMERCIAL (GENERAL)

401 Maxan St, Port Isabel, TX 78578-4521

$825,000

Estimated value

7,900 sqft · 0.14 AC lot

1106 State Hwy 100

COMMERCIAL (GENERAL)

1106 State Hwy 100, Port Isabel, TX 78578-2437

Value Estimation by Request

1,410 sqft · 2.93 AC lot

VACANT COMMERCIAL LAND

Country Clb, Port Isabel, TX 78578

Value Estimation by Request

0.42 AC lot

418 State Hwy 100

COMMERCIAL (GENERAL)

418 State Hwy 100, Port Isabel, TX 78578-0077

$860,000

Estimated value

5,600 sqft · 2.10 AC lot

COMMERCIAL (GENERAL)

817 Polk St, Port Isabel, TX 78578-4623

Value Estimation by Request

0.21 AC lot

VACANT COMMERCIAL LAND

Polk St, Port Isabel, TX 78578

Value Estimation by Request

0.14 AC lot

Port Isabel, TX Commercial Real Estate Market Trends and Statistics

Explore 72 commercial real estate for sale in Port Isabel, TX, showcased through 6 active listings on our real estate platform. These investment opportunities span a total of 27,641 square feet of properties for sale, with an estimated market value of $10,500,000.

Sale prices for business properties in Port Isabel, TX start at $1,500,000, averaging $5,250,000, and reaching up to $9,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Demographics Overview

Population 10K

Population Growth (5Y) -12.4%

Median Household Income $52,041

College Educated 34.6%

High-Yield Neighborhoods for Investment

Identify Port Isabel submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood	Average Price
78578	$4.3M

Taxes & Financing

Tax Rate (average for all types) 1.71%

Property Tax per SF $20.64 per SF

Tax Rate vs County Average 0.10 pp below county avg

Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in Cameron County

New Delisted

Total CRE Inventory on Market (SF)

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