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    Port Isabel, TX

    Port Isabel, TX Commercial Real Estate for Sale

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    Highway Office Building
    Updated: Jul 23
    Highway Office Building

    505 E Highway 100, Port Isabel, TX 78578

    $598,999
    3,080 sqft 0.11 AC lot
    Office building on a 0.11‑acre site
    Directly located on Highway 100
    C zoning
    Built in 1996
    505 E Highway 100, Port Isabel, TX 78578
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    This listing looks promising.

    Here's a quick look at some key insights for

    505 E Highway 100, Port Isabel, TX 78578

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    • Est. Cap Rate

      6.2%
      Above avg (5.9%)

    • Est. NOI

      $37K
      Annual

    • Price @ 7% Cap

      $530K
      Suggested

    • Property Type

      Commercial (General)
      Built 2010
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    Two-Business Convenience Store Property
    Updated: Jun 22, 2025
    Two-Business Convenience Store Property

    321 Highway 100, Port Isabel, TX 78578

    $1,500,000
    2,384 sqft 1.00 AC lot
    Two businesses included: a convenience store and a liquor store
    1,224‑square‑foot convenience store and 1,160‑square‑foot liquor store
    Drive‑through window at the liquor store
    Shared paved parking lot included
    Approximately 1 acre on Highway 100 in Port Isabel
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    Waterfront Mixed-Use Hospitality Property
    Waterfront Mixed-Use Hospitality Property

    418 W Highway 100, Port Isabel, TX 78578

    $9,000,000
    25,257 sqft 4.47 AC lot

    Waterfront asset combining lodging, apartments, marina services, dining, and RV and boat storage.

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    Waterfront Marina Property
    Waterfront Marina Property

    510 E Queen Isabella, Port Isabel, TX 78578

    $3,600,000
    810 sqft

    Office, retail space, private docks, and tour equipment support an operating coastal excursion business.

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    Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center
    Waterfront Marina Property
    Waterfront Marina Property

    510 E Queen Isabella Blvd., Port Isabel, TX 78578

    $3,600,000
    810 sqft 0.36 AC lot

    Includes a waterfront office and retail area, private docks, tour equipment, and on-site parking for visitor access.

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    Commercial Land Parcel
    Commercial Land Parcel

    Highway 100 lot: 3, Port Isabel, TX 78578

    $325,000
    0.16 AC lot

    Comm zoning and cable availability are documented for this Highway 100 commercial lot.

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    Waterfront Land with Deep-Water Access
    Waterfront Land with Deep-Water Access

    South Shore lot: 1, Port Isabel, TX 78578

    $1,220,750
    1.01 AC lot

    C-zoned waterfront parcel with access to the Intracoastal Waterway and nearby coastal waterways.

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    Waterfront Hotel, Marina and Rentals
    Waterfront Hotel, Marina and Rentals

    418 W Highway 100, Port Isabel, TX 78578

    $9,000,000
    25,257 sqft

    Multi-use waterfront property with 24 hotel rooms, 13 fully occupied apartments, 28 boat slips, and on-site dining and marine services.

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    Restaurant Redevelopment Land
    Restaurant Redevelopment Land

    313 E MAXAN ST, Port Isabel, TX 78578

    $900,000
    2,457 sqft 0.41 AC lot

    Former restaurant building on six commercial city lots, with B2 zoning for restaurant use and options for parking or expansion.

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    Intracoastal Waterfront Land
    Intracoastal Waterfront Land

    16-18-0 S Shore Dr, Port Isabel, TX 78578

    $1,185,000

    Three adjoining lots provide waterfront land along the Intracoastal Waterway with commercial or residential use potential.

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    Waterfront Land with Boat Slips
    Waterfront Land with Boat Slips

    3-1210 Bass Ave, Port Isabel, TX 78578

    $265,000

    Fenced waterfront site with utility connections available and rented boat slips providing ongoing income.

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    Waterfront Development Opportunity in Port Isabel
    Waterfront Development Opportunity in Port Isabel

    100 Port Rd, Port Isabel, TX 78578

    Contact for pricing
    27.70 AC lot

    27.7 acres with 3,260 feet of waterfront near South Padre.

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    Port Isabel Retail Lot For Sale
    Port Isabel Retail Lot For Sale

    1504 W Highway 100 - Lot 2, Port Isabel, TX 78578

    Contact for pricing
    1.68 AC lot

    1.68 acre retail lot near South Padre Island.

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    Based on your search, we've compiled 76 Potential Opportunities for your consideration. Besides 13 Active listings in Port Isabel, TX, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 59 Off-Market properties to explore as potential leads

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Five-Lot Commercial Land
    Five-Lot Commercial Land

    47632 Highway 100 lot: 1-5, Laguna Heights, TX 78578

    $900,000
    0.70 AC lot

    Vacant commercial land with C zoning and water available.

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    Corner Commercial Land
    Corner Commercial Land

    Padre Blvd. lot: 1&2, South Padre Island, TX 78597

    $525,000
    0.44 AC lot

    Two commercial lots are offered together with COM zoning and cable availability.

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    Commercial Corner Land Opportunity
    Commercial Corner Land Opportunity

    5-6-5407 Padre Blvd, South Padre Island, TX 78597

    $495,000

    Two combined corner lots offer flexible commercial development options for buyers evaluating zoning opportunities.

    View details
    Bayfront Land
    Bayfront Land

    260 Padre Blvd. lot: 0, South Padre Island, TX 78597

    $1,500,000

    Commercially zoned bayfront land with wetlands and Corps of Engineers permitting requirements for development.

    View details

    Off-Market Properties in Port Isabel, TX

    Consider similar Off-Market properties in Port Isabel, TX. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    600 Davis St
    COMMERCIAL (GENERAL)

    600 Davis St, Port Isabel, TX 78578-4605

    $335,000
    Estimated value
    3,000 sqft 0.49 AC lot
    View details
    702 Champion Ave
    COMMERCIAL (GENERAL)

    702 Champion Ave, Port Isabel, TX 78578-2901

    $1,110,000
    Estimated value
    6,750 sqft 0.10 AC lot
    View details
    1673 State Hwy 100
    COMMERCIAL (GENERAL)

    1673 State Hwy 100, Port Isabel, TX 78578-2806

    $2,135,000
    Estimated value
    14,991 sqft 1.37 AC lot
    View details
    1618 State Hwy 100
    COMMERCIAL (GENERAL)

    1618 State Hwy 100, Port Isabel, TX 78578

    $360,000
    Estimated value
    2,574 sqft 0.78 AC lot
    View details
    511 Ws Shr Dr
    VACANT COMMERCIAL LAND

    511 Ws Shr Dr, Port Isabel, TX 78578

    $240,000
    Estimated value
    0.08 AC lot
    View details
    202 2nd St
    COMMERCIAL (GENERAL)

    202 2nd St, Port Isabel, TX 78578-4100

    $360,000
    Estimated value
    3,162 sqft 2.10 AC lot
    View details
    803 Shr Drw
    COMMERCIAL (GENERAL)

    803 Shr Drw, Port Isabel, TX 78578-0135

    $90,000
    Estimated value
    483 sqft 0.23 AC lot
    View details
    Garcia
    COMMERCIAL (GENERAL)

    Garcia, Port Isabel, TX 78578

    $260,000
    Estimated value
    2.56 AC lot
    View details
    414 Queen Isabella
    COMMERCIAL (GENERAL)

    414 Queen Isabella, Port Isabel, TX 78578-2411

    $320,000
    Estimated value
    3,500 sqft 0.14 AC lot
    View details
    203 Queen Isabella
    COMMERCIAL (GENERAL)

    203 Queen Isabella, Port Isabel, TX 78578-2418

    $185,000
    Estimated value
    1,080 sqft 0.04 AC lot
    View details
    810 Garcia St
    COMMERCIAL (GENERAL)

    810 Garcia St, Port Isabel, TX 78578-4034

    $295,000
    Estimated value
    2,232 sqft 0.34 AC lot
    View details

    Port Isabel, TX Commercial Real Estate Market Trends and Statistics

    Explore 72 commercial real estate for sale in Port Isabel, TX, showcased through 13 active listings on our real estate platform. These investment opportunities span a total of 60,055 square feet of properties for sale, with an estimated market value of $31,194,749.

    Sale prices for business properties in Port Isabel, TX start at $265,000, averaging $2,835,886, and reaching up to $9,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Demographics Overview

    Population 10K
    Population Growth (5Y) -12.4%
    Median Household Income $52,041
    College Educated 34.6%

    High-Yield Neighborhoods for Investment

    Identify Port Isabel submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    78578 $3.6M

    Taxes & Financing

    Tax Rate (average for all types) 1.71%
    Property Tax per SF $20.64 per SF
    Tax Rate vs County Average 0.10 pp below county avg
    Average Loan-to-Value 65.0%

    Listings Trend

    New vs delisted commercial listings in Cameron County

    New Delisted

    Total CRE Inventory on Market (SF)

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