South Dakota Medical Office Space for sale

Updated: Sep 25

Office Building with Walkout Lower Level

1737 S Cleveland Ave, Sioux Falls, SD 57103

$1,150,000

6,284 sqft 0.53 AC lot

6,284‑square‑foot office building on 0.5345 acres
Built in 1998, with a main level and walkout basement
Main floor includes private offices, open areas, kitchenette and three restrooms
Basement has separate exterior access, private offices, a large open area and two bathrooms
On‑site parking in two lots; lower level provides access to the second lot

View details

Updated: Aug 31

Medical Office Building

108 W 4th St, Dell Rapids, SD 57022

$925,000

5,670 sqft 0.41 AC lot

2,840‑square‑foot upper level
1,460‑square‑foot lower‑level office area
Separate access for the lower level
Lower level leased year to year
B‑2 zoning on 0.4132 acres

View details

Renovated Medical Office Space

747 Ames Ave, Spearfish, SD 57783

$998,500

2,400 sqft

The facility accommodates a chiropractic practice and spa with multiple offices and two bathrooms.

View details

Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center

Medical Office with Attached Garage

1116 S County Rd, Freeman, SD 57029

$250,000

2,204 sqft 1.50 AC lot

A separate residential-style area includes a kitchen, full bath, laundry, and a bedroom currently used as an office.

View details

Office Building with Monument Signage

3800 S Kiwanis Ave, Sioux Falls, SD 57105

Contact for pricing

10,572 sqft

Corner office property with access from both streets, monument signage, lawn irrigation, and an enclosed dumpster area.

View details

Medical Office Building

108 W FOURTH ST, Dell Rapids, SD 57022

Contact for pricing

5,670 sqft

B-2 General Business zoning supports professional office use with a separately configured leased office level.

View details

Medical Office Building with Flexible Layout

725 N Lacrosse Street, Rapid City, SD 57701

$2,499,000

24,344 sqft

Two entrances and separate service areas support medical, administrative, and multi-tenant office configurations.

View details

Medical and Daycare Office Building

4800 N 4th Ave, Sioux Falls, SD 57104

Contact for pricing

49,424 sqft

Freestanding building currently laid out for daycare with wet sprinkler system, heat pumps, and parking for 104 vehicles.

View details

High-End Dakota Dunes Office Space

211 Sioux Point Rd, Dakota Dunes, SD 57049

Contact for pricing

1.73 AC lot

Professionally managed office space in a prime business district.

View details

Dakota Dunes Office Condo

383 W Steamboat Dr, Dakota Dunes, SD 57049

Contact for pricing

2,800 sqft

2,800 SF office condo, currently a dental office.

View details

Based on your search, we've compiled 72 Potential Opportunities for your consideration. Besides 10 Active listings in South Dakota, we suggest exploring several alternatives: similar 62 Off-Market properties to explore as potential leads

Off-Market Properties in South Dakota

Consider similar Off-Market properties in South Dakota. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

MEDICAL BUILDING

6301 41st St, Sioux Falls, SD 57106-1217

Estimated value:

$2,000,000

3,108 sqft 0.35 AC lot

View details

DENTAL BUILDING

101 37th St, Sioux Falls, SD 57105-5701

Estimated value:

$440,000

11,259 sqft 1.60 AC lot

View details

DENTAL BUILDING

2600 Western Ave, Sioux Falls, SD 57105-4429

Estimated value:

$490,000

2,948 sqft 0.23 AC lot

View details

DENTAL BUILDING

2301 Lorraine Pl, Sioux Falls, SD 57106-3642

Estimated value:

$320,000

1.66 AC lot

View details

MEDICAL BUILDING

809 Belfast St, Yankton, SD 57078-3324

Estimated value:

$335,000

2,482 sqft 0.30 AC lot

View details

DENTAL BUILDING

1700 Southeastern Ave, Sioux Falls, SD 57103-3227

Estimated value:

$610,000

12,664 sqft 1.65 AC lot

View details

MEDICAL BUILDING

2001 Broadway Ave, Yankton, SD 57078-2032

Estimated value:

$310,000

2,000 sqft 0.23 AC lot

View details

DENTAL BUILDING

2300 Westlake Dr, Sioux Falls, SD 57106-8527

Estimated value:

$455,000

10,612 sqft 1.05 AC lot

View details

MEDICAL BUILDING

3805 Kiwanis Cir, Sioux Falls, SD 57105-4266

Estimated value:

$995,000

4,686 sqft 0.69 AC lot

View details

DENTAL BUILDING

1710 Southeastern Ave, Sioux Falls, SD 57103-3381

Estimated value:

$885,000

3,929 sqft 0.45 AC lot

View details

MEDICAL BUILDING

920 Broadway Ave, Yankton, SD 57078-3532

Estimated value:

$1,125,000

25,256 sqft 1.09 AC lot

View details

DENTAL BUILDING

2521 Western Ave, Sioux Falls, SD 57105-3430

Estimated value:

$290,000

2,146 sqft 0.14 AC lot

View details

DENTAL BUILDING

4001 Southeastern Ave, Sioux Falls, SD 57103-5305

Estimated value:

$280,000

3,236 sqft 0.54 AC lot

View details

DENTAL BUILDING

Sioux Falls, SD 57106

Estimated value:

$205,000

8.27 AC lot

View details

South Dakota Medical Office Space Market Trends and Statistics

Explore 72 medical office space for sale in South Dakota, showcased through 10 active listings on our real estate platform. These investment opportunities span a total of 109,368 square feet of properties for sale, with an estimated market value of $5,822,500.

Sale prices for medical spaces in South Dakota start at $250,000, averaging $1,164,500, and reaching up to $2,499,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.