Add Listing
    South Dakota
    For Sale
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Property Types
    1
    • Retail
    • Office
    • Residential Income
    • Restaurants
    • Industrial
    • Mixed-Use
    • Hospitality
    • Health Care
    • Sports & Entertainment
    • Land
    • Agricultural
    • Specialty
    Price
    Price
    $
    $

    South Dakota Mixed-use Properties for Sale

    Notify Me
    List
    Map
    Sioux Falls, SD Aberdeen, SD Rapid City, SD
    31 results
    Three-Space Mixed-Use Building
    $129,900
    5,420 SF

    Three-Space Mixed-Use Building

    118 S Dakota Ave, Ree Heights, SD 57345

    Three separate spaces with bar/restaurant, retail, and unfinished area plus an included vacant lot for expansion.

    • Three separate business spaces in one building in Ree Heights, SD—bar/restaurant space, retail unit, and a third unfinished space
    • Unfinished third space offers room for offices, a headquarters, or other concepts you can design
    • Vacant lot included to the north for potential expansion, additional parking, or future development
    • Central heating and central air conditioning
    • Metal and rubber roofing with frame construction
    Updated: Apr 1
    View details
    Modern Mixed-Use Commercial Building
    $500,000
    10,080 SF

    Modern Mixed-Use Commercial Building

    508 Dakota Ave S, Wessington Springs, SD 57382

    10,080 SF mixed-use building suitable for various commercial concepts.

    • Modern commercial building constructed in 2015.
    • 10,080 square feet of interior space suitable for various commercial and mixed‑use concepts.
    • Banquet and event space nearly ready for immediate revenue generation.
    • Front portion previously operated as a bar/restaurant with significant upside potential.
    • Layout supports both immediate use and value‑add repositioning.
    Updated: Dec 15, 2025
    View details
    Renovated Commercial Property in Mobridge
    $525,000
    5,360 SF

    Renovated Commercial Property in Mobridge

    5,360 sq ft commercial property, renovated, multi-tenant potential.

    1710 E Grand, Mobridge, SD 57601
    View details
    Huron Commercial Opportunity For Sale
    $450,000
    10,050 SF

    Huron Commercial Opportunity For Sale

    10,050 sq ft commercial building in the heart of Huron.

    373-377 Wisconsin Ave SW, Huron, SD 57350
    View details
    Ipswich Commercial Property For Sale
    $594,000
    4,000 SF

    Ipswich Commercial Property For Sale

    Corner-lot property with multiple buildings, ideal for retail or industrial.

    19 5th Avenue, Ipswich, SD 57451
    View details
    Mixed-Use Property in Custer, SD
    $295,000
    3,888 SF

    Mixed-Use Property in Custer, SD

    Versatile mixed-use property with retail, warehouse, and living spaces.

    715 Mt. Rushmore Road, Custer, SD 57730
    View details
    Established Restaurant, Bar & Residence
    $400,000
    6,416 SF

    Established Restaurant, Bar & Residence

    Restaurant, bar, event venue, and residence in Orient, South Dakota.

    108 Main Street, Orient, SD 57467
    View details
    Garretson Mixed-Use Investment Property
    $120,000
    1,414 SF

    Garretson Mixed-Use Investment Property

    Mixed-use property with commercial and residential units, generating cash flow.

    524 N Main Ave, Garretson, SD 57030
    View details
    Spearfish Commercial Building with Expansion Potential
    $1,299,000
    9,600 SF

    Spearfish Commercial Building with Expansion Potential

    Established commercial building near I-90 with income and expansion potential.

    3103 E Fairgrounds Loop, Spearfish, SD 57783
    View details
    Spearfish Mixed-Use Investment Opportunity
    $1,599,000
    3,950 SF

    Spearfish Mixed-Use Investment Opportunity

    Successful business and investment property on 1.62 acres near Exit 8.

    3225 Old Belle Road, Spearfish, SD 57783
    View details
    Prime Custer Mixed-Use Investment
    $2,300,000
    8,700 SF

    Prime Custer Mixed-Use Investment

    Renovated mixed-use property with retail and short-term rental income.

    632 Mt. Rushmore Road, Custer, SD 57730
    View details
    Versatile Commercial Property in Belle Fourche
    $149,900
    2,880 SF

    Versatile Commercial Property in Belle Fourche

    Commercial property with business and residential potential in Belle Fourche.

    930 Harding Street, Belle Fourche, SD 57717
    View details
    Land with Building in Vale
    $349,900
    0.41 Acres

    Land with Building in Vale

    Versatile property with home, shop, and extra living/business space.

    209 Pierre Street, Vale, SD 57788
    View details
    Main Street Commercial Building
    $295,000
    3,504 SF

    Main Street Commercial Building

    Commercial building with income-producing apartment on Main Street.

    1023 S MAIN Street, Aberdeen, SD 57401
    View details
    Versatile Mixed-Use Property in Tea
    $1,400,000
    5,320 SF

    Versatile Mixed-Use Property in Tea

    5,320 SF mixed-use property with showroom and warehouse space.

    820 Gateway Lane, Tea, SD 57064
    View details
    Renovated Commercial Property in Mobridge
    $525,000
    5,360 SF

    Renovated Commercial Property in Mobridge

    5,360 sq ft commercial property with multi-tenant potential.

    1710 E GRAND XING, Mobridge, SD 57601
    View details
    Multi-Purpose Facility Near Convention Center
    $2,600,000
    13,536 SF

    Multi-Purpose Facility Near Convention Center

    Investment opportunity: 14,000 SF mixed-use property near Denny Sanford Center.

    1605 W Burnside St, Sioux Falls, SD 57104
    View details
    Versatile Commercial Property For Sale
    $298,000
    1,800 SF

    Versatile Commercial Property For Sale

    Mixed-use commercial property suitable for retail, office, or industrial use.

    1325 E Cherry Street, Vermillion, SD 57069
    View details
    Versatile Mixed-Use Property in Madison
    $380,000
    5,612 SF

    Versatile Mixed-Use Property in Madison

    Mixed-use property near downtown Madison and Dakota State University.

    610 NE 3rd St, Madison, SD 57042
    View details
    Mixed-Use Property With Retail
    $875,000
    12,554 SF

    Mixed-Use Property With Retail

    Mixed-use property featuring apartments and retail spaces for sale.

    2412 E 10th St, Sioux Falls, SD
    View details
    25.86 Acres Development Opportunity
    $2,084,000
    25.86 Acres

    25.86 Acres Development Opportunity

    Two parcels totaling 25.86 acres with strong traffic.

    3817 3rd Ave SE, Aberdeen, SD 57401
    View details
    Spearfish Commercial Shop/Office Building
    $1,599,000
    9,860 SF

    Spearfish Commercial Shop/Office Building

    Commercial building in Spearfish, SD with five leased units.

    320 S 26th St, Spearfish, SD 57783
    View details
    Mixed-Use Property Near Arrowhead Pkwy
    $1,100,000
    8,750 SF

    Mixed-Use Property Near Arrowhead Pkwy

    Two buildings with office, shop, and storage spaces for sale.

    600 S Charlotte Ave, Sioux Falls, SD 57103
    View details
    Highway 212 Commercial Property
    $448,000
    3,816 SF

    Highway 212 Commercial Property

    Commercial property on Highway 212 with two buildings.

    211 9th Avenue Southeast, Watertown, SD 57201
    View details

    South Dakota Mixed-Use Properties Investment Opportunities Market Analysis

    Explore 72 mixed-use properties for sale in South Dakota, showcased through 31 active listings on our real estate platform. These investment opportunities span a total of 148,223 square feet of properties for sale, with an estimated market value of $17,602,700.

    Sale prices for multi use buildings in South Dakota start at $129,900, averaging $800,122, and reaching up to $2,600,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

    List
    Map

    Mixed-use properties by market

    Popular cities

    Popular Categories

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!