Health Care

South Dakota Healthcare Properties for Sale

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Sioux Falls, SD Rapid City, SD Aberdeen, SD Spearfish, SD Lead, SD Watertown, SD Tea, SD Huron, SD
9 properties
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Mixed-Use Building with Apartments
Updated: Oct 5
Mixed-Use Building with Apartments

210 W Main St, Canistota, SD 57012

$269,900
2,928 sqft 0.13 AC lot
2,928‑square‑foot mixed‑use property on 0.1343 acres
Two upper‑level apartments, each with 2 bedrooms and 1 bathroom
Separate exterior entrance for each apartment
Both apartments are currently leased
Ground floor includes a massage therapy business and additional commercial space
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Downtown Retail Space
Updated: Apr 28
Downtown Retail Space

407 S Main St, Platte, SD 57369

$79,000
1,180 sqft 0.08 AC lot
1,180 square feet of retail space
25' x 140' lot
2019 improvements included flooring, lighting, partial electrical work, and a new roof
More recent water heater installation
Built in 1910
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Renovated Medical Office Space
Renovated Medical Office Space

747 Ames Ave, Spearfish, SD 57783

$998,500
2,400 sqft

The facility accommodates a chiropractic practice and spa with multiple offices and two bathrooms.

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Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center
Assisted Living Facility For Sale
Assisted Living Facility For Sale

409 East Fairlane Drive, Rapid City, SD 57701

$1,500,000
44,150 sqft 1.91 AC lot

Assisted living facility with expansion potential in Rapid City, SD.

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Rapid City Assisted Living Facility
Rapid City Assisted Living Facility

1321 Columbus Street, Rapid City, SD 57701

$5,000,000
21,895 sqft 1.64 AC lot

48-bed assisted living facility in Rapid City, South Dakota.

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Medical Campus with Indoor Pool
Medical Campus with Indoor Pool

2501 & 2505 W. 26th Street, Sioux Falls, SD 57105

$9,900,000
6.78 AC lot

Institutional facility with classrooms, residential areas, offices, a kitchen, garage, elevator access, and dedicated surface parking.

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Spa & Wellness Property with Massage Room
Spa & Wellness Property with Massage Room

430 Quincy St, Rapid City, SD 57701

$249,000

Existing salon layout includes multiple service stations and a dedicated massage room.

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Multi-Use Hospitality Resort & Event Center
Multi-Use Hospitality Resort & Event Center

603 N River St, Hot Springs, SD 57747

$1,550,000

Resort property includes short-term rentals, an event center for up to 250 guests, and an on-site spa and wellness area.

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Versatile Commercial Building on Sioux Avenue
Versatile Commercial Building on Sioux Avenue

604 E Sioux Ave, Pierre, SD

Contact for pricing
2,085 sqft 0.39 AC lot

Adaptable commercial property with high visibility and drive-through canopy.

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Based on your search, we've compiled 72 Potential Opportunities for your consideration. Besides 9 Active listings in South Dakota, we suggest exploring several alternatives: similar 63 Off-Market properties to explore as potential leads

Off-Market Properties in South Dakota

Consider similar Off-Market properties in South Dakota. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

6301 41st St
MEDICAL BUILDING

6301 41st St, Sioux Falls, SD 57106-1217

Estimated value:
$2,000,000
3,108 sqft 0.35 AC lot
View details
803 23rd St
HOMES (RETIRED, NURSING)

803 23rd St, Sioux Falls, SD 57105-2107

Estimated value:
$400,000
4,405 sqft 1.91 AC lot
View details
3413 Phillips Ave
HOMES (RETIRED, NURSING)

3413 Phillips Ave, Sioux Falls, SD 57105-6449

Estimated value:
$225,000
8,153 sqft 0.77 AC lot
View details
2815 Westlake Dr
HOMES (RETIRED, NURSING)

2815 Westlake Dr, Sioux Falls, SD 57106-8529

Estimated value:
$52,565,000
55,998 sqft 5.42 AC lot
View details
920 4th St
HOMES (RETIRED, NURSING)

920 4th St, Garretson, SD 57030-2006

Estimated value:
$4,295,000
26,452 sqft 2.29 AC lot
View details
730 Park Ave
HOMES (RETIRED, NURSING)

730 Park Ave, Colton, SD 57018

Estimated value:
$1,000,000
11,640 sqft 2.88 AC lot
View details
101 37th St
DENTAL BUILDING

101 37th St, Sioux Falls, SD 57105-5701

Estimated value:
$440,000
11,259 sqft 1.60 AC lot
View details
409 Western Ave
HOMES (RETIRED, NURSING)

409 Western Ave, Sioux Falls, SD 57104-5607

Estimated value:
$1,460,000
17,167 sqft 1.40 AC lot
View details
2600 Western Ave
DENTAL BUILDING

2600 Western Ave, Sioux Falls, SD 57105-4429

Estimated value:
$490,000
2,948 sqft 0.23 AC lot
View details
749 Streeter Dr
HOMES (RETIRED, NURSING)

749 Streeter Dr, North Sioux City, SD 57049-4112

Estimated value: by Request
17,700 sqft 2.32 AC lot
View details
2301 Lorraine Pl
DENTAL BUILDING

2301 Lorraine Pl, Sioux Falls, SD 57106-3642

Estimated value:
$320,000
1.66 AC lot
View details
4501 Pampas Pl
HOMES (RETIRED, NURSING)

4501 Pampas Pl, Sioux Falls, SD 57110-4601

Estimated value:
$1,020,000
41,280 sqft 2.75 AC lot
View details
809 Belfast St
MEDICAL BUILDING

809 Belfast St, Yankton, SD 57078-3324

Estimated value:
$335,000
2,482 sqft 0.30 AC lot
View details
3803 Louise Ave
HOMES (RETIRED, NURSING)

3803 Louise Ave, Sioux Falls, SD 57107-0115

Estimated value:
$205,000
7,990 sqft 1.97 AC lot
View details
305 5th St
HOMES (RETIRED, NURSING)

305 5th St, Hartford, SD 57033-2275

Estimated value:
$1,775,000
11,226 sqft 0.87 AC lot
View details

South Dakota Healthcare Properties Market Trends and Statistics

Explore 72 healthcare properties for sale in South Dakota, showcased through 9 active listings on our real estate platform. These investment opportunities span a total of 71,710 square feet of properties for sale, with an estimated market value of $19,276,500.

Sale prices for medical real estate in South Dakota start at $79,000, averaging $2,753,785, and reaching up to $9,900,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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