Health Care

South Dakota Healthcare Properties for Sale

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Sioux Falls, SD Rapid City, SD Aberdeen, SD Huron, SD Lead, SD Watertown, SD Spearfish, SD Tea, SD
9 properties
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Multi-Tenant Storefront Property
Updated: Jul 28
Multi-Tenant Storefront Property

423 Moccasin Drive, Aberdeen, SD 57401

$429,000
3,024 sqft
3,024‑square‑foot multi‑tenant commercial building
Built in 1989
Paved parking is available on the property
East US Highway 12 is nearby
Located at 423 Moccasin Drive, Aberdeen, SD 57401
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423 Moccasin Drive, Aberdeen, SD 57401

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Medical Center with Veterinary Facilities
Updated: Aug 15, 2025
Medical Center with Veterinary Facilities

1603 Broadway Ave, Yankton, SD 57078

$999,900
3,480 sqft 0.31 AC lot
3480 square feet on 0.31 acres
Veterinary facility serving small and large animals
Grooming and boarding equipment included
Up to 13 off‑street parking spaces
6+ on‑street (employee) parking spaces
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Assisted Living Facility For Sale
Assisted Living Facility For Sale

409 East Fairlane Drive, Rapid City, SD 57701

$1,500,000
44,150 sqft 1.91 AC lot

Assisted living facility with expansion potential in Rapid City, SD.

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Rapid City Assisted Living Facility
Rapid City Assisted Living Facility

1321 Columbus Street, Rapid City, SD 57701

$5,000,000
21,895 sqft 1.64 AC lot

48-bed assisted living facility in Rapid City, South Dakota.

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Multi-Use Hospitality Resort & Event Center
Multi-Use Hospitality Resort & Event Center

603 N River Street, Hot Springs, SD 57747

Contact for pricing
32,576 sqft

Resort property includes short-term rentals, an event center for up to 250 guests, and an on-site spa and wellness area.

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Deadwood Mountain Grand Resort
Deadwood Mountain Grand Resort

1906 Deadwood Mountain, Deadwood, SD 57732

Contact for pricing

98-room resort with event space, casino, full-service spa, indoor pool, and a 220-space parking garage.

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Versatile Commercial Building on Sioux Avenue
Versatile Commercial Building on Sioux Avenue

604 E Sioux Ave, Pierre, SD

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2,085 sqft 0.39 AC lot

Adaptable commercial property with high visibility and drive-through canopy.

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Platte Assisted Living Facility
Platte Assisted Living Facility

211 Iowa Ave, Platte, SD 57369

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8,467 sqft

14-room assisted living facility in Platte, South Dakota.

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Assisted Living Care Facility
Assisted Living Care Facility

210 E 3rd St, Ramona, SD 57054

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Well-maintained facility with front or rear yard parking, plus a single-stall garage and space for expansion.

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Based on your search, we've compiled 72 Potential Opportunities for your consideration. Besides 9 Active listings in South Dakota, we suggest exploring several alternatives: similar 63 Off-Market properties to explore as potential leads

Off-Market Properties in South Dakota

Consider similar Off-Market properties in South Dakota. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

6301 41st St
MEDICAL BUILDING

6301 41st St, Sioux Falls, SD 57106-1217

$2,000,000
Estimated value
3,108 sqft 0.35 AC lot
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803 23rd St
HOMES (RETIRED, NURSING)

803 23rd St, Sioux Falls, SD 57105-2107

$400,000
Estimated value
4,405 sqft 1.91 AC lot
View details
3413 Phillips Ave
HOMES (RETIRED, NURSING)

3413 Phillips Ave, Sioux Falls, SD 57105-6449

$225,000
Estimated value
8,153 sqft 0.77 AC lot
View details
2815 Westlake Dr
HOMES (RETIRED, NURSING)

2815 Westlake Dr, Sioux Falls, SD 57106-8529

$52,565,000
Estimated value
55,998 sqft 5.42 AC lot
View details
920 4th St
HOMES (RETIRED, NURSING)

920 4th St, Garretson, SD 57030-2006

$4,295,000
Estimated value
26,452 sqft 2.29 AC lot
View details
730 Park Ave
HOMES (RETIRED, NURSING)

730 Park Ave, Colton, SD 57018

$1,000,000
Estimated value
11,640 sqft 2.88 AC lot
View details
101 37th St
DENTAL BUILDING

101 37th St, Sioux Falls, SD 57105-5701

$440,000
Estimated value
11,259 sqft 1.60 AC lot
View details
409 Western Ave
HOMES (RETIRED, NURSING)

409 Western Ave, Sioux Falls, SD 57104-5607

$1,460,000
Estimated value
17,167 sqft 1.40 AC lot
View details
2600 Western Ave
DENTAL BUILDING

2600 Western Ave, Sioux Falls, SD 57105-4429

$490,000
Estimated value
2,948 sqft 0.23 AC lot
View details
749 Streeter Dr
HOMES (RETIRED, NURSING)

749 Streeter Dr, North Sioux City, SD 57049-4112

Value Estimation by Request
17,700 sqft 2.32 AC lot
View details
2301 Lorraine Pl
DENTAL BUILDING

2301 Lorraine Pl, Sioux Falls, SD 57106-3642

$320,000
Estimated value
1.66 AC lot
View details
4501 Pampas Pl
HOMES (RETIRED, NURSING)

4501 Pampas Pl, Sioux Falls, SD 57110-4601

$1,020,000
Estimated value
41,280 sqft 2.75 AC lot
View details
809 Belfast St
MEDICAL BUILDING

809 Belfast St, Yankton, SD 57078-3324

$335,000
Estimated value
2,482 sqft 0.30 AC lot
View details
3803 Louise Ave
HOMES (RETIRED, NURSING)

3803 Louise Ave, Sioux Falls, SD 57107-0115

$205,000
Estimated value
7,990 sqft 1.97 AC lot
View details
305 5th St
HOMES (RETIRED, NURSING)

305 5th St, Hartford, SD 57033-2275

$1,775,000
Estimated value
11,226 sqft 0.87 AC lot
View details

South Dakota Healthcare Properties Market Trends and Statistics

Explore 72 healthcare properties for sale in South Dakota, showcased through 9 active listings on our real estate platform. These investment opportunities span a total of 115,677 square feet of properties for sale, with an estimated market value of $7,928,900.

Sale prices for medical real estate in South Dakota start at $429,000, averaging $1,982,225, and reaching up to $5,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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