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Cape Girardeau, MO Medical Offices for Sale

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Renovated Downtown Commercial Property
$550,000
4,548 SF

Renovated Downtown Commercial Property

224 N Frederick St, Cape Girardeau, MO 63701

Versatile, renovated 11-bedroom property in downtown Cape Girardeau, Missouri.

  • Prime downtown location steps from dining, shopping, and campus.
  • Proven income‑producing property as a high‑demand sorority house.
  • Fully renovated in 2020 with 11 bedrooms and over 5,100 square feet.
  • Versatile property suitable for group housing, student rentals, or professional office space.
  • Generous lot with twenty‑five parking spaces.
Updated: Jan 9
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Cape Girardeau Commercial Property
Pending
$825,000
7,000 SF

Cape Girardeau Commercial Property

340 S Broadview St, Cape Girardeau, MO 63703

Well-maintained commercial property with over 7,000 square feet.

  • Over 7,000 square feet of usable space.
  • Highly visible and convenient location.
  • Suitable for a wide range of professional or medical uses.
  • Ample on‑site parking for staff and visitors.
  • ADA compliance throughout.
Updated: Dec 1, 2025
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Commercial Building with Abundant Parking
$2,500,000

Commercial Building with Abundant Parking

Versatile commercial building on 1.9 acres with ample parking.

1429 N Mount Auburn Rd, Cape Girardeau, MO 63701
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Based on your search, we've compiled 8 Potential Opportunities for your consideration. Besides 3 Active listings in Cape Girardeau, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 1 Off-Market properties to explore as potential leads

Explore Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Carbondale Flex Space - $249,900
$249,900

Carbondale Flex Space - $249,900

Updated Commercial Building, Excellent Location

1001 Beadle Dr, Carbondale, IL 62901
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Remodeled Office Space For Sale
$249,900
0.14 Acres

Remodeled Office Space For Sale

Remodeled office space in Carbondale, perfect for medical or general use.

1001 N Beadle Dr, Carbondale, IL 62901
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Single Tenant Investment Property
$2,150,000

Single Tenant Investment Property

Leased to U.S. Department of Veterans Affairs Outpatient Clinic.

2620 Perkins Creek Dr, Paducah, KY 42001
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Paducah Medical Center For Sale
$1,449,586
6,715 SF

Paducah Medical Center For Sale

100% leased Class B medical center in Paducah, Kentucky.

3121 Parisa Dr, Paducah, KY 42003
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Explore Off-Market Properties in Cape Girardeau, MO

Consider similar Off-Market properties in Cape Girardeau, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

3049 William St

3049 William St

Medical offices • 79,122 SF
Value Estimation by Request
3049 William St, Cape Girardeau, MO 63703
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Cape Girardeau, MO Medical Offices Investment Opportunities Market Analysis

Explore 4 medical offices for sale in Cape Girardeau, MO, showcased through 3 active listings on our real estate platform. These investment opportunities span a total of 57,525 square feet of properties for sale, with an estimated market value of $1,375,000.

Prices for medical spaces in Cape Girardeau, MO start at $550,000, averaging $687,500, and reaching up to $825,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you have the most current data.

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