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Medical Office Space on Large Lot
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5107 Medical Dr, San Antonio, TX 78229

Medical-office site in San Antonio’s Medical Center area with substantial land area and nearly 28,000 SF.

Space Size27,494 SF
Lot Size2.69 Acres
Days on Market526

Property Features for 5107 Medical Dr

General Information

Standard status Active
Size 27,494 SF
Net Rentable 27,494 SF
Lot size 2.69 Acres
Property subtype OFFICE

Space & Availability

Available Space 27,494 SF
Contiguous Space 27,494 SF
Space Use Medical Office

Site & Location

Neighborhood Leon Valley
Highway Access Yes
Public Transit Yes

Building Details

Building Size 27,494 SF

Spaces For Lease

at 5107 Medical Dr
5107 Medical Drive in San Antonio, TX 78229 AVAILABLE, Now
Size 27,494 SF
Type OFFICE
Rate Contact for pricing
Situated at 5107 Medical Dr in San Antonio, TX 78229, this property is ideally located within San Antonio's bustling Medical Center area. This site offers unparalleled proximity to major healthcare facilities, making it a valuable spot for medical offices, clinics, or other healthcare-focused developments. With easy access to major highways and public transportation, the property is convenient for both professionals and patients. This location presents an excellent investment opportunity in a high-demand are, ideal for a medical or commercial project that will benefit from the area's high foot traffic and vibrant community. Property Characteristics Address: 5107 Medical Drive, San Antonio, TX 78229 Asset Type: Medical/Office Asset Square Footage: ±27,494 SF Land Area: ±2.6900 AC APN: 13663-00-0087 Legal Description: NCB 13663 BLK LOT SE IRR 448.54' OF 8 or ARB 8C
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Listing Agency: Colliers - Houston
Listed By: Jeff Peltier · License #525004
Source: Moodyscre
Added: May 27, 2025 Changed: Nov 1 Last Checked: Nov 1 at 2:15AM

Displayed information is deemed reliable but is not guaranteed and should be independently verified. All listing content including descriptions, pricing, images are the copyrighted material of Colliers - Houston

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Investment Insights

Based on property information with market context.

This medical-office site at 5107 Medical Dr offers approximately 27,494 SF of space and a land area of about 2.69 AC. The legal description is NCB 13663 BLK LOT SE IRR 448.54' OF 8 or ARB 8C, with APN 13663-00-0087.

Located within San Antonio’s Medical Center area, the property is positioned for healthcare-related uses, including medical offices and clinics. The site is described as having easy access to major highways and public transportation, supporting convenience for both professionals and patients.

The combination of a medical-office focus, ample land area, and Medical Center proximity makes this a practical fit for healthcare-focused development or office uses that benefit from consistent demand in the surrounding area.

Key Highlights

  • 5107 Medical Dr, San Antonio, TX 78229 Medical Center area
  • Approximately 27,494 SF medical‑office space
  • Approximately 2.69 AC land area

Property Analytics

Who owns this building? See the owner, sales and loan history
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Current Use

Stacie K. Haller, ... Physician Mahendra Ghanta Health Care Facility Jerome Fischer Physician Diabetes & Glandular Disease ... Medical Clinic Scott Karen Physician

Suggested Use

Top Pick Hair Salon Law Firm Food Market Grocery & Convenience Store Nail Salon Kitchen & Bath Showroom

Score = modeled unmet demand for each use within ~1 mi (higher = bigger opportunity). Zoning and permitted uses should be independently verified with local authorities.

Lease Details

Yes
Highway access
NNN (Triple Net)
Lease Type

Location Intelligence

Trade Area within ½ mile

4,845
Businesses Nearby
Under-served
Demand for This Use

Demographics for 78229, TX

33,135
Population
19,149
Households
1.7
Avg Household Size
31
Median Age
31%
College-Educated
86%
High-School Grad
5.8 sq mi
ZIP Area
5,713
Density / Sq Mi
$46,718
Median Household Income
$32,888
Median Earnings
$1,234
Median Rent
$206,400
Median Home Value
Check the figures for this property Cap Rate, Value Estimation, Potential NOI and more
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Market

Lease Benchmarks for San Antonio, TX

$30.35 /SF/Yr
Avg Asking Price
$7.52–$111 /SF/Yr
Price Range
4,903 SF
Avg Space Size

Vacancy Rate% for Office in San Antonio, TX

13.5% 2019
13.4% 2021
15.7% 2022
17.3% 2023
16.5% 2024
16% 2025

Similar Off Market Nearby

  • Audie Murphy Memorial Vet Hospital: Herrman Terry MD — 7400 Merton Minter, San Antonio, TX 78229

Frequently Asked Questions

What type of property is this?
Medical Office Space - Medical-office site in San Antonio’s Medical Center area with substantial land area and nearly 28,000 SF.
Where is this medical office space located?
The property is located at 5107 Medical Dr San Antonio, TX.
What are key features of this property?
This property features: 5107 Medical Dr, San Antonio, TX 78229 Medical Center area; Approximately 27,494 SF medical‑office space; Approximately 2.69 AC land area
(713) 830-2182 Call to check price and availability
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