San Antonio, TX Office buildings for Rent & Lease

Updated: Apr 15

North Central San Antonio Office

13003 Jones Maltsberger Road, San Antonio, TX 78247

$18 SF/Yr

3,520 sqft

Prime location directly across from McAllister Park in desirable North Central San Antonio.
Updated office build‑out features spacious open areas, conference rooms, and a full kitchen.
Excellent accessibility: minutes from Hwy 281, San Antonio International Airport, and Wurzbach Parkway.
Strong traffic counts and excellent area demographics.
Outstanding visibility and available signage.

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Updated: Mar 25

Office Complex with Landscaped Grounds

4242 Medical Drive, San Antonio, TX 78229

$19 SF/Yr

1,780 sqft

Master‑planned office complex.
Located on the corner of Medical Drive and Fredericksburg Road.
Ingress and egress to both major thoroughfares.
Beautifully landscaped grounds.
Large oak trees.

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Renovated Multi-Tenant Office Space

11103 West Avenue, San Antonio, TX 78213

$14.50 SF/Yr

11,098 sqft

Modern office space in San Antonio's North Central submarket.

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San Antonio Office Business Park

11815 - 11865 IH 10 West, San Antonio, TX 78230

$18.50 SF/Yr

75,049 sqft

One-story office spaces with high visibility and convenient location.

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Class A Office Space Available

4801 Northwest Loop 410, San Antonio, TX 78229

$26 SF/Yr

13,915 sqft

High-rise office building in San Antonio's Northwest, ready for move-in.

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Two-Story Office Building

975 W Bitters Rd., San Antonio, TX 78216

Contact for pricing

4,320 sqft

A lighted marquee sign provides on-site business identification for the renovated office property.

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Office Building Near Highway 281

12950 Country Parkway, San Antonio, TX 78216

$19 SF/Yr

6,656 sqft

One-story office building with easy highway access and full-service amenities.

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Medical Office Space Under Construction

8435 Wurzbach Road, San Antonio, TX 78229

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7,868 sqft

Five-story Phase II building planned within a mixed-use medical development.

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Office Suites with Covered Parking

6100 Bandera Road, San Antonio, TX 78238

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5,848 sqft

Well-managed office space offering a building conference area, on-site cafe, and covered parking for everyday convenience.

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Office Building Near TX-151

10010 Rogers Xing, San Antonio, TX 78251

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8,569 sqft

Office space with easy TX-151 access near multiple Westover Hills medical facilities.

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Office Building with Covered Parking

6100 Bandera Rd, San Antonio, TX 78238

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5,848 sqft

Office building offering on-site property management, a building conference area, an on-site cafe, and covered parking.

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Updated Office in Government Hill

1422 East Grayson Street, San Antonio, TX 78208

$26 SF/Yr

30,052 sqft

Class A office space in walkable Government Hill neighborhood.

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Office Space at The Rim

18302 Talavera Ridge, San Antonio, TX 78257

$25 SF/Yr

18,747 sqft

Office space in a vibrant mixed-use development.

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Freestanding Office Building

San Antonio, TX 78217

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1,554 sqft

Configured with individual rooms, reception space, and on-site parking for professional or medical occupancy.

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Centrally Located Office Building

519 East Quincy Street, San Antonio, TX 78215

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4,550 sqft

Office building features a large entry, conference room, and 15+ private offices with ample on-site parking.

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Class A Medical Office Space

3903 Wiseman Blvd, San Antonio, TX 78251

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779 sqft

Healthcare practices share access to imaging, laboratory services, covered patient drop-off, and free surface parking.

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New Office Building with Ballroom

660 North Main Avenue, San Antonio, TX 78205

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8,721 sqft

Move-in-ready office space with conference, refreshment, dining, and event facilities.

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Single-Story Office Building

6007-6029 Fountainwood Drive, San Antonio, TX 78233

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10,225 sqft 1.11 AC lot

Zoned C3-NA, the office property has connections to Loop 1604 and Interstate 35.

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Class A Mixed-Use Office/Retail

200 Concord Plz Dr, San Antonio, TX 78216

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1,149 sqft 9.00 AC lot

Concord Plaza features an 11-story office tower, a 3-story office building, and ground-floor retail space.

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Office Building in Innovation Campus

1305 E Houston St, San Antonio, TX 78205

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1,175 sqft

Merchants Ice Building is part of a redeveloped historic campus and is home to VelocityTX Innovation Center.

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Office Building Lease Space

112 East Pecan Street, San Antonio, TX 78205

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33,987 sqft

Office leasing option at 112 East Pecan Street in San Antonio for businesses seeking dedicated workspace.

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Three-Story Office Building

13333 Blanco Road, San Antonio, TX 78216

$22 SF/Yr

Three-story office building with covered and surface parking, plus signage opportunities on Blanco Road.

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Office Building with On-Site Surgery Center

423 TREELINE PARK, San Antonio, TX 78209

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6,174 sqft

Three-story office and medical building with an on-site surgery center and reserved covered parking.

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Garden Office Building

4800 Fredericksburg Rd, San Antonio, TX 78229

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2,643 sqft

Garden office building with covered parking and monument signage near Loop 410 and IH-10.

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San Antonio, TX Office buildings Lease Rates & Market Statistics

Browse 116 Office buildings for lease in San Antonio, TX on Realmo, a commercial real estate marketplace serving the San Antonio area. The current inventory totals 1,701,630 square feet of properties — an average of ~14,650 SF per listing.

Office buildings lease rates in San Antonio range from $14.50 SF/Yr at the entry level to $26 SF/Yr at the top of the market, averaging $20.68 SF/Yr. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings. At $20.68 SF/Yr, the local average runs 11% below Texas's state average of $23.23 SF/Yr.

Office buildings make up 27% of the 434 Office Spaces currently for lease in San Antonio, with asking rates in line with the citywide Office Spaces average. Tenants comparing options may also consider Office Units (228 listings) and Medical Office Space (103 listings) elsewhere in the San Antonio market.