San Antonio, TX Mixed-use Properties for Lease

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Updated: Mar 25

Mixed-Use Development Retail Space

18402 U.S. Highway 281 North, San Antonio, TX 78259

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17,936 sqft

Dominant mixed‑use center in San Antonio.
Incredible visibility with frontage on Hwy 281 and Loop 1604.
Strong regional tenancy including Best Buy, Specs, Lifetime Fitness, Buffalo Wild Wings, and Starbucks.
Located at the intersection of US Hwy 281 North and Loop 1604.
Surrounded by strong demographics.

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Updated: Nov 22, 2025

Office Space at The Rim

18302 Talavera Ridge, San Antonio, TX 78257

$25 SF/Yr

38,049 sqft

Located in The Rim, a vast mixed‑use development for entertainment, dining, and shopping.
High parking ratio of 8.0/1000 with a 538‑space parking garage.
Premier location for employee recruiting.
Adjacent to luxury multi‑family living.
Large, efficient floor plates.

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Class A Mixed-Use Retail/Office Space

1803 N Loop 1604 W, San Antonio, TX 78259

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3,200 sqft

3,200 SF available within a Class A mixed-use development anchored by Life Time Fitness at a high-traffic Loop 1604 intersection.

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San Antonio Mixed-Use Property

738 West Hildebrand Avenue, San Antonio, TX 78212

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Mixed-use property available for rent in San Antonio, Texas.

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Retail, Office

4939 De Zavala Rd, San Antonio, TX 78249

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7,406 sqft

Mixed-use properties · 7,406 SF

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New Mixed-Use Development For Rent

25765 I-10, San Antonio, TX

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9,237 sqft

Two-story mixed-use development with frontage along IH-10.

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Mixed-Use Property Available For Lease

Texas 151 Access Rd, San Antonio, TX 78245

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15,775 sqft

Mixed-use property featuring retail, office, and land for lease.

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Mixed-Use Project Near Pearl Brewery

1900 Broadway, San Antonio, TX 78215

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Mixed-use project with retail spaces, prominent visibility, and high-end finishes.

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Mixed-Use Development in Stone Oak

115, 123 & 139 N Loop 1604 E, San Antonio, TX 78248

$30 SF/Yr

Mixed-use development with retail, office, and restaurant spaces for lease.

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Mixed-Use Development Retail Opportunity

19338 Babcock Rd, San Antonio, TX 78256

$26 SF/Yr

2,300 sqft

Proposed mixed-use development with retail and restaurant opportunities.

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San Pedro Mixed-Use Property

600 San Pedro Ave, San Antonio, TX 78212

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10,694 sqft

Mixed-use property with retail and warehouse space for lease.

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Mixed-Use Development Opportunity

I-10 Frontage Rd and Balcones Creek, San Antonio, TX 78006

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Mixed-use development with retail, residential, and office spaces.

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Based on your search, we've compiled 31 Potential Opportunities for your consideration. Besides 12 Active listings in San Antonio, TX, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 11 Properties for Sales.

Mixed-use properties for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Mixed-Use Complex with Retail & Office

Austin, TX 78738

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713,000 sqft

Multi-use complex featuring retail, office, apartments, and residential condominiums.

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Grocery-Anchored Mixed-Use Development

29690 Frontage Rd, Boerne, TX

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5,450 sqft

118-acre mixed-use development near San Antonio and Boerne, Texas.

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Grocery-Anchored Mixed-Use Development

29620 I-10, Boerne, TX

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14,036 sqft

118-acre mixed-use development near San Antonio and Boerne, Texas.

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Office and Warehouse Space Available

14101 US-290, Austin, TX 78737

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110,000 sqft

Condo-style office and flex/warehouse space for lease.

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Similar Spaces for Sale in San Antonio, TX

Consider Similar Space for Sale. We found 11 Spaces matching your search parameters.

Highway Frontage Commercial Space

12567 S U.S. Hwy 181, San Antonio, TX 78223

$1,500,000

1,639 sqft

Versatile commercial space with high visibility and accessibility.

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Prime Land Near Braun Dance Hall

9721 Braun Rd, San Antonio, TX 78254

$1,825,000

5,400 sqft 4.87 AC lot

4.87 acres of commercial land near Braun Dance Hall.

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Alamo Heights Freestanding Office Space

5721 Broadway St, San Antonio, TX

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2,536 sqft 0.25 AC lot

Freestanding office in prime Alamo Heights location for lease.

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Mixed-Use Property in San Antonio

321 6th St, San Antonio, TX 78215

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11,229 sqft

11,229 SqFt mixed-use property available for sale.

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San Antonio Mixed-Use Property

4903 GOLDEN QUAIL, San Antonio, TX 78240

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2,940 sqft

2,940 SF mixed-use property suitable for industrial, office, retail.

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Midtown San Antonio Investment Portfolio

319 E Euclid Ave, San Antonio, TX 78212

$1,200,000

1,990 sqft 0.37 AC lot

Income-producing mixed-use portfolio near downtown San Antonio.

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Government Hill Development Opportunity

1622 N Pine St, San Antonio, TX 78208

$350,000

1,031 sqft 0.37 AC lot

Prime 0.37-acre development site in Government Hill, San Antonio.

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Mixed-Use Property For Sale

5671 Randolph Blvd, San Antonio, TX 78233

$750,000

Mixed-use property available for sale.

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Impressive Building on Prime Land

8531 W Loop 1604 N, San Antonio, TX 78254

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18,200 sqft 7.40 AC lot

18,200 SF building on 7.40 AC in San Antonio.

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Denver Heights Redevelopment Opportunity

910 Clark Ave, San Antonio, TX 78210

$40,000

Prime investment opportunity in growing Denver Heights area.

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Multi-Tenant Investment Property For Sale

5421 Grissom Rd, San Antonio, TX 78238

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6,900 sqft 0.50 AC lot

Multi-tenant property in high-traffic area, fully leased to two tenants.

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Cleared Commercial Lot For Lease

943 King Arthur, New Braunfels, TX 78130

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1.33-acre commercial lot in growing New Braunfels market.

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9.6 Acres Commercial Land Available

23629 Southeast H K Dodgen, Temple, TX 76502

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9.6 acres of commercial land suitable for mixed-use development.

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Commercial Land For Rent

2719 Meyersville, Dallas, TX 75212

$1,000/Mo

5,000 sqft

Fenced vacant lot near corner available for lease.

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Fenced Vacant Lot For Rent

2723 Meyersville, Dallas, TX 75212

$1,000/Mo

5,000 sqft

Vacant lot near Trinity Grove, available for lease.

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San Antonio, TX Mixed-use properties Market Trends and Statistics

Explore Mixed-use properties leasing options in San Antonio, TX with 12 listings featured on our commercial real estate exchange. The current inventory includes 41,616 square feet of properties with an estimated lease value of $60 SF/Yr.

Estimated lease rates for Mixed-use properties in San Antonio, TX begin at $9 SF/Yr, with an average of $20 SF/Yr and extend to $26 SF/Yr.

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