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Little Elm, TX Medical Office Space for Lease

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New Mixed-Use Development Available
$34 SF/Yr
1,390 SF

New Mixed-Use Development Available

2135 Oak Grove Pkwy, Little Elm, TX

Upscale professional, medical, retail, and restaurant spaces available Fall 2025.

  • Location on Oak Grove Pkwy near the entrance into Little Elm/Frisco off the fast growing 380 corridor
  • Upscale mixed use development
  • Professional / Medical Office Suites available
  • Fully Finished Out Suites
  • Three Professional / Medical Office Buildings
Updated: May 21, 2025
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New Construction Opportunity in Little Elm
Contact for pricing
6,000 SF

New Construction Opportunity in Little Elm

2045 FM 423, Little Elm, TX 75068

New construction retail/office space in a high-growth Little Elm location.

  • Premier new construction delivering Q1 2025.
  • 6,000 SF ground‑floor suite ideal for medical or professional office.
  • Located off high‑visibility FM 423 in Little Elm.
  • Adjacent to established anchors: Cook Children’s Pediatrics, Frisco Elm Dental, and Kiddie Academy.
  • Generous tenant improvement options.
Updated: Apr 13, 2024
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Based on your search, we've compiled 13 Potential Opportunities for your consideration. Besides 2 Active listings in Little Elm, TX, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 3 Properties for Sales.

Explore Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Frisco Office/Medical Building For Lease
$8,167/Mo

Frisco Office/Medical Building For Lease

Move-in ready office/medical building in Frisco, TX available for lease.

425 Old Newman Road, Frisco, TX 75036
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Retail and Office/Medical Spaces
Contact for pricing
4,000 SF

Retail and Office/Medical Spaces

Retail and office/medical spaces available for lease.

5017 Main St, The Colony, TX
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Retail and Office/Medical Space
Contact for pricing
5,900 SF

Retail and Office/Medical Space

Retail and office/medical spaces available for lease.

5101 Main St, The Colony, TX
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Frisco Office/Medical Space For Lease
$3,300/Mo
1,150 SF

Frisco Office/Medical Space For Lease

Newly built office space in a high-traffic Frisco location.

400 Stonebrook Pkwy Spc 1103, Frisco, TX 75036
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Explore Similar Spaces for Sale in Little Elm, TX

Consider Similar Space for Sale. We found 3 Spaces matching your search parameters.

Modern Office Suite For Sale
$430,000
0.03 Acres

Modern Office Suite For Sale

New office suite near FM 720 and FM 423.

2601 Little Elm Parkway, Little Elm, TX 75068
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Prime Office/Retail Location
$419,000
9.70 Acres

Prime Office/Retail Location

Excellent location suitable for various businesses, medical use, or retail.

2601 Little Elm Parkway, Little Elm, TX 75068
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Restaurant/Retail and Medical Space
Contact for pricing
11,602 SF

Restaurant/Retail and Medical Space

Restaurant/Retail and Medical space available for sale.

1180 E Eldorado Pkwy, Little Elm, TX
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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

El Paso Commercial Land Lease
$3,600/Mo

El Paso Commercial Land Lease

Commercial land for lease in a strategic El Paso location.

5538 E Paisano Drive, El Paso, TX 79905
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Highway 72 Corner Lot
$6,500/Mo
1,875 SF

Highway 72 Corner Lot

1.6 acre commercial lot for rent on Highway 72.

30472 Highway 72, Madison, AL 35756
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Grand Junction Commercial Land Lease
$9,656/Mo

Grand Junction Commercial Land Lease

0.74 acre commercial land for lease in Grand Junction.

Highway 6&50, Grand Junction, CO 81505
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Grand Junction Commercial Land Opportunity
$17,728/Mo

Grand Junction Commercial Land Opportunity

1.36 acre commercial land for lease in Grand Junction.

Sanford Drive, Grand Junction, CO 81505
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Little Elm, TX Medical Office Space Leasing Opportunities Market Analysis

Explore Medical Office Space leasing options in Little Elm, TX with 2 listings featured on our commercial real estate exchange. The current inventory includes 1,390 square feet of properties with an estimated lease value of $34 SF/Yr.

Estimated lease rates for Medical Office Space in Little Elm, TX begin at $34 SF/Yr, with an average of $34 SF/Yr and extend to $34 SF/Yr.
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