Philadelphia, PA Medical Office Space for Lease

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57 properties

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Updated: Apr 29

First-Floor Medical Office Suite

10101 ACADEMY Road, Philadelphia, PA 19114

$8,250/Mo

4,000 sqft

Prime first‑floor location in a well‑established neighborhood commercial center.
4000 square foot suite adaptable for multiple configurations.
Ideally suited for a wide variety of medical service uses.
Efficient layout with reception, exam rooms, private offices, and restrooms.
Central heating and central air conditioning.

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Updated: Aug 15

Bi-Level Office Suite

5222 CHESTER Avenue, Philadelphia, PA 19143

$4,300/Mo

0.10 AC lot

Approximately 2,580 SF of bi‑level commercial space
Four private offices, conference area, open workspaces, and storage closets
Approximately 10.5‑foot ceilings with abundant natural light
Private street‑level entrance with expansive glass frontage along Chester Avenue
Three completed bathrooms, including two ADA‑accessible bathrooms

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Historic Medical Office Space

5912 RIDGE Avenue, Philadelphia, PA 19128

$6,042/Mo

0.22 AC lot

Ground-floor professional space with private offices, reception, kitchenette, and substantial basement storage.

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Historic Ground-Floor Medical Office

5912 RIDGE AVENUE, Philadelphia, PA 19128

$6,042/Mo

2,900 sqft

Ground-floor workspace includes private offices, reception, a kitchenette, and one bathroom.

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Renovated Office Units

1802-4 S BROAD Street, Philadelphia, PA 19145

$4,995/Mo

0.07 AC lot

Professional workspace with private rooms, meeting space, staff kitchen, and accessible entry.

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Medical Office Space with Exam Rooms

4821 FRANKFORD Avenue, Philadelphia, PA 19124

$5,067/Mo

0.31 AC lot

Configured with reception, examination rooms, offices, storage, and two bathrooms for medical office use.

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Renovated Office Space with Reception

6713-15 OGONTZ Avenue, Philadelphia, PA 19126

$7,000/Mo

0.09 AC lot

Flexible professional workspace with private offices, meeting rooms, support areas, and public transportation access.

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Built-Out Office Space

3645 Lancaster Ave, Philadelphia, PA 19104

$25 SF/Yr

2,011 sqft

Office unit with basement space and flexibility for retail, fitness, medical, or neighborhood market uses.

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Ground-Floor Retail Space

626 S 3RD Street, Philadelphia, PA 19147

$3,350/Mo

0.03 AC lot

Masonry commercial space with a private courtyard, lower-level use, and flexible entry options.

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Office Units with Dental Approval

11880 BUSTLETON Avenue, Philadelphia, PA 19116

$900/Mo

Multiple professional suites offer central heating, with utilities and building expenses included in the lease.

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Renovated Medical Office Suite

6713 Ogontz Ave, Philadelphia, PA 19141

$7,000/Mo

3,800 sqft

Move-in-ready medical office space with reception, private offices, conference rooms, and a dedicated treatment or therapy room.

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Medical Office Space with Exam Rooms

1313 WOLF Street, Philadelphia, PA 19148

$2,400/Mo

0.02 AC lot

First-floor suite with reception, three exam rooms, and a finished lower level for storage and support functions.

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First-Floor Medical Office Space

7516 CITY Avenue, Philadelphia, PA 19151

$14,400/Mo

0.51 AC lot

Ground-level suite in a medical office building with central air, parking, and nearby retail amenities.

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Ground Floor Retail Space

305 N 15th St, Philadelphia, PA 19102

$4,500/Mo

2,480 sqft

Ground floor retail space includes a finished interior and an additional usable basement level.

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Medical Office Space with Private Yard

2248 E ALLEGHENY Avenue, Philadelphia, PA 19134

$1,500/Mo

0.03 AC lot

Existing lobby, central air, and adaptable plumbing support professional and healthcare-related occupancy.

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Medical Office with Basement Storage

2428 S BROAD Street, Philadelphia, PA 19145

$2,200/Mo

0.03 AC lot

Existing clinical layout includes central air and additional basement storage.

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First-Floor Commercial Studio with Showroom Windows

1-33 S 3rd St, Philadelphia, PA 19106

$4,400/Mo

1,242 sqft

First-floor commercial studio with large showroom-type windows and strong natural light, positioned near Old City attractions.

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Office Units with Lower Level

1701 POPLAR Street, Philadelphia, PA 19130

$1,200/Mo

0.02 AC lot

Masonry office space offers central HVAC, a first-floor powder room, and additional lower-level area.

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Retail Suite with Lease Availability

493 Domino Ln, Philadelphia, PA 19128

$2,999/Mo

1,700 sqft

Retail suite currently leased to a State Farm Insurance Agency, with lease-up available June 2026 or sooner.

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First-Floor Medical Office Condo

207 N Broad Street, Philadelphia, PA 19107

$22.50 SF/Yr

6,300 sqft

Turn-key medical office condo with convenient parking access and flexible use under CMX-4 zoning.

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Three-Story Medical Office Space

5803 Chew Ave, Philadelphia, PA 19138

$1,750/Mo

Shared reception, conference, kitchen, and outdoor areas support flexible healthcare practices.

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Professional Office Suite Near Transit

336 N 63rd Street Commercial, Philadelphia, PA 19139

$1,107/Mo

Flexible 2,000-square-foot commercial suite with an open layout, suitable for a range of professional and community uses.

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Medical Office or Retail Space

5922 N Broad St, Philadelphia, PA 19141

$4,850/Mo

Flexible medical office or retail space available for rent at 5922 N Broad St in Philadelphia.

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New Construction Retail Space

1213 Walnut Street, Philadelphia, PA 19107

Contact for pricing

4,586 sqft

Newly built commercial space with prior medical and retail use, positioned near Philadelphia’s major downtown destinations.

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Philadelphia, PA Medical Office Space Lease Rates & Market Statistics

Explore 57 Medical Office Space listings for lease in Philadelphia, PA on Realmo, a commercial real estate exchange covering the Philadelphia area. The current inventory totals 696,714 square feet of properties — an average of ~12,200 SF per listing.

Asking lease rates for Medical Office Space in Philadelphia start at $21.17 SF/Yr, average $25.96 SF/Yr, and reach $42.51 SF/Yr at the top of the market. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings. The local average of $25.96 SF/Yr is 43% above the Pennsylvania state average of $18.14 SF/Yr.

Medical Office Space listings make up 9% of the 602 Office Spaces currently for lease in Philadelphia, with asking rates averaging $25.96 SF/Yr — 24% above the citywide Office Spaces average of $20.96 SF/Yr. Also worth a look for tenants weighing alternatives: Office Units (401 listings) and Office buildings (144 listings) elsewhere in the Philadelphia market.

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Philadelphia, PA Medical Office Space for Lease

10101 ACADEMY Road, Philadelphia, PA 19114

5222 CHESTER Avenue, Philadelphia, PA 19143

5912 RIDGE Avenue, Philadelphia, PA 19128

5912 RIDGE AVENUE, Philadelphia, PA 19128

1802-4 S BROAD Street, Philadelphia, PA 19145

4821 FRANKFORD Avenue, Philadelphia, PA 19124

6713-15 OGONTZ Avenue, Philadelphia, PA 19126

3645 Lancaster Ave, Philadelphia, PA 19104