Philadelphia, PA Medical Office Space for Rent & Lease

Updated: Sep 15

Medical Office with Treatment Rooms

119-123 E LEHIGH Avenue, Philadelphia, PA 19125

$10,000/Mo

0.07 AC lot

17 treatment rooms across two levels
First floor includes 7 treatment rooms with sinks
Second floor includes 10 treatment rooms, with 3 equipped with sinks
3 full bathrooms, including a large ADA‑compliant bathroom
Across from the Temple Hospital Episcopal Campus

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Updated: Aug 15

Bi-Level Office Suite

5222 CHESTER Avenue, Philadelphia, PA 19143

$4,300/Mo

0.10 AC lot

Approximately 2,580 SF of bi‑level commercial space
Four private offices, conference area, open workspaces, and storage closets
Approximately 10.5‑foot ceilings with abundant natural light
Private street‑level entrance with expansive glass frontage along Chester Avenue
Three completed bathrooms, including two ADA‑accessible bathrooms

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Historic Medical Office Space

5912 RIDGE Avenue, Philadelphia, PA 19128

$6,042/Mo

0.22 AC lot

Ground-floor professional space with private offices, reception, kitchenette, and substantial basement storage.

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Two-Level Medical Office Space

119 119-123 E Lehigh Ave, Philadelphia, PA 19125

$10,000/Mo

4,600 sqft

Configured for patient care with reception, treatment rooms, storage, and ADA-compliant restroom facilities.

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Medical Office Space with Exam Rooms

4821 FRANKFORD Avenue, Philadelphia, PA 19124

$5,067/Mo

0.31 AC lot

Configured with reception, examination rooms, offices, storage, and two bathrooms for medical office use.

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Renovated Office Units

1802-4 S BROAD Street, Philadelphia, PA 19145

$4,995/Mo

0.07 AC lot

Professional workspace with private rooms, meeting space, staff kitchen, and accessible entry.

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Live-Work Space with Office

2919 N 22ND Street, Philadelphia, PA 19132

$2,500/Mo

0.03 AC lot

Mixed-use space combines a business setting with the ability to live on site, and is currently configured as a dental office.

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Retail Space with On-Site Parking

1423 Spruce Street First Floor, Philadelphia, PA 19102

$4,950/Mo

3,000 sqft

CMX5 zoning and dedicated parking accompany this first-floor commercial space.

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Ground-Floor Retail Space

626 S 3RD Street, Philadelphia, PA 19147

$3,350/Mo

0.03 AC lot

Masonry commercial space with a private courtyard, lower-level use, and flexible entry options.

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Office Units with Dental Approval

11880 BUSTLETON Avenue, Philadelphia, PA 19116

$900/Mo

Multiple professional suites offer central heating, with utilities and building expenses included in the lease.

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Historic Ground-Floor Medical Office

5912 RIDGE AVENUE, Philadelphia, PA 19128

$6,042/Mo

2,900 sqft

Ground-floor workspace includes private offices, reception, a kitchenette, and one bathroom.

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Medical Office Suite with Exam Rooms

10101 ACADEMY Road, Philadelphia, PA 19114

$8,250/Mo

First-floor layout includes reception, private offices, exam rooms, and restrooms.

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First-Floor Medical Office Space

7516 CITY Avenue, Philadelphia, PA 19151

$14,400/Mo

0.51 AC lot

Ground-level suite in a medical office building with central air, parking, and nearby retail amenities.

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Renovated Medical Office Suite

6713 Ogontz Ave, Philadelphia, PA 19126

$7,000/Mo

3,800 sqft

Move-in-ready medical office space with reception, private offices, conference rooms, and a dedicated treatment or therapy room.

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Medical Office Space with Private Yard

2248 E ALLEGHENY Avenue, Philadelphia, PA 19134

$1,500/Mo

0.03 AC lot

Existing lobby, central air, and adaptable plumbing support professional and healthcare-related occupancy.

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Medical Office with Basement Storage

2428 S BROAD Street, Philadelphia, PA 19145

$2,200/Mo

0.03 AC lot

Existing clinical layout includes central air and additional basement storage.

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Built-Out Office Space

3645 Lancaster Ave, Philadelphia, PA 19104

$2,500/Mo

2,011 sqft

Office unit with basement space and flexibility for retail, fitness, medical, or neighborhood market uses.

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Office Units with Lower Level

1701 POPLAR Street, Philadelphia, PA 19130

$1,200/Mo

0.02 AC lot

Masonry office space offers central HVAC, a first-floor powder room, and additional lower-level area.

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Ground Floor Retail Space

305 N 15th St, Philadelphia, PA 19102

$4,500/Mo

2,480 sqft

Ground floor retail space includes a finished interior and an additional usable basement level.

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First-Floor Commercial Studio with Showroom Windows

1-33 S 3rd St, Philadelphia, PA 19106

$4,400/Mo

1,242 sqft

First-floor commercial studio with large showroom-type windows and strong natural light, positioned near Old City attractions.

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Retail Suite with Lease Availability

493 Domino Ln, Philadelphia, PA 19128

$2,999/Mo

1,700 sqft

Retail suite currently leased to a State Farm Insurance Agency, with lease-up available June 2026 or sooner.

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First-Floor Medical Office Condo

207 N Broad Street, Philadelphia, PA 19107

$22.50 SF/Yr

6,300 sqft

Turn-key medical office condo with convenient parking access and flexible use under CMX-4 zoning.

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Medical Office Space with Upper Unit

2310 E ALLEGHENY AVENUE, Philadelphia, PA 19134

$3,000/Mo

Multi-level commercial space includes treatment rooms, private offices, reception, and flexible upper-floor workspace.

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Two-Level Medical Office

119-123 E LEHIGH AVENUE, Philadelphia, PA 19125

$10,000/Mo

Seventeen treatment rooms support a substantial healthcare or professional practice layout.

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Philadelphia, PA Medical Office Space Lease Rates & Market Statistics

Explore 48 Medical Office Space listings for lease in Philadelphia, PA on Realmo, a commercial real estate exchange covering the Philadelphia area. The current inventory totals 474,068 square feet of properties — an average of ~9,900 SF per listing.

Asking lease rates for Medical Office Space in Philadelphia start at $14.92 SF/Yr, average $23.79 SF/Yr, and reach $42.51 SF/Yr at the top of the market. That's a 3x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. The local average of $23.79 SF/Yr is 27% above the Pennsylvania state average of $18.70 SF/Yr.

Medical Office Space listings make up 10% of the 502 Office Spaces currently for lease in Philadelphia, with asking rates averaging $23.79 SF/Yr — 14% above the citywide Office Spaces average of $20.85 SF/Yr. Also worth a look for tenants weighing alternatives: Office Units (329 listings) and Office buildings (112 listings) elsewhere in the Philadelphia market.

Featured Philadelphia Real Estate Agencies

Realmo connects you with licensed Philadelphia CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

OCF Realty

2054 South St Philadelphia, PA 19146

Phone: 16097801172

www.ocfrealty.com

Maxwell Realty Company Inc

1736 Pine St, Suite 100 Philadelphia, PA 19103

Phone: 12155466000

www.maxwellrealty.com

Houwzer

1435 Walnut Street 3rd Floor Philadelphia, PA 19102

Phone: 12677652080

Philadelphia, PA Medical Office Space for Lease

119-123 E LEHIGH Avenue, Philadelphia, PA 19125

5222 CHESTER Avenue, Philadelphia, PA 19143

5912 RIDGE Avenue, Philadelphia, PA 19128

119 119-123 E Lehigh Ave, Philadelphia, PA 19125

4821 FRANKFORD Avenue, Philadelphia, PA 19124

1802-4 S BROAD Street, Philadelphia, PA 19145

2919 N 22ND Street, Philadelphia, PA 19132

1423 Spruce Street First Floor, Philadelphia, PA 19102