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    Downingtown, PA Medical Office Space for Lease

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    Downingtown Commercial Space For Lease
    $6,000 / Mo
    20,909 SF

    Downingtown Commercial Space For Lease

    45 W Lancaster Ave, Downingtown, PA 19335

    Versatile commercial property in Downingtown, suitable for various businesses.

    • Prime location in Downingtown, near Exton, Chester Springs, West Chester, and Malvern.
    • Flexible zoning suitable for retail, medical, daycare, salon/spa, health club, banquet facility, or warehouse.
    • Expansive open floor plan with HIGH 14' CEILINGS.
    • Approximately 29 parking spaces available.
    • Equipped with TWO LOADING DOCKS and 3‑phase electric.
    Updated: Aug 28, 2025
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    Downingtown Commercial Property For Rent
    $6,000 / Mo

    Downingtown Commercial Property For Rent

    45 W Lancaster Ave, Downingtown, PA 19335

    Versatile commercial property suitable for retail, medical, daycare, or warehouse.

    • Prime location in Downingtown, near Exton, Chester Springs, West Chester, and Malvern.
    • Versatile commercial property with flexible zoning suitable for retail, medical, daycare, salon/spa, health club, banquet facility, or warehouse use.
    • Expansive open floor plan with soaring 14’ ceilings.
    • Approximately 29 parking spaces.
    • Equipped with two loading docks, 3‑phase electric, and HVAC.
    Updated: Aug 28, 2025
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    Medical Office Space Available
    Contact for pricing
    10,500 SF

    Medical Office Space Available

    Medical office space for lease near Thorndale Station.

    3025 Zinn Rd, Thorndale, PA 19372
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    Downingtown Office Space Available
    $18 SF/Yr
    103,880 SF

    Downingtown Office Space Available

    Class A Office Suites, Chester County, PA

    150 Pennsylvania Ave, Downingtown, PA 19335
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    Downingtown Medical Office Building
    Contact for pricing
    68,000 SF

    Downingtown Medical Office Building

    68,000 SF Medical Office, PA

    322 And Boot Rd, Downingtown, PA 19335
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    Based on your search, we've compiled 9 Potential Opportunities for your consideration. Besides 5 Active listings in Downingtown, PA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities

    Explore Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Exton, PA - Fitted Office
    $66,000
    2,614 SF

    Exton, PA - Fitted Office

    2400 SF specialist office space for lease in Exton.

    766 W Lincoln Hwy, Exton, PA 19341
    View details
    Exton Medical Office Space Available
    $16 SF/Yr
    43,040 SF

    Exton Medical Office Space Available

    Prime medical office suites in Chester County, PA.

    460 Creamery Way, Exton, PA 19341
    View details
    Medical/Professional Office Space Available
    $14 SF/Yr
    2,801 SF

    Medical/Professional Office Space Available

    Suites available from 1,000 to 6,202 square feet.

    495 Highlands Blvd, Coatesville, PA
    View details
    Office Space Near Major Routes
    $14 SF/Yr
    15,895 SF

    Office Space Near Major Routes

    Office suites available near Airport Road and Route 30.

    495 Highlands Blvd, Coatesville, PA 19320
    View details

    Downingtown, PA Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Downingtown, PA with 5 listings featured on our commercial real estate exchange. The current inventory includes 5,435,800,162 square feet of properties with an estimated lease value of $21 SF/Yr.

    Estimated lease rates for Medical Office Space in Downingtown, PA begin at $3 SF/Yr, with an average of $10 SF/Yr and extend to $18 SF/Yr.
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    Most Searched ZIP Codes in Downingtown, PA

    • 19335
    • 19372

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