Medical Space

North Syracuse, NY Medical Office Space for Lease

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Liverpool, NY Jamesville, NY East Syracuse, NY
Medical Office Space Available
Updated: Mar 25
Medical Office Space Available

792 North Main Street, North Syracuse, NY 13212

$19 SF/Yr
5,126 sqft · $8,329/Mo
5,126 RSF medical office suite featuring 9 exam rooms, 3 bathrooms, 1 nurses’ station, and 3 administrative offices.
Highly visible location in Village Medical Park, less than one mile from the I‑481/I‑81 interchange.
Ample parking (6.37:1000).
Proximity to Syracuse Hancock International Airport (± 3.1 miles) and downtown Syracuse/major hospitals (±8 miles).
Located near numerous retailers and restaurants including Wegmans, Lowes, The Home Depot, and Price Chopper.
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Turnkey Medical Office Space Available
Updated: Nov 27, 2025
Turnkey Medical Office Space Available

127-29 Seeley Rd, Syracuse, NY 13224

$355,000 SF/Yr
Turnkey medical office space, ready for immediate occupancy.
Prime location with easy access to major routes (690, 81, 481, NYS Thruway).
Professionally renovated building in excellent condition.
Spacious layout with 3000+ sq‑ft, featuring 10 suites, kitchen, office areas, and storage.
Ample parking with 25+ spaces.
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Modern Medical and Office Space
Modern Medical and Office Space

1304 Buckley Road, Syracuse, NY 13212

Contact for pricing
33,548 sqft

Three floors of modern medical and office space for rent.

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Medical Building with Flexible Suites
Medical Building with Flexible Suites

2112 Erie Blvd E, Syracuse, NY

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5,000 sqft

Professional medical building with suites available for lease.

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Downtown Syracuse Office Space Available
Downtown Syracuse Office Space Available

600 E Genesee St, Syracuse, NY

$15 SF/Yr
11,936 sqft · $15,864/Mo

Medical or general office space for lease in Syracuse.

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Based on your search, we've compiled 17 Potential Opportunities for your consideration. Besides 5 Active listings in North Syracuse, NY, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 4 Properties for Sales.

Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Medical Office Suites For Lease
Medical Office Suites For Lease

4000 Medical Center Drive, Fayetteville, NY 13066

Contact for pricing
15,384 sqft

Medical office suites available in Fayetteville, NY.

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East Syracuse Medical Office Conversion
East Syracuse Medical Office Conversion

5062 Brittonfield Parkway, East Syracuse, NY 13057

Contact for pricing
40,625 sqft

Class A medical office conversion near downtown hospitals.

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Fayetteville Office Space For Rent
Fayetteville Office Space For Rent

6800 E Genesee St, Fayetteville, NY

Contact for pricing
40,000 sqft

Office space ideal for medical or professional use near I-690.

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New Development Opportunity in Syracuse
New Development Opportunity in Syracuse

6731 Fly Rd, East Syracuse, NY

Contact for pricing
26,000 sqft

New Class A medical/office or office/warehouse facility for lease.

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Similar Spaces for Sale in North Syracuse, NY

Consider Similar Space for Sale. We found 4 Spaces matching your search parameters.

North Syracuse Medical Office Building
North Syracuse Medical Office Building

105 N Main Street, Syracuse, NY 13212

$400,000
2,244 sqft · 0.23 AC lot

Well-maintained medical office in a high-growth area.

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Multi-Story Office Building
Multi-Story Office Building

717 E Genesee Street, Syracuse, NY 13210

$725,000
6,000 sqft

Six-thousand-square-foot office building with private parking and renovated second-floor space.

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Mixed-Use Building with Dental Practice
Mixed-Use Building with Dental Practice

1500 Grant Blvd and Mayar St, Syracuse, NY

$185,000
2,600 sqft · 0.14 AC lot

2600 SF building with dental practice and apartment.

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Well-Maintained Two-Story Office Building
Well-Maintained Two-Story Office Building

5232 Witz Dr, N Syracuse, NY

$1,695,000
22,867 sqft · 2.08 AC lot

Two-story office building with basement and excellent onsite parking.

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Prime Pad Site for Lease
Prime Pad Site for Lease

9 Old State Rd, Belmont, NH 3220

Contact for pricing

Highly visible 1.74 acre pad site in Belmont, NH.

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Commercial Land Parcel with Utilities
Commercial Land Parcel with Utilities

2585 Maple Lane, Pittsburgh, PA 15241

$50,000 SF/Yr

Level, fully serviced commercial parcel with approvals in place and signage permitted up to 20 sq ft.

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Beaumont Centre Outparcel Opportunity
Beaumont Centre Outparcel Opportunity

3199 Beaumont Centre Circle, Lexington, KY 40513

Contact for pricing

Outparcel opportunity in established shopping center for ground lease.

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Prime Lexington Outlot Opportunity
Prime Lexington Outlot Opportunity

3330 Partner Place, Lexington, KY 40503

Contact for pricing

Outlot for ground lease or build-to-suit in South Lexington.

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North Syracuse, NY Medical Office Space Market Trends and Statistics

Explore Medical Office Space leasing options in North Syracuse, NY with 5 listings featured on our commercial real estate exchange. The current inventory includes 17,062 square feet of properties with an estimated lease value of $35 SF/Yr.

Estimated lease rates for Medical Office Space in North Syracuse, NY begin at $15 SF/Yr, with an average of $17 SF/Yr and extend to $19 SF/Yr.
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