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    Poplar Bluff, MO Medical Office Space for Lease

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    6,500 SF Commercial Space
    $6,000 / Mo
    31,363 SF

    6,500 SF Commercial Space

    3999 Highway Pp, Poplar Bluff, MO 63901

    6,500 SF commercial space for lease in Poplar Bluff, MO.

    • Expansive 6,500 sq ft commercial space.
    • Versatile open layout suitable for various businesses.
    • Prime location with ample parking.
    • Previously utilized as a medical rehabilitation facility.
    • Relatively new construction (Year Built: 2012).
    Updated: Oct 15, 2025
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    Based on your search, we've compiled 6 Potential Opportunities for your consideration. Besides 1 Active listings in Poplar Bluff, MO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 1 Properties for Sales.

    Explore Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Jonesboro Medical Office Space
    $15 SF/Yr
    15,000 SF

    Jonesboro Medical Office Space

    Prime 15,000 SF Medical Office in Jonesboro, AR

    4212 Johnson Ave, Jonesboro, AR 72401
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    Hilltop Medical/Office Space For Lease
    $18 SF/Yr
    6,600 SF

    Hilltop Medical/Office Space For Lease

    Jonesboro, AR: 3,600 SF Available

    3637 Johnson Ave, Jonesboro, AR 72401
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    Medical Office in Strawberry Hills
    $6,500 / Mo

    Medical Office in Strawberry Hills

    Medical office space for rent in a booming area.

    4645 Village Square Dr, Paducah, KY 42001
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    Paducah Office Space For Lease
    $9 SF/Yr

    Paducah Office Space For Lease

    9,067± SF office space in the heart of Lone Oak.

    67 Lakeview Dr, Paducah, KY 42001
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    Explore Similar Spaces for Sale in Poplar Bluff, MO

    Consider Similar Space for Sale. We found 1 Spaces in Nearby Locations matching your search parameters.

    Value-Add Medical Office Building
    $299,900

    Value-Add Medical Office Building

    9,600 SF medical office building for sale as-is.

    2865 James Blvd, Poplar Bluff, MO 63901
    View details

    Poplar Bluff, MO Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Poplar Bluff, MO with 2 listings featured on our commercial real estate exchange. The current inventory includes 1,366,180,958 square feet of properties with an estimated lease value of $2 SF/Yr.

    Estimated lease rates for Medical Office Space in Poplar Bluff, MO begin at $2 SF/Yr, with an average of $2 SF/Yr and extend to $2 SF/Yr.
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    Most Searched ZIP Codes in Poplar Bluff, MO

    • 63901

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