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    Poplar Bluff, MO
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    Poplar Bluff, MO Medical Centers for Sale

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    Broseley, MO Williamsville, MO Neelyville, MO
    Versatile Building in Poplar Bluff
    $325,000
    12,351 SF
    Versatile Building in Poplar Bluff

    338 Hazel St, Poplar Bluff, MO 63901

    12351 SF building suitable for various purposes in Poplar Bluff.
    • Large 12,351 sq ft building suitable for various uses
    • Updated with a new roof over the gym, newer heat and air units, new carpet, and fresh paint
    • Includes a 67x35 sanctuary with loft and a 46x37 gym
    • Features 9 classroom‑sized rooms, 5‑8 office/storage rooms, and 3 restrooms
    • Equipped with 2 working kitchens
    Updated: Jun 10
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    Poplar Bluff Ambulance Base
    $937,500
    Poplar Bluff Ambulance Base

    414 N 5th St, Poplar Bluff, MO 63901

    Mission-critical ambulance base in central Poplar Bluff, Missouri.
    • Mission‑critical ambulance base with exclusive county contract.
    • Attractive NN lease structure shifts CAMs, taxes, insurance, utilities, and routine repairs to the tenant.
    • Strategically located in the center of town with strong visibility and accessibility.
    • Secured by 2% annual rent increases beginning January 1, 2029.
    • Custom facility includes beds, bathrooms, laundry, backup generators, and is HIPPA compliant.
    Updated: Nov 25, 2025
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    Based on your search, we've compiled 15 Potential Opportunities for your consideration. Besides 2 Active listings in Poplar Bluff, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 5 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Ambulatory Surgery Center Investment Opportunity
    $8,050,000
    13,650 SF
    Ambulatory Surgery Center Investment Opportunity

    Single-tenant surgery center near St. Francis Medical Center for sale.

    3241 Percy Drive, Cape Girardeau, MO 63701

    View details
    Versatile Commercial Building on 1.9 Acres
    $2,900,000
    13,458 SF
    Versatile Commercial Building on 1.9 Acres

    All-brick commercial building with abundant parking and multiple use opportunities.

    1429 N Mount Auburn Road, Cape Girardeau, MO 63701

    View details
    Commercial Development Site
    $229,900
    2.90 Acres
    Commercial Development Site

    2.9-acre commercial site at a heavily used highway intersection offering flexible retail, office, or medical development options.

    Bill Virdon Boulevard, West Plains, MO 65775

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    Commercial Corner Land Lot
    $79,000
    1.00 Acre
    Commercial Corner Land Lot

    Approximately 1-acre corner lot positioned at a major West Plains intersection with multiple development options.

    Bill Virdon Boulevard, West Plains, MO 65775

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    72.72 Acres in Brownsville, TN
    $890,000
    72.72 Acres
    72.72 Acres in Brownsville, TN

    Large parcel in high-traffic area with utilities and hospital proximity.

    N Washington Avenue, Brownsville, TN 38012

    View details
    Arlington Land For Sale
    $9,900,000
    27.35 Acres
    Arlington Land For Sale

    27.35 acres of mixed-use development land in Arlington, TN.

    MILTON WILSON Blvd, Arlington, TN 38002

    View details
    Prime Commercial Land on Highway
    $1,490,000
    4.40 Acres
    Prime Commercial Land on Highway

    4.4-acre commercial land with highway frontage near future developments.

    Highway 54, Osage Beach, MO 65065

    View details
    Prime Commercial Land on Highway
    $1,490,000
    4.40 Acres
    Prime Commercial Land on Highway

    4.4-acre commercial land with highway frontage near future developments.

    Hwy 54, Osage Beach, MO 65065

    View details

    Off-Market Properties in Poplar Bluff, MO

    Consider similar Off-Market properties in Poplar Bluff, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    Debbie Ln
    MEDICAL BUILDING
    2,727 SF Lot: 2.96 Acres
    Value Estimation by Request

    Debbie Ln, Poplar Bluff, MO 63901

    View details
    3150 Warrior Ln
    MEDICAL BUILDING
    9,053 SF
    Value Estimation by Request

    3150 Warrior Ln, Poplar Bluff, MO 63901-8686

    View details
    2704 Debbie Ln, Unit 2711
    MEDICAL BUILDING
    23,447 SF Lot: 18.81 Acres
    Value Estimation by Request
    Unit 2711

    2704 Debbie Ln, Poplar Bluff, MO 63901-2650

    View details
    2698 Debbie Ln
    MEDICAL BUILDING
    6,606 SF Lot: 3.15 Acres
    Value Estimation by Request

    2698 Debbie Ln, Poplar Bluff, MO 63901-2629

    View details
    Poplar Bluff, MO 63901
    MEDICAL BUILDING
    4,460 SF Lot: 3.40 Acres
    Value Estimation by Request

    Poplar Bluff, MO 63901

    View details

    Poplar Bluff, MO Medical Centers Market Trends and Statistics

    Explore 7 medical centers for sale in Poplar Bluff, MO on our real estate platform. These investment opportunities span a total of 12,351 square feet of properties for sale, with an estimated market value of $325,000.

    Sale prices for medical buildings in Poplar Bluff, MO start at $325,000, averaging $325,000, and reaching up to $325,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Medical centers 2
    Assisted living facilities 1
    Rehabilitation centers 1
    Spa & wellness properties 1

    Demographics Overview

    Population 35K
    Population Growth (5Y) -0.6%
    Median Household Income $49,979
    College Educated 11.1%

    High-Yield Neighborhoods for Investment

    Identify Poplar Bluff submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    63901 $631.3K

    Total CRE Inventory on Market (SF)

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