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Lancaster County, PA Live-work Space for Sale

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Historic Mixed-Use Commercial Building
$565,000
0.06 Acres

Historic Mixed-Use Commercial Building

22 S 2ND Street, Columbia, PA 17512

Unique property blending historic charm with modern convenience in downtown Columbia.

  • Prime downtown location suitable for a variety of commercial and residential uses.
  • Unique live‑work opportunity with a second‑floor living space and small, fenced‑in yard.
  • Historic building (built in 1900) featuring original architectural details, including cantilevered storefront display windows and intricate brickwork.
  • Updated features include refinished wood floors and custom hand‑blown glass light fixtures.
  • Currently operating as a successful business with existing infrastructure for retail, event space, and food service.
Updated: Jan 6
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Based on your search, we've compiled 79 Potential Opportunities for your consideration. Besides 1 Active listings in Lancaster County, PA, we suggest exploring several alternatives: similar 78 Off-Market properties to explore as potential leads

Explore Off-Market Properties in Lancaster County, PA

Consider similar Off-Market properties in Lancaster County, PA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

875 Main St

875 Main St

OFFICE/RESIDENTIAL (MIXED USE) • 17,500 SF
Value Estimation
$1,710,000
875 Main St, New Holland, PA 17557-9224
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315 Star Rd

315 Star Rd

OFFICE/RESIDENTIAL (MIXED USE) • 5,070 SF
Value Estimation
$595,000
315 Star Rd, Strasburg, PA 17579-9603
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827 Spruce St

827 Spruce St

OFFICE/RESIDENTIAL (MIXED USE) • 3,375 SF
Value Estimation by Request
827 Spruce St, Elizabethtown, PA 17022-2757
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9 Lime St

9 Lime St

OFFICE/RESIDENTIAL (MIXED USE) • 11,162 SF
Value Estimation by Request
9 Lime St, Quarryville, PA 17566
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182 Main St

182 Main St

OFFICE/RESIDENTIAL (MIXED USE) • 900 SF
Value Estimation by Request
182 Main St, Leola, PA 17540
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759 Mnr St

759 Mnr St

OFFICE/RESIDENTIAL (MIXED USE) • 762 SF
Value Estimation by Request
759 Mnr St, Lancaster, PA 17603-5128
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Elizabethtown Rd

Elizabethtown Rd

OFFICE/RESIDENTIAL (MIXED USE) • 3.00 Acres
Value Estimation by Request
Elizabethtown Rd, Manheim, PA 17545
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317 State St

317 State St

OFFICE/RESIDENTIAL (MIXED USE) • 900 SF
Value Estimation by Request
317 State St, Ephrata, PA 17522-2236
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39 Main St

39 Main St

OFFICE/RESIDENTIAL (MIXED USE) • 9,498 SF
Value Estimation
$1,125,000
39 Main St, Ephrata, PA 17522-2850
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842 Hanover St

842 Hanover St

OFFICE/RESIDENTIAL (MIXED USE) • 18,272 SF
Value Estimation
$2,855,000
842 Hanover St, Elizabethtown, PA 17022-1303
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245 King St

245 King St

OFFICE/RESIDENTIAL (MIXED USE) • 4,192 SF
Value Estimation
$820,000
245 King St, Lancaster, PA 17602-2960
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202 James St

202 James St

OFFICE/RESIDENTIAL (MIXED USE) • 9,724 SF
Value Estimation
$1,565,000
202 James St, Lancaster, PA 17603-2910
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19 4th St

19 4th St

OFFICE/RESIDENTIAL (MIXED USE) • 2,192 SF
Value Estimation by Request
19 4th St, Columbia, PA 17512-1118
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58 Frederick St

58 Frederick St

OFFICE/RESIDENTIAL (MIXED USE) • 3,032 SF
Value Estimation
$500,000
58 Frederick St, Millersville, PA 17551-1927
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123 Market St

123 Market St

OFFICE/RESIDENTIAL (MIXED USE) • 1,407 SF
Value Estimation by Request
123 Market St, Marietta, PA 17547-1448
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13 Martic Frg Loop

13 Martic Frg Loop

OFFICE/RESIDENTIAL (MIXED USE) • 4,512 SF
Value Estimation by Request
13 Martic Frg Loop, Pequea, PA 17565
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23 Market St

23 Market St

OFFICE/RESIDENTIAL (MIXED USE) • 2,908 SF
Value Estimation by Request
23 Market St, Elizabethtown, PA 17022-2308
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305 Locust St

305 Locust St

OFFICE/RESIDENTIAL (MIXED USE) • 2,452 SF
Value Estimation by Request
305 Locust St, Columbia, PA 17512-1120
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710 Columbia Ave

710 Columbia Ave

OFFICE/RESIDENTIAL (MIXED USE) • 1,567 SF
Value Estimation by Request
710 Columbia Ave, Lancaster, PA 17603-3635
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443 Clay St

443 Clay St

OFFICE/RESIDENTIAL (MIXED USE) • 2,160 SF
Value Estimation by Request
443 Clay St, Lancaster, PA 17602-2153
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903 Wheatland Ave

903 Wheatland Ave

OFFICE/RESIDENTIAL (MIXED USE) • 3,134 SF
Value Estimation
$725,000
903 Wheatland Ave, Lancaster, PA 17603-3134
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435 Beechdale Rd

435 Beechdale Rd

OFFICE/RESIDENTIAL (MIXED USE) • 1,351 SF
Value Estimation by Request
435 Beechdale Rd, Bird In Hand, PA 17505-9789
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53 Main St

53 Main St

OFFICE/RESIDENTIAL (MIXED USE) • 5,512 SF
Value Estimation
$640,000
53 Main St, Lititz, PA 17543-1941
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Lancaster County, PA Live-Work Space Investment Opportunities Market Analysis

Explore 79 live-work space for sale in Lancaster County, PA on our real estate platform. These investment opportunities span a total of 5,528,201 square feet of properties for sale, with an estimated market value of $34,140,000.

Sale prices for live-work properties in Lancaster County, PA start at $105,000, averaging $588,620, and reaching up to $3,175,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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