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Lancaster County, PA Live-work Space for Sale

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Historic Mixed-Use Commercial Building
$649,900
0.06 Acres

Historic Mixed-Use Commercial Building

22 S 2Nd St, Columbia, PA 17512

Unique property blending historic charm with modern convenience.

  • Prime downtown location suitable for commercial and/or residential use
  • Versatile property currently operating as a retail store, event space, and coffee shop with a second‑floor living space
  • Historic building (built in 1900) with unique architectural details, including cantilevered display windows and distinctive brickwork
  • Updated features include refinished wood floors and custom hand‑blown glass light fixtures
  • Full bathroom on every floor and a full kitchen on the second floor
Updated: Feb 6
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Based on your search, we've compiled 79 Potential Opportunities for your consideration. Besides 1 Active listings in Lancaster County, PA, we suggest exploring several alternatives: similar 78 Off-Market properties to explore as potential leads

Explore Off-Market Properties in Lancaster County, PA

Consider similar Off-Market properties in Lancaster County, PA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

142 King St

142 King St

OFFICE/RESIDENTIAL (MIXED USE) • 0.09 Acres
Value Estimation by Request
142 King St, Lancaster, PA 17602-2832
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544 Main St

544 Main St

OFFICE/RESIDENTIAL (MIXED USE) • 840 SF
Value Estimation by Request
544 Main St, Mount Joy, PA 17552-1122
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19 4th St

19 4th St

OFFICE/RESIDENTIAL (MIXED USE) • 2,192 SF
Value Estimation by Request
19 4th St, Columbia, PA 17512-1118
View details
13 Martic Frg Loop

13 Martic Frg Loop

OFFICE/RESIDENTIAL (MIXED USE) • 4,512 SF
Value Estimation by Request
13 Martic Frg Loop, Pequea, PA 17565
View details
39 Main St

39 Main St

OFFICE/RESIDENTIAL (MIXED USE) • 9,498 SF
Value Estimation
$1,125,000
39 Main St, Ephrata, PA 17522-2850
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930 Pointview Ave

930 Pointview Ave

OFFICE/RESIDENTIAL (MIXED USE) • 4,072 SF
Value Estimation
$675,000
930 Pointview Ave, Ephrata, PA 17522-2399
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170 New Hvn St

170 New Hvn St

OFFICE/RESIDENTIAL (MIXED USE) • 82,910 SF
Value Estimation by Request
170 New Hvn St, Mount Joy, PA 17552-2226
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312 Christian St

312 Christian St

OFFICE/RESIDENTIAL (MIXED USE) • 2,001 SF
Value Estimation by Request
312 Christian St, Lancaster, PA 17602-4902
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820 Christian St

820 Christian St

OFFICE/RESIDENTIAL (MIXED USE) • 10,066 SF
Value Estimation
$1,220,000
820 Christian St, Lancaster, PA 17602
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550 New Holland Ave

550 New Holland Ave

OFFICE/RESIDENTIAL (MIXED USE) • 9,862 SF
Value Estimation
$2,400,000
550 New Holland Ave, Lancaster, PA 17602-2184
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1904 Mine Rd

1904 Mine Rd

OFFICE/RESIDENTIAL (MIXED USE) • 448 SF
Value Estimation by Request
1904 Mine Rd, Paradise, PA 17562-9757
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169 4th St

169 4th St

OFFICE/RESIDENTIAL (MIXED USE) • 1,489 SF
Value Estimation by Request
169 4th St, Columbia, PA 17512-1442
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816 Prince St

816 Prince St

OFFICE/RESIDENTIAL (MIXED USE) • 94,068 SF
Value Estimation
$24,970,000
816 Prince St, Lancaster, PA 17603-2743
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905 Queen St

905 Queen St

OFFICE/RESIDENTIAL (MIXED USE) • 4,000 SF
Value Estimation
$575,000
905 Queen St, Lancaster, PA 17603-5819
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305 Locust St

305 Locust St

OFFICE/RESIDENTIAL (MIXED USE) • 2,452 SF
Value Estimation by Request
305 Locust St, Columbia, PA 17512-1120
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119 Chestnut St

119 Chestnut St

OFFICE/RESIDENTIAL (MIXED USE) • 3,690 SF
Value Estimation
$545,000
119 Chestnut St, Lancaster, PA 17602-2703
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443 Clay St

443 Clay St

OFFICE/RESIDENTIAL (MIXED USE) • 2,160 SF
Value Estimation by Request
443 Clay St, Lancaster, PA 17602-2153
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520 Rte 897

520 Rte 897

OFFICE/RESIDENTIAL (MIXED USE) • 2,800 SF
Value Estimation
$680,000
520 Rte 897, Reinholds, PA 17569-9800
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8 Main St

8 Main St

OFFICE/RESIDENTIAL (MIXED USE) • 3,350 SF
Value Estimation
$645,000
8 Main St, Strasburg, PA 17579-1481
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315 Star Rd

315 Star Rd

OFFICE/RESIDENTIAL (MIXED USE) • 5,070 SF
Value Estimation
$595,000
315 Star Rd, Strasburg, PA 17579-9603
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600 Richmond Dr

600 Richmond Dr

OFFICE/RESIDENTIAL (MIXED USE) • 4,300 SF
Value Estimation
$1,335,000
600 Richmond Dr, Lancaster, PA 17601-8812
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224 Locust St

224 Locust St

OFFICE/RESIDENTIAL (MIXED USE) • 16,426 SF
Value Estimation
$1,695,000
224 Locust St, Columbia, PA 17512-1111
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323 Crystal St

323 Crystal St

OFFICE/RESIDENTIAL (MIXED USE) • 576 SF
Value Estimation by Request
323 Crystal St, Lancaster, PA 17603-5179
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Lancaster County, PA Live-Work Space Investment Opportunities Market Analysis

Explore 79 live-work space for sale in Lancaster County, PA on our real estate platform. These investment opportunities span a total of 5,528,201 square feet of properties for sale, with an estimated market value of $34,224,900.

Sale prices for live-work properties in Lancaster County, PA start at $105,000, averaging $590,084, and reaching up to $3,175,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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