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    Charleston, SC Commercial Real Estate for Lease

    229 results
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    Downtown Charleston
    Contact for pricing

    Downtown Charleston

    Discover many ways to work your way in Downtown Charleston

    170 Floors, Charleston, SC 29401
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    Charleston Historic District Office Space
    $22 SF/Yr

    Charleston Historic District Office Space

    2 Cumberland St, Charleston, SC 29401

    Renovated office suites with harbor views in historic Charleston.

    • Rare views of Charleston Harbor, Ravenel Bridge, US Customs House, and USS Yorktown.
    • Newly renovated suites with modern finishes ready for immediate occupancy.
    • Located in the historic district of Charleston's peninsula.
    • Open floorplans provide functional versatility.
    • Suites available on the 2nd and 3rd floors, each with 4,204 RSF.
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    Downtown Charleston Freestanding Building
    $29 SF/Yr

    Downtown Charleston Freestanding Building

    276 East Bay St, Charleston, SC 29401

    Freestanding building in historic downtown Charleston for lease.

    • Prime location in historic downtown Charleston, near East Bay Harris Teeter and Ansonborough Inn.
    • ±14,518 SF freestanding building with flexible use options: retail, office, or restaurant.
    • Rare on‑site parking with 38 spaces.
    • High traffic volume: 28,300 VPD on East Bay (SCDOT 2024) and high walkability score of 83%.
    • Proximity to Union Pier mixed‑use development and future College of Charleston Business School.
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    James Island Office Space Available
    $20 SF/Yr

    James Island Office Space Available

    Office space for lease in a convenient Charleston location.

    125 Wappoo Creek Dr, Charleston, SC 29412
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    Prime Retail Space on George
    $45 SF/Yr

    Prime Retail Space on George

    Retail space for lease in downtown Charleston near King Street.

    51 George St, Charleston, SC 29401
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    Whole Foods Anchored Shopping Center
    Contact for pricing

    Whole Foods Anchored Shopping Center

    Premier shopping center in West Ashley with high-traffic location.

    1133 Savannah Hwy, Charleston, SC 29407
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    Charleston Flex Retail Space
    Contact for pricing

    Charleston Flex Retail Space

    Flex retail space in established commercial corridor with high traffic.

    1436 Meeting Street Rd, Charleston, SC 29405
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    Charleston Historic District Office Space
    $22 SF/Yr
    16,816 SF

    Charleston Historic District Office Space

    Renovated office suites with harbor views in Charleston's historic district.

    2 Cumberland St, Charleston, SC 29401
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    Retail Space in James Island
    $38 SF/Yr

    Retail Space in James Island

    Retail space for lease in a high-traffic shopping center.

    1739 Maybank Hwy, Charleston, SC 29412
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    Daniel Island Office/Medical Opportunity
    Contact for pricing
    3,047 SF

    Daniel Island Office/Medical Opportunity

    Office/Medical space in Publix-anchored Daniel Island shopping center.

    162 Seven Farms Dr, Charleston, SC 29492
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    King Street Retail Space Available
    Contact for pricing

    King Street Retail Space Available

    Prime retail space in downtown Charleston's shopping corridor.

    338-A King Street Ext, Charleston, SC 29401
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    Prime Retail Space on King
    $75 SF/Yr

    Prime Retail Space on King

    High-profile retail space in downtown Charleston near Charleston Place.

    229 King St, Charleston, SC 29401
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    Class A Office Space Available
    $22 SF/Yr

    Class A Office Space Available

    Class A office suite for lease in growing Daniel Island/Cainhoy.

    1951 Clements Ferry Rd, Charleston, SC 29492
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    Downtown Charleston Freestanding Building
    $29 SF/Yr
    14,518 SF

    Downtown Charleston Freestanding Building

    Freestanding building in historic downtown Charleston with on-site parking.

    276 East Bay St, Charleston, SC 29401
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    Wappoo Creek Office Space Available
    $20 SF/Yr
    2,944 SF

    Wappoo Creek Office Space Available

    Office space for lease in a convenient Charleston location.

    125 Wappoo Creek Dr, Charleston, SC 29412
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    Daniel Island Office Space Available
    $32 SF/Yr
    3,975 SF

    Daniel Island Office Space Available

    Second-floor office suite in Daniel Island's Town Center.

    115 River Landing Dr, Charleston, SC 29492
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    Class A Office Sublease
    $38 SF/Yr
    10,499 SF

    Class A Office Sublease

    Class A office space available for sublease in Charleston, SC.

    100 Calhoun St, Charleston, SC 29401
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    Prime Retail Space in Charleston
    $38 SF/Yr

    Prime Retail Space in Charleston

    Street-front retail with high ceilings, free parking, great visibility.

    601 Meeting Street Rd, Charleston, SC 29403
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    Riverland Terrace Retail Opportunity
    Contact for pricing

    Riverland Terrace Retail Opportunity

    Retail space in high-traffic area near downtown Charleston.

    2040 Maybank Hwy, Charleston, SC 29412
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    Renovated Retail/Office/Flex Space Available
    $22 SF/Yr
    20,361 SF

    Renovated Retail/Office/Flex Space Available

    Newly renovated space ideal for retail, office, and flex users.

    5640 Rivers Ave, Charleston, SC 29406
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    Prime Retail Space on King
    Contact for pricing

    Prime Retail Space on King

    Retail space in Charleston's premier shopping and dining area.

    370 King St, Charleston, SC 29401
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    Charleston Warehouse/Storage Facility For Lease
    $10 SF/Yr

    Charleston Warehouse/Storage Facility For Lease

    Warehouse/storage facility in excellent location on Charleston's upper peninsula.

    1795 King Street Ext, Charleston, SC 29405
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    Prime Retail Space on George
    $45 SF/Yr
    3,641 SF

    Prime Retail Space on George

    Retail space for lease in downtown Charleston near King Street.

    51 George St, Charleston, SC 29401
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    West Ashley Retail Space Available
    $18 SF/Yr

    West Ashley Retail Space Available

    Retail space for lease in West Island Center.

    2049 Savannah Hwy, Charleston, SC 29407
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    Charleston, SC Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Charleston, SC with 228 listings featured on our commercial real estate exchange. The current inventory includes 87,605,955,360 square feet of properties with an estimated lease value of $80,747.

    Estimated lease rates for Commercial real estate in Charleston, SC begin at $2 SF/Yr, with an average of $690 /Mo and extend to $45,000.
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    Browse Commercial real estate for Lease Near Charleston, SC

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