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    Cape Girardeau, MO Office Buildings for Sale

    8 results
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    Updated Office Building For Sale
    $350,000
    4,000 SF

    Updated Office Building For Sale

    824 Independence Street, Cape Girardeau, MO 63703

    Well-maintained office building with high visibility and ample parking.

    • High daily traffic count on Independence
    • Excellent visibility
    • Ample on‑site parking
    • Well‑maintained and updated office building
    • Suitable for a variety of professional or service‑based businesses
    Updated: Mar 20
    View details
    Leased Office Building For Sale
    $500,000
    7,140 SF

    Leased Office Building For Sale

    2711 Thomas Drive, Cape Girardeau, MO 63701

    Two-story office building with 21 units and parking.

    • Leased office building providing immediate income for investors.
    • Prime location just off North Kingshighway.
    • 21 units, including lower‑level garage space.
    • Parking lot with approximately 20 spaces.
    • Option to increase parking capacity by adding angled parking in the rear.
    Updated: Sep 17, 2025
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    Renovated Commercial Space in Cape Girardeau
    $239,900
    2,937 SF

    Renovated Commercial Space in Cape Girardeau

    Renovated commercial space with high potential in a prime location.

    230 N Sprigg Street, Cape Girardeau, MO 63701
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    Downtown Office Building For Sale
    $899,900
    13,694 SF

    Downtown Office Building For Sale

    13,694 SF office building in historic downtown Cape Girardeau.

    18 N. Main, Cape Girardeau, MO 63701
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    Two-Level Office Building For Sale
    $815,000
    9,857 SF

    Two-Level Office Building For Sale

    9,857 SF office building with multiple offices and restrooms.

    10 Doctors Park, Cape Girardeau, MO 63703
    View details
    Renovated Commercial Building on Sprigg
    $239,900
    2,937 SF

    Renovated Commercial Building on Sprigg

    Renovated commercial space with high visibility and income potential.

    230 N Sprigg Street, Cape Girardeau, MO 63701
    View details
    Professional Office Complex For Sale
    Contact for pricing

    Professional Office Complex For Sale

    Professional office complex with parking near I-55, hotels, restaurants.

    240-276 S. Mount Auburn Road, Cape Girardeau, MO 63703
    View details
    13,694 SF Single-Level Office Building
    $899,900
    13,694 SF

    13,694 SF Single-Level Office Building

    Single-level office building suitable for various uses and businesses.

    18 Main St, Cape Girardeau, MO 63701
    View details
    Based on your search, we've compiled 16 Potential Opportunities for your consideration. Besides 8 Active listings in Cape Girardeau, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities, plus 4 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Sikeston Commercial Building Investment Opportunity
    $979,500
    11,000 SF

    Sikeston Commercial Building Investment Opportunity

    High-visibility commercial building with income and upside potential.

    808 E Wakefield Ave, Sikeston, MO 63801
    View details
    Remodeled IT Building on Highway
    $430,000
    0.20 Acres

    Remodeled IT Building on Highway

    Remodeled office building with high visibility and technological infrastructure.

    608 EASTGATE Drive, Carbondale, IL 62901
    View details
    Commercial Building in High Traffic
    $400,000
    7,100 SF

    Commercial Building in High Traffic

    7100 sq ft commercial building in high traffic area.

    1218 Linn St, Sikeston, MO 63801
    View details
    Executive Offices in Cedar Court
    $359,900
    7,786 SF

    Executive Offices in Cedar Court

    Modern, updated executive offices in premier office park.

    1160 CEDAR Court, Carbondale, IL 62901
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Land in Central Location
    Contact for pricing

    Commercial Land in Central Location

    1.2 acres suitable for retail or office development.

    1749 Independence, Cape Girardeau, MO 63701
    View details
    Commercial Lot with High Visibility
    $99,900

    Commercial Lot with High Visibility

    Commercial lot with 190' frontage in high-traffic location.

    2010 William, Cape Girardeau, MO 63703
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    Commercial Building Lot For Sale
    $149,500

    Commercial Building Lot For Sale

    Commercial lot with 190' frontage and city services.

    2010 William, Cape Girardeau, MO 63703
    View details
    Commercial Condominiums in Historic Building
    $129,900
    4,300 SF

    Commercial Condominiums in Historic Building

    Four commercial condominiums in downtown Cape Girardeau.

    937 Broadway Street, Cape Girardeau, MO 63701
    View details

    Cape Girardeau, MO Office Buildings Investment Opportunities Market Analysis

    Explore 8 office buildings for sale in Cape Girardeau, MO, showcased through 8 active listings on our real estate platform. These investment opportunities span a total of 50,442 square feet of properties for sale, with an estimated market value of $1,089,900.

    Sale prices for office properties in Cape Girardeau, MO start at $239,900, averaging $363,300, and reaching up to $500,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Most Searched ZIP Codes in Cape Girardeau, MO

    • 63701
    • 63703

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