Add Listing
    For Sale
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Property Types
    • Retail
    • Office
    • Residential Income
    • Restaurants
    • Industrial
    • Mixed-Use
    • Hospitality
    • Health Care
    • Sports & Entertainment
    • Land
    • Agricultural
    • Specialty
    Price
    Price range
    $
    $
    Size
    Property size / sq.ft.
    AI Search

    Saint Helena, SC Commercial Real Estate for Sale

    118 results
    List
    Map
    Harbor Island Commercial Opportunity
    $1,950,000
    0.93 Acres

    Harbor Island Commercial Opportunity

    2111 Sea Island Pkwy, Saint Helena Island, SC 29920

    Restaurant and roadside marketplace near Fripp and Hunting Islands.

    • Prime location on Sea Island Parkway, easy access to Fripp and Hunting Island
    • Established restaurant with commercial kitchen, bar, expansive indoor/outdoor seating
    • Roadside marketplace ideal for selling fresh seafood, fishing gear, and tackle
    • Large acreage (approx. one acre with three separate lots) offering flexibility for future development
    • Oyster wash‑down station, licensed and connected to water
    Updated: Feb 20
    View details
    St. Helena Island Commercial Property
    $1,450,000
    6.98 Acres

    St. Helena Island Commercial Property

    1760 Sea Island Pkwy, Saint Helena Island, SC 29920

    Commercial property in the heart of St. Helena Island.

    • Successful restaurant currently occupies the property, providing immediate income potential.
    • Zoned C4 Community Center Mixed Use, allowing for diverse development opportunities.
    • Acreage out back offers significant potential for expansion and future development.
    • Completely renovated with new metal roof, flooring, paint, and updated bathrooms.
    • Includes an outdoor covered porch, enhancing the property's appeal.
    Updated: Jan 16
    View details
    Versatile Commercial Property on Highway 21
    $595,000
    3,520 SF

    Versatile Commercial Property on Highway 21

    Mixed-use property with high visibility and flexible layout.

    2123 Sea Island Pkwy, Saint Helena Island, SC 29920
    View details
    St. Helena Island Mixed-Use Land
    $429,000
    3.90 Acres

    St. Helena Island Mixed-Use Land

    3.9 acre mixed-use land with development potential.

    785 Sea Island Pkwy, Saint Helena Island, SC 29920
    View details
    Highway Frontage Land Parcel
    $429,000
    3.90 Acres

    Highway Frontage Land Parcel

    Land with flexible zoning and high visibility on Sea Island.

    785 Sea Island Pkwy, Saint Helena Island, SC 29920
    View details
    St. Helena Island Commercial Land
    $299,000
    1.70 Acres

    St. Helena Island Commercial Land

    1.7 acres of commercial land with highway frontage.

    1860 Sea Island Pkwy, Saint Helena Island, SC 29920
    View details
    St. Helena Island Wooded Land
    $180,000
    5.00 Acres

    St. Helena Island Wooded Land

    Five-acre wooded parcels available on Seaside Road, St. Helena Island.

    1751 Seaside Rd, Saint Helena Island, SC 29920
    View details
    St. Helena Island Land Opportunity
    $175,000
    7.17 Acres

    St. Helena Island Land Opportunity

    7.17 acres on St. Helena Island, South Carolina.

    161 Carolina Cswy, Saint Helena Island, SC 29920
    View details
    St. Helena Island Agricultural Land
    $225,000
    6.90 Acres

    St. Helena Island Agricultural Land

    6.9-acre agricultural land near Beaufort and Hunting Island State Park.

    1344 Sea Island Pkwy, Saint Helena Island, SC 29920
    View details
    Waterfront Equestrian Estate Opportunity
    $2,299,900

    Waterfront Equestrian Estate Opportunity

    30-acre waterfront property with equestrian facilities on St. Helena Island.

    71 Tropicana Rd, Saint Helena Island, SC 29920
    View details
    30-Acre Waterfront Estate
    $2,299,900
    30.00 Acres

    30-Acre Waterfront Estate

    30-acre waterfront estate on St. Helena Island, currently an equestrian center.

    71 Tropicana Rd, Saint Helena Island, SC 29920
    View details
    St. Helena Island Land Parcel
    $575,000
    10.76 Acres

    St. Helena Island Land Parcel

    10.76 acre property near beaches and boat landings.

    272 Dulamo Rd, Saint Helena Island, SC 29920
    View details
    9 Acres on St. Helena Island
    $400,000
    9.00 Acres

    9 Acres on St. Helena Island

    Scenic Lowcountry property with wooded areas on St. Helena Island.

    278 Dulamo Rd, Saint Helena Island, SC 29920
    View details
    St. Helena Island Land Tract
    $149,000
    8.92 Acres

    St. Helena Island Land Tract

    Large land tract with high and dry sections on St. Helena.

    1236 Seaside Rd, Saint Helena Island, SC 29920
    View details
    7 Acres Tidal Creek Land
    $375,000
    7.00 Acres

    7 Acres Tidal Creek Land

    Pristine 7-acre land with tidal creek access, no HOA.

    J. Stephens Path, Saint Helena Island, SC 29920
    View details
    Saint Helena Island Waterfront Land
    Contact for pricing

    Saint Helena Island Waterfront Land

    Scenic property with timber and frontage on Village Creek.

    1323 Sea Island Pkwy, Saint Helena Island, SC 29920
    View details

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Beaufort Land Parcel For Sale
    $199,000
    3.40 Acres

    Beaufort Land Parcel For Sale

    3.4 acre building lot near town and airport.

    56 Thomas Atkins Rd, Beaufort, SC 29907
    View details
    Highway Frontage Commercial Development Opportunity
    $1,250,000
    2.50 Acres

    Highway Frontage Commercial Development Opportunity

    Prime commercial land with high visibility and development potential.

    205 Sea Island Pkwy, Beaufort, SC 29907
    View details
    Lady's Island Commercial Site
    Pending
    $499,000
    1.30 Acres

    Lady's Island Commercial Site

    High-traffic commercial land in Lady's Island Village Center.

    Hazel Farm Rd, Ladys Island, SC 29907
    View details
    Lady's Island Commercial Site
    Pending
    $499,000
    1.39 Acres

    Lady's Island Commercial Site

    High-traffic commercial land in Lady's Island Village Center.

    Fry Rd, Ladys Island, SC 29907
    View details

    Saint Helena, SC Commercial Real Estate Investment Opportunities Market Analysis

    Explore 16 commercial real estate for sale in Saint Helena, SC, showcased through 118 active listings on our real estate platform. These investment opportunities span a total of 4,470,563 square feet of properties for sale, with an estimated market value of $9,530,900.

    Sale prices for business properties in Saint Helena, SC start at $149,000, averaging $680,778, and reaching up to $2,299,900 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

    List
    Map

    Browse Commercial real estate for Sale Near Saint Helena, SC

    Popular Searches in Saint Helena, SC

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!