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    Cherokee County, SC Commercial Real Estate for Sale

    185 results
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    Commercial Building with Prime Frontage
    $115,000
    1,951 SF

    Commercial Building with Prime Frontage

    600 Cherokee Ave, Gaffney, SC 29341

    Commercial property with office space, storage, and high-visibility frontage.

    • Prime business location with high visibility (210 feet of frontage).
    • Includes existing rental income from Dora's Alteration (756 sqft, month‑to‑month).
    • Ample parking with paved areas at the front, side, and rear.
    • Versatile office space with four offices, reception area, and a large divisible office.
    • Connected additional building with separate entrance (Dora's Alteration).
    Updated: Dec 29, 2025
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    Gaffney Office Center For Sale
    Contact for pricing
    1,545 SF

    Gaffney Office Center For Sale

    206 Chesnee Hwy, Gaffney, SC 29341

    Brick office center with leasing opportunities in Gaffney, South Carolina.

    • High‑traffic location: Situated on scenic Highway 11 with approximately 10,000 daily traffic count.
    • Convenient access: Located directly off I‑85, Exit 92.
    • Energy‑efficient features: Includes spray foam insulation and new energy‑efficient HVAC systems.
    • Flexible space options: Two adjacent 1540 sqft units available, with the option to combine for double the square footage.
    • Diverse tenant mix: Current tenants include insurance, investment, staffing, retail, dental, medical, and home health businesses.
    Updated: Dec 2, 2025
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    Gaffney Commercial Property For Sale
    $125,000
    1,423 SF

    Gaffney Commercial Property For Sale

    Commercial property in prime location with flexible layout.

    915 N Limestone St, Gaffney, SC 29341
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    Downtown Gaffney Commercial Conversion Opportunity
    $515,000
    7,425 SF

    Downtown Gaffney Commercial Conversion Opportunity

    Prime commercial property in downtown Gaffney with conversion potential.

    423 N Limestone St, Gaffney, SC 29340
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    Downtown Gaffney Historical Building
    $515,000
    7,425 SF

    Downtown Gaffney Historical Building

    Three-story, 7425 SF historical building in downtown Gaffney, SC.

    423 N Limestone St, Gaffney, SC 29340
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    Updated Duplex in Historical District
    $325,000

    Updated Duplex in Historical District

    Fully updated duplex in desirable location, potential for rental income.

    226 College Dr, Gaffney, SC 29340
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    Blacksburg Commercial Land Investment
    $550,000
    23.95 Acres

    Blacksburg Commercial Land Investment

    23.95 Acres, I-85 Frontage, High Visibility

    00 Mill Creek Rd, Blacksburg, SC 29702
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    Hwy 5 Blacksburg Development Land
    Contact for pricing

    Hwy 5 Blacksburg Development Land

    108 Acres, Mixed-Use Potential, SC

    0 Loves Farm Rd, Blacksburg, SC 29702
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    Gaffney Flex Space - $3.5M
    $3,499,000
    16,457 SF

    Gaffney Flex Space - $3.5M

    High-visibility flex space, I-85 access.

    630 Hampshire Dr, Gaffney, SC 29341
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    Cherokee County Industrial Site
    Contact for pricing
    50,000 SF

    Cherokee County Industrial Site

    Prime SC manufacturing land, rail access.

    0 Cherokee St, Blacksburg, SC 29702
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    Gaffney Restaurant - $449,000
    $449,000
    2,522 SF

    Gaffney Restaurant - $449,000

    Turnkey Restaurant, 2522 SF, 1.69 Acres

    1725 Limestone St, Gaffney, SC 29340
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    Gaffney Industrial Flex Building
    $2,200,000
    20,000 SF

    Gaffney Industrial Flex Building

    20,000 SF Flex Warehouse, I-85 Visibility

    244 Shelby Hwy, Gaffney, SC 29340
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    Blacksburg Industrial Land Opportunity
    $150,000

    Blacksburg Industrial Land Opportunity

    Manufacturing Land, I-85 Visibility, Tax Credits

    0 Henson Rd, Blacksburg, SC 29702
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    Gaffney Industrial Warehouse
    Contact for pricing
    113,000 SF

    Gaffney Industrial Warehouse

    113,000 SF Warehouse, Excellent Condition

    1 Commerce Dr, Gaffney, SC 29340
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    Renovated Restaurant Space For Sale
    $449,000
    2,522 SF

    Renovated Restaurant Space For Sale

    Newly renovated restaurant with two hood systems and ample parking.

    1725 N Limestone St, Gaffney, SC 29340
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    Gaffney Industrial Property For Sale
    $2,200,000
    20,000 SF

    Gaffney Industrial Property For Sale

    20,000 SF industrial property in Gaffney, South Carolina.

    244 Shelby Hwy, Gaffney, SC 29340
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    Versatile Industrial Facility with Event Space
    Contact for pricing
    82,976 SF

    Versatile Industrial Facility with Event Space

    82,976 SF industrial facility with adaptable event space.

    811 Hamrick St, Gaffney, SC 29340
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    Gaffney Warehouse with Heavy Power
    $1,300,000
    20,000 SF

    Gaffney Warehouse with Heavy Power

    20,000 SF warehouse featuring dock and drive-in doors.

    373 Huntington Rd, Gaffney, SC 29341
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    Gaffney Industrial Property for Sale
    $975,000
    13,250 SF

    Gaffney Industrial Property for Sale

    Industrial property featuring 13,250 square feet of space in Gaffney.

    298 Willis St, Gaffney, SC 29341
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    Gaffney Warehouse Property For Sale
    $1,080,000
    12,000 SF

    Gaffney Warehouse Property For Sale

    12,000 square foot industrial warehouse property in Gaffney, SC.

    255 Henderson St, Gaffney, SC 29341
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    Gaffney Warehouse For Sale
    $3,499,000
    16,457 SF

    Gaffney Warehouse For Sale

    16,457 square foot warehouse in Gaffney, South Carolina.

    630 Hampshire Dr, Gaffney, SC 29341
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    Explore Off-Market Properties in Cherokee County, SC

    Consider similar Off-Market properties in Cherokee County, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    1305 Floyd Baker Blvd

    1305 Floyd Baker Blvd

    Neighborhood centers • 29,125 SF
    Value Estimation by Request
    1305 Floyd Baker Blvd, Gaffney, SC 29341
    View details
    759 Mill Creek Rd

    759 Mill Creek Rd

    Refrigerated & Cold Storages • 43,200 SF
    Value Estimation by Request
    759 Mill Creek Rd, Blacksburg, SC 29702
    View details
    Seller Financing Available! Restaurant For Sale With Real Est

    Seller Financing Available! Restaurant For Sale With Real Est

    Restaurants • 6,000 SF
    Value Estimation by Request
    Seller Financing Available! Restaurant For Sale With Real Est, Blacksburg, SC 29702
    View details

    Cherokee County, SC Commercial Real Estate Investment Opportunities Market Analysis

    Explore 1225 commercial real estate investment opportunities in Cherokee County, SC with 185 listings featured on our commercial real estate marketplace. The current inventory includes 290,577,266 square feet of properties with an estimated value of $318,431,736.

    Estimated prices for commercial real estate in Cherokee County, SC begin at $35,000, with an average of $429,732 and extend to $16,900,000.

    In Cherokee County, SC, current investment values show:

    • Other commercial real estate positioned at $414,390
    • Land measuring $741,797
    • Commercial land assessed at $763,832
    • Residential land & home lots calculated at $99,253
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