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E Syracuse, NY

E Syracuse, NY Commercial Real Estate for Sale

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Dewitt, NY Salina, NY Manlius, NY Fayetteville, NY Cicero, NY Jamesville, NY Nedrow, NY Clay, NY

28 properties

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East Syracuse Commercially Zoned Land

Updated: Nov 10, 2025

East Syracuse Commercially Zoned Land

L14 Fly Road, East Syracuse, NY 13214

$59,900

17.37 AC lot

17.37 acres of commercially zoned land in the Town of DeWitt, East Syracuse.
Exceptional opportunity for commercial, industrial, or high‑tech development.
Borders the North Branch Ley Creek.
Unparalleled access to Interstates 81, 90, 481, and Route 690, Hancock International Airport, and Class I and II rail systems.
Located in a thriving eastern suburb of Syracuse with a strong economic base.

Commercial Lot in East Syracuse

Updated: Apr 21

Commercial Lot in East Syracuse

Robert Street, East Syracuse, NY 13057

Contact for pricing

0.20 AC lot

Affordable lot in a commercial area
Close proximity to Amazon
Easy access to highways 481 and 690
Water access at the street
Suitable for parking vehicles/equipment or building a storage garage

Industrial Property with Multiple Cranes

Industrial Property with Multiple Cranes

5970 Butternut Dr, East Syracuse, NY 13057

$1,500,000

9,450 sqft

Industrial facility with 5-ton and 2-ton cranes and multiple grade-level doors across three structures.

Turn Any Listing Into an Investment Snapshot Owner equity, real caprate, demand score for every listing. Go To Analytics Center

Class A Office Building

Class A Office Building

6611 Manlius Center Road, East Syracuse, NY 13057

$13,000,000

45,450 sqft 2.30 AC lot

Net leased office building with bank branch and lower level.

Built Commissary Kitchen Opportunity

Built Commissary Kitchen Opportunity

6491 Collamer Rd, East Syracuse, NY 13057

$299,000

1,572 sqft

Fully built commissary kitchen with flexible layout and street frontage suitable for conversion to office or retail.

Leased Warehouse and Office Investment

Leased Warehouse and Office Investment

7406 Taft Park Drive, East Syracuse, NY

$2,500,000

24,566 sqft

24,566 SF leased building on 2.05 acres in East Syracuse.

Fully Leased Industrial Property

Fully Leased Industrial Property

4223 James St, East Syracuse, NY 13057

$900,000

6,250 sqft 0.71 AC lot

Income-producing industrial property in East Syracuse with highway access.

Stand Alone Industrial Building

Stand Alone Industrial Building

5081 Whirlybird Lane, East Syracuse, NY 13057

$2,400,000

17,098 sqft

Industrial building featuring loading docks and drive-in door.

Class A Office Building

Class A Office Building

6706 Collamer Road, East Syracuse, NY

$6,100,000

22,779 sqft

Class A office building with training facility in East Syracuse.

Available Warehouse Near Major Highways

Available Warehouse Near Major Highways

6800 Newbrook Ave, E Syracuse, NY

$950,000

6,264 sqft 0.41 AC lot

6,264± SF warehouse space with convenient highway access.

Manufacturing Warehouse with Office Space

Manufacturing Warehouse with Office Space

6250 E Molloy Rd, East Syracuse, NY

$2,920,000

30,000 sqft 2.30 AC lot

30,000 SF manufacturing/warehouse with 8,000 SF office space.

Established Medical Transportation Business Opportunity

Established Medical Transportation Business Opportunity

6500 New Venture Gear Dr, East Syracuse, NY 13057

Contact for pricing

8,000 sqft

Thriving medical transportation business with contracts and growth potential.

Shovel Ready Land Available

Shovel Ready Land Available

5855 Widewaters Parkway, East Syracuse, NY

Contact for pricing

5 sqft

5.28 acres of land with utilities and interstate access.

Erie Boulevard Investment Opportunity

Erie Boulevard Investment Opportunity

3125 Erie Blvd E, East Syracuse, NY 13057

$1,500,000

6,000 sqft

6,000 SF property with long-term FedEx lease.

Class A Office Building

Class A Office Building

34 Aspen Park Blvd, East Syracuse, NY

Contact for pricing

25,000 sqft 6.84 AC lot

25,000 SF Class A office building in growing area.

Vacant Land in Retail Hub

Vacant Land in Retail Hub

5814 Bridge St, East Syracuse, NY

$3,500,000

5.60 AC lot

5.6 AC vacant land suitable for retail or mixed-use development.

Industrial Land Near Highway

Industrial Land Near Highway

7021 Fly Rd, East Syracuse, NY 13057

$318,000

Industrial land for sale with highway access in Dewitt.

9.73 Acre Site For Sale

9.73 Acre Site For Sale

5000 Brittonfield Pkwy, East Syracuse, NY

$3,000,000

9.73 AC lot

9.73 acre site in Brittonfield Office Park.

I-90E Frontage Land For Sale

I-90E Frontage Land For Sale

0 Kinne St, East Syracuse, NY

$1,500,000

7.07 AC lot

Land with excellent visibility and access to major transportation routes.

Development Opportunity in Dewitt, NY

Development Opportunity in Dewitt, NY

Burnet Ave, East Syracuse, NY

Contact for pricing

0.81 AC lot

Prime industrial-zoned land for development in Dewitt, NY.

Restaurant and Banquet Facility

Restaurant and Banquet Facility

6400 Yorktown Cir, East Syracuse, NY

$3,400,000

2.43 AC lot

10,600 SF restaurant/banquet facility on 2.43 acres.

Former Restaurant Site in Syracuse

Former Restaurant Site in Syracuse

6596 Old Collamer Rd, East Syracuse, NY 13057

$295,000

2,373 sqft

East Syracuse location ideal for restaurant, office, or retail.

Industrial Land in East Syracuse

Industrial Land in East Syracuse

0000 Newbrook Ave, East Syracuse, NY 13057

$279,000

7.68 AC lot

7.68 acres of industrial-zoned land in a commercial district.

Prime Industrial Land Near I-481

Prime Industrial Land Near I-481

6834 Kirkville Road, East Syracuse, NY

Contact for pricing

32 acres of industrial land near I-481 interchange.

E Syracuse, NY Commercial Real Estate Market Trends and Statistics

Explore 28 commercial real estate for sale in E Syracuse, NY, showcased through 28 active listings on our real estate platform. These investment opportunities span a total of 162,352 square feet of properties for sale, with an estimated market value of $30,864,000.

Sale prices for business properties in E Syracuse, NY start at $295,000, averaging $3,086,400, and reaching up to $13,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Demographics Overview

Population 23K

Population Growth (5Y) +2.7%

Median Household Income $83,654

College Educated 63.4%

Listings Trend

New vs delisted commercial listings in Onondaga County

New Delisted

Total CRE Inventory on Market (SF)

Average Property Price per SF

For-sale pricing trends across core commercial property types in Onondaga County

Office

Residential Income

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