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    E Syracuse, NY Commercial Real Estate for Sale

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    Dewitt, NY Accord, NY Fayetteville, NY
    21 results
    Modern Class A Office Building
    $4,500,000
    40,625 SF

    Modern Class A Office Building

    5062 Brittonfield Pkwy, East Syracuse, NY

    40,625 SF office building ideal for medical or conventional use.

    • Exceptional visibility and exposure at the corner of Collamer Rd (NYS Route 298) and Brittonfield Pkwy
    • 40,625 SF modern, single‑story, professional Class A Office building on 4.81 AC
    • Abundant parking: 281 spaces (7.0/1,000 SF) well above market ratios
    • Ideal for medical or conventional office use
    • Efficient, versatile floor plan can easily accommodate single or multi‑tenant layouts
    Updated: Sep 26, 2025
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    Commercial Lot in East Syracuse
    Contact for pricing
    0.20 Acres

    Commercial Lot in East Syracuse

    Robert Street, East Syracuse, NY 13057

    Affordable lot for parking or storage in commercial area.

    • Affordable lot in a commercial area
    • Close proximity to Amazon
    • Easy access to highways 481 and 690
    • Water access at the street
    • Suitable for parking vehicles/equipment or building a storage garage
    Updated: Apr 21
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    Available Warehouse Near Major Highways
    $950,000
    6,264 SF

    Available Warehouse Near Major Highways

    6,264± SF warehouse space with convenient highway access.

    6800 Newbrook Ave, E Syracuse, NY
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    Class A Office Building
    $13,000,000
    45,450 SF

    Class A Office Building

    Net leased office building with bank branch and lower level.

    6611 Manlius Center Road, East Syracuse, NY 13057
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    Established Medical Transportation Business Opportunity
    Contact for pricing
    8,000 SF

    Established Medical Transportation Business Opportunity

    Thriving medical transportation business with contracts and growth potential.

    6500 New Venture Gear Dr, East Syracuse, NY 13057
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    Manufacturing Warehouse with Office Space
    $2,920,000
    30,000 SF

    Manufacturing Warehouse with Office Space

    30,000 SF manufacturing/warehouse with 8,000 SF office space.

    6250 E Molloy Rd, East Syracuse, NY
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    Stand Alone Industrial Building
    $2,400,000
    17,098 SF

    Stand Alone Industrial Building

    Industrial building featuring loading docks and drive-in door.

    5081 Whirlybird Lane, East Syracuse, NY 13057
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    Fully Leased Industrial Property
    $900,000
    6,250 SF

    Fully Leased Industrial Property

    Income-producing industrial property in East Syracuse with highway access.

    4223 James St, East Syracuse, NY 13057
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    East Syracuse Commercially Zoned Land
    $59,900
    17.37 Acres

    East Syracuse Commercially Zoned Land

    17.37 acres of commercially zoned land for sale.

    L14 Fly Road, East Syracuse, NY 13214
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    Mixed-Use Investment Opportunity
    $150,000
    3,300 SF

    Mixed-Use Investment Opportunity

    Retail, warehouse, and apartments. Redevelopment potential.

    7545 Kirkville Rd, East Syracuse, NY
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    Industrial Land Near Highway
    $318,000

    Industrial Land Near Highway

    Industrial land for sale with highway access in Dewitt.

    7021 Fly Rd, East Syracuse, NY 13057
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    Class A Office Building
    Contact for pricing
    25,000 SF

    Class A Office Building

    25,000 SF Class A office building in growing area.

    34 Aspen Park Blvd, East Syracuse, NY
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    Vacant Land in Retail Hub
    $3,500,000
    5.60 Acres

    Vacant Land in Retail Hub

    5.6 AC vacant land suitable for retail or mixed-use development.

    5814 Bridge St, East Syracuse, NY
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    I-90E Frontage Land For Sale
    $1,500,000
    7.07 Acres

    I-90E Frontage Land For Sale

    Land with excellent visibility and access to major transportation routes.

    0 Kinne St, East Syracuse, NY
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    Restaurant and Banquet Facility
    $3,400,000
    2.43 Acres

    Restaurant and Banquet Facility

    10,600 SF restaurant/banquet facility on 2.43 acres.

    6400 Yorktown Cir, East Syracuse, NY
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    9.73 Acre Site For Sale
    $3,000,000
    9.73 Acres

    9.73 Acre Site For Sale

    9.73 acre site in Brittonfield Office Park.

    5000 Brittonfield Pkwy, East Syracuse, NY
    View details
    Erie Boulevard Investment Opportunity
    $1,500,000
    6,000 SF

    Erie Boulevard Investment Opportunity

    6,000 SF property with long-term FedEx lease.

    3125 Erie Blvd E, East Syracuse, NY 13057
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    Development Opportunity in Dewitt, NY
    Contact for pricing
    0.81 Acres

    Development Opportunity in Dewitt, NY

    Prime industrial-zoned land for development in Dewitt, NY.

    Burnet Ave, East Syracuse, NY
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    Prime Industrial Land Near I-481
    Contact for pricing
    32.03 Acres

    Prime Industrial Land Near I-481

    32 acres of industrial land near I-481 in DeWitt.

    Kirkville Rd, East Syracuse, NY
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    Former Restaurant Site in Syracuse
    $295,000
    2,373 SF

    Former Restaurant Site in Syracuse

    East Syracuse location ideal for restaurant, office, or retail.

    6596 Old Collamer Rd, East Syracuse, NY 13057
    View details
    9.73 Acre Commercial Land Site
    $3,000,000
    9.73 Acres

    9.73 Acre Commercial Land Site

    9.73 acre commercial land for sale in East Syracuse.

    5555 Brittonfield Pkwy, East Syracuse, NY 13057
    View details
    Based on your search, we've compiled Potential Opportunities for your consideration. Besides 21 Active Listings in E Syracuse, NY

    E Syracuse, NY Commercial Real Estate Investment Opportunities Market Analysis

    Explore 21 commercial real estate for sale in E Syracuse, NY, showcased through 21 active listings on our real estate platform. These investment opportunities span a total of 157,360 square feet of properties for sale, with an estimated market value of $26,615,000.

    Sale prices for business properties in E Syracuse, NY start at $150,000, averaging $2,957,222, and reaching up to $13,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Demographics Overview

    Population 23K
    Population Growth (5Y) +2.7%
    Median Household Income $83,654
    College Educated 63.4%

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    Most Searched ZIP Codes in E Syracuse, NY

    • 13057
    • 13214

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