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E Syracuse, NY Commercial Real Estate for Sale

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20 results
East Syracuse Commercially Zoned Land
$59,900
17.37 Acres

East Syracuse Commercially Zoned Land

L14 Fly Road, East Syracuse, NY 13214

17.37 acres of commercially zoned land for sale.

  • 17.37 acres of commercially zoned land in the Town of DeWitt, East Syracuse.
  • Exceptional opportunity for commercial, industrial, or high‑tech development.
  • Borders the North Branch Ley Creek.
  • Unparalleled access to Interstates 81, 90, 481, and Route 690, Hancock International Airport, and Class I and II rail systems.
  • Located in a thriving eastern suburb of Syracuse with a strong economic base.
Updated: Nov 10, 2025
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Modern Class A Office Building
$4,500,000
40,625 SF

Modern Class A Office Building

5062 Brittonfield Pkwy, East Syracuse, NY

40,625 SF office building ideal for medical or conventional use.

  • Exceptional visibility and exposure at the corner of Collamer Rd (NYS Route 298) and Brittonfield Pkwy
  • 40,625 SF modern, single‑story, professional Class A Office building on 4.81 AC
  • Abundant parking: 281 spaces (7.0/1,000 SF) well above market ratios
  • Ideal for medical or conventional office use
  • Efficient, versatile floor plan can easily accommodate single or multi‑tenant layouts
Updated: Sep 26, 2025
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Available Warehouse Near Major Highways
$950,000
6,264 SF

Available Warehouse Near Major Highways

6,264± SF warehouse space with convenient highway access.

6800 Newbrook Ave, E Syracuse, NY
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Class A Office Building
$13,000,000
45,450 SF

Class A Office Building

Net leased office building with bank branch and lower level.

6611 Manlius Center Road, East Syracuse, NY 13057
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Established Medical Transportation Business Opportunity
Contact for pricing
8,000 SF

Established Medical Transportation Business Opportunity

Thriving medical transportation business with contracts and growth potential.

6500 New Venture Gear Dr, East Syracuse, NY 13057
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Stand Alone Industrial Building
$2,400,000
17,098 SF

Stand Alone Industrial Building

Industrial building featuring loading docks and drive-in door.

5081 Whirlybird Lane, East Syracuse, NY 13057
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Fully Leased Industrial Property
$900,000
6,250 SF

Fully Leased Industrial Property

Income-producing industrial property in East Syracuse with highway access.

4223 James St, East Syracuse, NY 13057
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Manufacturing Warehouse with Office Space
$2,920,000
30,000 SF

Manufacturing Warehouse with Office Space

30,000 SF manufacturing/warehouse with 8,000 SF office space.

6250 E Molloy Rd, East Syracuse, NY
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Class A Office Building
Contact for pricing
25,000 SF

Class A Office Building

25,000 SF Class A office building in growing area.

34 Aspen Park Blvd, East Syracuse, NY
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Mixed-Use Investment Opportunity
$150,000
3,300 SF

Mixed-Use Investment Opportunity

Retail, warehouse, and apartments. Redevelopment potential.

7545 Kirkville Rd, East Syracuse, NY
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Vacant Land in Retail Hub
$3,500,000
5.60 Acres

Vacant Land in Retail Hub

5.6 AC vacant land suitable for retail or mixed-use development.

5814 Bridge St, East Syracuse, NY
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Industrial Land Near Highway
$318,000

Industrial Land Near Highway

Industrial land for sale with highway access in Dewitt.

7021 Fly Rd, East Syracuse, NY 13057
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Development Opportunity in Dewitt, NY
Contact for pricing
0.81 Acres

Development Opportunity in Dewitt, NY

Prime industrial-zoned land for development in Dewitt, NY.

Burnet Ave, East Syracuse, NY
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I-90E Frontage Land For Sale
$1,500,000
7.07 Acres

I-90E Frontage Land For Sale

Land with excellent visibility and access to major transportation routes.

0 Kinne St, East Syracuse, NY
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Restaurant and Banquet Facility
$3,400,000
2.43 Acres

Restaurant and Banquet Facility

10,600 SF restaurant/banquet facility on 2.43 acres.

6400 Yorktown Cir, East Syracuse, NY
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Erie Boulevard Investment Opportunity
$1,500,000
6,000 SF

Erie Boulevard Investment Opportunity

6,000 SF property with long-term FedEx lease.

3125 Erie Blvd E, East Syracuse, NY 13057
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Former Restaurant Site in Syracuse
$295,000
2,373 SF

Former Restaurant Site in Syracuse

East Syracuse location ideal for restaurant, office, or retail.

6596 Old Collamer Rd, East Syracuse, NY 13057
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Stand Alone Industrial Building
$2,400,000
17,098 SF

Stand Alone Industrial Building

Industrial building for sale with loading docks and drive-in door.

5081 Whirlybird Lane, East Syracuse, NY 13057
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Shovel Ready Land Available
$3,000,000

Shovel Ready Land Available

5.28 acres of land with utilities and highway access.

5855 Widewaters Pkwy, East Syracuse, NY 13057
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9.73 Acre Commercial Land Site
$3,000,000

9.73 Acre Commercial Land Site

9.73 acre commercial land for sale in East Syracuse.

5555 Brittonfield Pkwy, East Syracuse, NY 13057
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Based on your search, we've compiled Potential Opportunities for your consideration. Besides 20 Active Listings in E Syracuse, NY

E Syracuse, NY Commercial Real Estate Investment Opportunities Market Analysis

Explore 20 commercial real estate for sale in E Syracuse, NY, showcased through 20 active listings on our real estate platform. These investment opportunities span a total of 0 square feet of properties for sale, with an estimated market value of $950,000.

Sale prices for business properties in E Syracuse, NY start at $950,000, averaging $950,000, and reaching up to $950,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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