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    South Portland, ME Commercial Real Estate for Sale

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    Mixed-Use Property in South Portland
    $560,000
    0.23 Acres

    Mixed-Use Property in South Portland

    854 Broadway, South Portland, ME 04106

    Mixed-use property with office spaces and apartment in South Portland.

    • Mixed‑use property in a highly visible location on a popular commuter street.
    • Immaculate 1‑bedroom apartment on the 3rd floor featuring 2 egresses, cherry cabinets, and granite counters.
    • Two first‑floor office spaces with separate entries and beautiful hardwood floors.
    • Four individual offices on the second floor.
    • Detached 1‑car garage leased year‑round.
    Updated: Oct 30, 2025
    View details
    South Portland Medical Office Building
    Contact for pricing
    17,071 SF

    South Portland Medical Office Building

    244 Western Ave, South Portland, ME 04106

    17,071 SF Medical Office, Ample Parking

    • 17,071 SF medical office building on a 2.61‑acre lot in South Portland, ME.
    • Subdividable building with ample on‑site parking (approx. 92 spaces).
    • High visibility and excellent signage opportunities.
    • Features 11 exam rooms, 3 treatment rooms, and 2 operating rooms.
    • Available for sale, also for lease in Summer 2025.
    Updated: Dec 11, 2024
    View details
    South Portland Medical Investment Opportunity
    $4,327,286
    7,424 SF

    South Portland Medical Investment Opportunity

    Long-term NNN investment with a strong healthcare tenant.

    254 Western Ave, South Portland, ME 04106
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    Commercial Zoned Property For Sale
    Contact for pricing
    2,100 SF

    Commercial Zoned Property For Sale

    Commercial zoned property ideal for contractor, roofer, or storage.

    179 Lincoln St, South Portland, ME 04106
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    Retail Building Near Maine Mall
    $4,650,000
    20,700 SF

    Retail Building Near Maine Mall

    20,700 SF retail building on 2 acres for sale.

    130 Western Ave, South Portland, ME 04106
    View details
    Based on your search, we've compiled 777 Potential Opportunities for your consideration. Besides 5 Active listings in South Portland, ME, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 767 Off-Market properties to explore as potential leads, plus 1 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Well-Maintained Two-Unit Multifamily Property
    $525,000
    1,234 SF

    Well-Maintained Two-Unit Multifamily Property

    Two-unit property in Portland with modern updates and convenient location.

    9 C St, Portland, ME 04102
    View details
    Portland Warehouse/Retail Building For Sale
    $995,000
    6,204 SF

    Portland Warehouse/Retail Building For Sale

    6,204± SF warehouse/retail building with on-site parking.

    1004 Congress St, Portland, ME 04102
    View details
    Prime Scarborough Industrial Land
    Contact for pricing
    15.00 Acres

    Prime Scarborough Industrial Land

    Up to 40 acres, ideal for warehousing.

    107 Mussey Rd, Scarborough, ME 04074
    View details
    Undeveloped Land Parcel For Sale
    $3,000,000

    Undeveloped Land Parcel For Sale

    Undeveloped land with frontage on Mussey Road and I-295.

    114 Mussey Rd, Scarborough, ME 04074
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    South Portland Commercial Land Opportunity
    Contact for pricing
    25,000 SF

    South Portland Commercial Land Opportunity

    4.14 acre commercial land parcel in South Portland, Maine.

    305 Cummings Rd, South Portland, ME 04106
    View details

    Explore Off-Market Properties in South Portland, ME

    Consider similar Off-Market properties in South Portland, ME. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    600 Southborough Dr

    600 Southborough Dr

    Office Properties & Spaces • 32,803 SF
    Value Estimation by Request
    600 Southborough Dr, South Portland, ME 04106
    View details
    25 Long Creek Dr

    25 Long Creek Dr

    Medical offices • 4,532 SF
    Value Estimation by Request
    25 Long Creek Dr, South Portland, ME 04106
    View details
    566 Main St

    566 Main St

    Individual retail properties • 5,120 SF
    Value Estimation by Request
    566 Main St, South Portland, ME 04106
    View details
    72 Ocean St

    72 Ocean St

    Individual retail properties • 1,620 SF
    Value Estimation by Request
    72 Ocean St, South Portland, ME 04106
    View details
    95-97 Darling Ave

    95-97 Darling Ave

    Restaurants • 42,000 SF
    Value Estimation by Request
    95-97 Darling Ave, South Portland, ME 04106
    View details
    25 Long Creek Dr

    25 Long Creek Dr

    Medical offices • 16,150 SF
    Value Estimation by Request
    25 Long Creek Dr, South Portland, ME 04106
    View details
    280 Lincoln St

    280 Lincoln St

    Multifamily properties • 9,854 SF
    Value Estimation by Request
    280 Lincoln St, South Portland, ME 04106
    View details
    78 Atlantic Pl

    78 Atlantic Pl

    Office Properties & Spaces • 23,750 SF
    Value Estimation by Request
    78 Atlantic Pl, South Portland, ME 04106
    View details
    175 Frnt St

    175 Frnt St

    INDUSTRIAL (GENERAL) • 10,016 SF
    Value Estimation by Request
    175 Frnt St, South Portland, ME 04106-1509
    View details
    1 Wallace Ave

    1 Wallace Ave

    WAREHOUSE, STORAGE • 4.66 Acres
    Value Estimation
    $285,000
    1 Wallace Ave, South Portland, ME 04106-6176
    View details
    312 Gannett Dr

    312 Gannett Dr

    CONDOMINIUMS (INDUSTRIAL) • 5,286 SF
    Value Estimation by Request
    312 Gannett Dr, South Portland, ME 04106-6912
    View details
    10 Billy Vachon St

    10 Billy Vachon St

    WAREHOUSE, STORAGE • 5.87 Acres
    Value Estimation by Request
    10 Billy Vachon St, South Portland, ME 04106
    View details
    155 Rumery St

    155 Rumery St

    INDUSTRIAL (GENERAL) • 5.33 Acres
    Value Estimation by Request
    155 Rumery St, South Portland, ME 04106-6231
    View details
    23 Central Ave

    23 Central Ave

    WAREHOUSE, STORAGE • 4.30 Acres
    Value Estimation by Request
    23 Central Ave, South Portland, ME 04106
    View details
    55 Lincoln St

    55 Lincoln St

    WAREHOUSE, STORAGE • 6.07 Acres
    Value Estimation by Request
    55 Lincoln St, South Portland, ME 04106-2612
    View details
    22 Central Ave

    22 Central Ave

    INDUSTRIAL (GENERAL) • 7,509 SF
    Value Estimation by Request
    22 Central Ave, South Portland, ME 04106
    View details
    1 Hemco Rd

    1 Hemco Rd

    WAREHOUSE, STORAGE • 13,691 SF
    Value Estimation by Request
    1 Hemco Rd, South Portland, ME 04106-6217
    View details
    159 Cash St

    159 Cash St

    INDUSTRIAL (GENERAL) • 3,780 SF
    Value Estimation by Request
    159 Cash St, South Portland, ME 04106-6258
    View details
    1st Wallace Ave

    1st Wallace Ave

    WAREHOUSE, STORAGE • 4,280 SF
    Value Estimation by Request
    1st Wallace Ave, South Portland, ME 04106-6143
    View details

    South Portland, ME Commercial Real Estate Investment Opportunities Market Analysis

    Explore 682 commercial real estate investment opportunities in South Portland, ME on our commercial real estate marketplace. The current inventory includes 11,627,040 square feet of properties with an estimated value of $197,600,000.

    Estimated prices for commercial real estate in South Portland, ME begin at $65,000, with an average of $613,664 and extend to $13,400,000.

    In South Portland, ME, current investment values show:

    • Retail properties positioned at $557,517
    • Office Properties & Spaces measuring $448,037
    • Other retail properties assessed at $401,554
    • Office buildings calculated at $486,724
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    Browse Commercial real estate for Sale Near South Portland, ME

    Popular Searches in South Portland, ME

    Most Searched ZIP Codes in South Portland, ME

    • 04106

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