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Orleans, MA Commercial Real Estate for Sale

21 results
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Orleans Office Building For Sale
$3,900,000
14,341 SF

Orleans Office Building For Sale

8 Cardinal Lane, Orleans, MA 02653

14,340 SF office building on 2.6+ acres in Orleans.

  • Prime location in the heart of Orleans, near Main Street retail, Route 6A, and US Route 6, offering superior accessibility.
  • Substantial 14,340 sq ft office building on a large 2.6+ acre private lot with exceptional parking facilities.
  • Excellent condition of the building, featuring a warm reception area and four wings of offices and meeting space.
  • Versatile property with potential for professional office, mixed‑use, residential, or investment opportunities.
  • Convenient access to Cape Cod Rail Trail / Bike Trail.
Updated: Dec 30, 2025
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Turnkey Commercial Building in Orleans
$950,000
1,548 SF

Turnkey Commercial Building in Orleans

29 West Road, Orleans, MA 02653

Renovated mixed-use building in top location with highway access.

  • Fully renovated, turn‑key commercial building in a top location.
  • Impressive conference space with gleaming wood floors and fine finishes.
  • Convenient location adjacent to Shaw's Plaza, near restaurants, shops, and bike path with easy highway access.
  • Functional layout with reception office, private offices, 2 accessible bathrooms, and kitchen/break room.
  • New sewer connection, freshly paved parking lot, retaining walls, and coastal landscaping.
Updated: Oct 20, 2025
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Orleans Office Condo For Sale
$1,399,000
3,595 SF

Orleans Office Condo For Sale

3,595 SF commercial condo in the heart of Orleans.

32 Main Street unit: B, Orleans, MA 02653
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Orleans Mixed-Use Investment Opportunity
$2,150,000
3,843 SF

Orleans Mixed-Use Investment Opportunity

Three parcels in Orleans Village Center District with mixed-use potential.

88 Route 6A, Orleans, MA 02653
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Orleans Commercial/Industrial Flex Space
$1,800,000
1,920 SF

Orleans Commercial/Industrial Flex Space

Versatile commercial property suitable for storage, manufacturing, or service operations.

9 Rayber Road, Orleans, MA 02653
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Iconic Cape Cod Lantern Business
$695,000
3,670 SF

Iconic Cape Cod Lantern Business

Historic lantern business for sale in Orleans Village.

48 Main Street, Orleans, MA 02653
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Historic Cape Cod Lantern Business
$695,000
3,670 SF

Historic Cape Cod Lantern Business

Iconic lantern business for sale in Orleans Village.

48 Main Street, Orleans, MA 2653
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Turnkey Restaurant with Patio Seating
$679,000
1,693 SF

Turnkey Restaurant with Patio Seating

East Orleans restaurant with seating, patio, and liquor license.

222 Main St, Orleans, MA 2653
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Mixed-Use Property in Orleans, MA
$3,975,000
15,100 SF

Mixed-Use Property in Orleans, MA

Landmark mixed-use property with residential and commercial spaces in Orleans.

80-82 Massachusetts 6A, Orleans, MA 02653
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Orleans Village Center Commercial Property
$1,300,000
4,000 SF

Orleans Village Center Commercial Property

Commercial property in excellent condition with expansion potential.

12 Main St, Orleans, MA 2653
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Orleans Office Building For Sale
$3,900,000
14,341 SF

Orleans Office Building For Sale

14,340 SF office building in the heart of Orleans.

8 Cardinal, Orleans, MA 2653
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Commercial Condo on Main Street
$1,399,000
3,595 SF

Commercial Condo on Main Street

3,595 SF commercial condo in central location.

32 Main Street, Orleans, MA 2653
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Orleans Office Space on Main
Contact for pricing
500 SF

Orleans Office Space on Main

Second-floor office space in the heart of Orleans, MA.

26 Main Street, Orleans, MA 2653
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Orleans Commercial/Industrial Flex Space
$1,800,000
1,920 SF

Orleans Commercial/Industrial Flex Space

Exceptionally maintained commercial property suitable for storage, manufacturing, or services.

9 Rayber, Orleans, MA 2653
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Orleans Office Space on Main
Contact for pricing
300 SF

Orleans Office Space on Main

Second-floor office space in downtown Orleans, near Cape Cod Rail Trail.

26 Main Street, Orleans, MA 2653
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Iconic Orleans Property with Potential
$1,900,000
4,887 SF

Iconic Orleans Property with Potential

East Orleans property with high visibility and ample parking.

212 Main Street, Orleans, MA 02653
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Iconic East Orleans Mixed-Use Property
$1,900,000
1.79 Acres

Iconic East Orleans Mixed-Use Property

Prime location with high visibility and ample parking.

212 Main Street, Orleans, MA 2653
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Orleans Mixed-Use Investment Opportunity
$2,150,000
3,843 SF

Orleans Mixed-Use Investment Opportunity

Three parcels with residential and commercial units in central Orleans.

88 Route 6a, Orleans, MA 2653
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Adaptable Commercial Kitchen For Sale
Contact for pricing
2,241 SF

Adaptable Commercial Kitchen For Sale

Commercial kitchen with versatile space suitable for various businesses.

12 Commerce, Orleans, MA 2653
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Orleans Waterfront Lot For Sale
$999,990
0.76 Acres

Orleans Waterfront Lot For Sale

Saltwater front lot with access to Little Pleasant Bay.

7 Lockwood Lane, Orleans, MA 02653
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East Orleans Commercial Space
$1,499,000

East Orleans Commercial Space

Renovated commercial space in village center with development potential.

204 Main Street, Orleans, MA 2653
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Based on your search, we've compiled Potential Opportunities for your consideration. Besides 21 Active Listings in Orleans, MA, we suggest to view alternatives - similar 557 Off-Market properties to explore as potential leads.

Explore Off-Market Properties in Orleans, MA

Consider similar Off-Market properties in Orleans, MA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

18 Old Colony Way

18 Old Colony Way

RESTAURANT • 7,617 SF
Value Estimation
$1,170,000
18 Old Colony Way, Orleans, MA 02653-3214
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44 Orleans Rd

44 Orleans Rd

OFFICE/RESIDENTIAL (MIXED USE) • 3,364 SF
Value Estimation by Request
44 Orleans Rd, Orleans, MA 02653-2423
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31 Main St

31 Main St

RETAIL STORES (PERSONAL SERVICES) • 1,272 SF
Value Estimation
$780,000
31 Main St, Orleans, MA 02653-2414
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Orleans, MA Commercial Real Estate Investment Opportunities Market Analysis

Explore 578 commercial real estate for sale in Orleans, MA, showcased through 21 active listings on our real estate platform. These investment opportunities span a total of 446,926 square feet of properties for sale, with an estimated market value of $18,784,990.

Sale prices for business properties in Orleans, MA start at $695,000, averaging $1,878,499, and reaching up to $3,975,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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