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Hopkinton, MA Commercial Real Estate for Sale

7 results
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Modern Office Building Near Downtown
Contact for pricing
46,857 SF

Modern Office Building Near Downtown

34 Hayden Rowe Street, Hopkinton, MA 1748

Modern office spaces with first-class finishes and convenient location.

  • Exceptional location steps from downtown Hopkinton's Main Street retail corridor with dining, shops, and services.
  • Easy access to Boston and Worcester via Southborough and Ashland commuter rail stations (less than 4 miles).
  • Convenient highway access to I‑495 and I‑90 (Mass Pike).
  • Modern three‑story building with first‑class finishes throughout.
  • Ample windows and wrap‑around natural light creating move‑in ready office space.
Updated: Nov 21, 2025
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Hopkinton Flex Space Opportunity
Contact for pricing
66,024 SF

Hopkinton Flex Space Opportunity

45 South Street, Hopkinton, MA 1748

Flex space available near I-495 and Mass Pike.

  • Convenient highway access: Located directly off I‑495 and near the I‑90 Mass Pike junction, ideal for commuters.
  • Flexible space options: Offers a range of sizes from 4,538 to 34,150 SF to suit various business needs.
  • Established business location: Join successful biotech, technology, medical device, and R&D companies.
  • Proximity to a highly educated workforce: Located in Hopkinton, known for its skilled labor pool.
  • Close to major corporations: Near world‑class companies like EMC Corporation, Caliper Life Sciences, and Liberty Mutual.
Updated: Nov 21, 2025
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Hopkinton Corner Lot Opportunity
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Hopkinton Corner Lot Opportunity

2.32 acre corner lot near Route 495.

290 West Main Street, Hopkinton, MA 1748
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Downtown Hopkinton Mixed-Use Development
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75,300 SF

Downtown Hopkinton Mixed-Use Development

New mixed-use development with retail and residential units.

52 Main Street, Hopkinton, MA 1748
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Hopkinton Warehouse with Expansion Plans
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115,970 SF

Hopkinton Warehouse with Expansion Plans

115,970 SF warehouse with expansion potential and heavy power.

71 Frankland Rd, Hopkinton, MA
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High-Visibility Corner Lot
Contact for pricing
2.32 Acres

High-Visibility Corner Lot

Agricultural zoned land with high traffic and easy access.

52 School St, Hopkinton, MA
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Prime Land Site on Route 135
Contact for pricing
0.75 Acres

Prime Land Site on Route 135

Desirable .75 acre land site in affluent Hopkinton, MA.

83 E Main St, Hopkinton, MA
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Based on your search, we've compiled 241 Potential Opportunities for your consideration. Besides 7 Active listings in Hopkinton, MA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 230 Off-Market properties to explore as potential leads

Explore Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Route 9 Industrial Building
Contact for pricing

Route 9 Industrial Building

15,500 SF light industrial building on 3.81 acres.

251 Turnpike Road, Southborough, MA 1772
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Downtown Retail Storefront with Parking
$299,000
1,660 SF

Downtown Retail Storefront with Parking

Retail storefront with parking and easy loading access.

193 Main St, Ashland, MA 1721
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Ashland Flex Building For Sale
$2,345,000
8,200 SF

Ashland Flex Building For Sale

8,200 SF flex building with fenced yard in Ashland.

190 Pleasant St, Ashland, MA
View details
Route 9 Commercial Land Parcels
$2,150,000
1.84 Acres

Route 9 Commercial Land Parcels

Two parcels on Route 9 approved for 40,000 SF building.

241 Boston - Worcester Tpke, Southborough, MA
View details

Explore Off-Market Properties in Hopkinton, MA

Consider similar Off-Market properties in Hopkinton, MA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

1 Ash St

1 Ash St

OFFICE BUILDING • 8,856 SF
Value Estimation by Request
1 Ash St, Hopkinton, MA 01748-1886
View details
81 Main St

81 Main St

OFFICE/RESIDENTIAL (MIXED USE) • 2,687 SF
Value Estimation
$590,000
81 Main St, Hopkinton, MA 01748-3121
View details
73 Main St

73 Main St

SHOW ROOM, WAREHOUSE • 2,228 SF
Value Estimation
$540,000
73 Main St, Hopkinton, MA 01748-1619
View details
231 Hayden Rowe St

231 Hayden Rowe St

MIXED USE (COMMERCIAL/INDUSTRIAL) • 12.60 Acres
Value Estimation by Request
231 Hayden Rowe St, Hopkinton, MA 01748-2803
View details
75 Ss St

75 Ss St

MANUFACTURING (LIGHT) • 33,040 SF
Value Estimation by Request
75 Ss St, Hopkinton, MA 01748-2204
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91 Grv St

91 Grv St

SERVICE STATION (FULL SERVICE) • 2,644 SF
Value Estimation
$755,000
91 Grv St, Hopkinton, MA 01748-1732
View details
66 Main St

66 Main St

FINANCIAL BUILDING • 1,754 SF
Value Estimation
$700,000
66 Main St, Hopkinton, MA 01748-1124
View details
11 Grv St

11 Grv St

OFFICE BUILDING • 3,043 SF
Value Estimation
$1,950,000
11 Grv St, Hopkinton, MA 01748-2595
View details
71 Main St

71 Main St

RETAIL STORES (PERSONAL SERVICES) • 1,830 SF
Value Estimation
$610,000
71 Main St, Hopkinton, MA 01748-1619
View details
42 Ss St

42 Ss St

INDUSTRIAL (GENERAL) • 129,520 SF
Value Estimation
$4,150,000
42 Ss St, Hopkinton, MA 01748-2201
View details
48-52 Main St

48-52 Main St

RETAIL STORES (PERSONAL SERVICES) • 14,693 SF
Value Estimation
$3,600,000
48-52 Main St, Hopkinton, MA 01748
View details
117 Ss St

117 Ss St

R&D FACILITY, LABS, PHARMA • 59,886 SF
Value Estimation
$4,150,000
117 Ss St, Hopkinton, MA 01748-2206
View details
159 Ash St

159 Ash St

SHOW ROOM, WAREHOUSE • 6,840 SF
Value Estimation
$740,000
159 Ash St, Hopkinton, MA 01748-1903
View details
70 Main St

70 Main St

OFFICE/RESIDENTIAL (MIXED USE) • 5,523 SF
Value Estimation
$1,030,000
70 Main St, Hopkinton, MA 01748-1307
View details
89 Hayden Rowe St

89 Hayden Rowe St

MIXED USE (COMMERCIAL/INDUSTRIAL) • 6,554 SF
Value Estimation
$1,115,000
89 Hayden Rowe St, Hopkinton, MA 01748-2507
View details
17 Main St

17 Main St

COMMERCIAL (GENERAL) • 0.46 Acres
Value Estimation
$825,000
17 Main St, Hopkinton, MA 01748-3211
View details
232-234 Wood St

232-234 Wood St

OFFICE/RESIDENTIAL (MIXED USE) • 4,023 SF
Value Estimation
$510,000
232-234 Wood St, Hopkinton, MA 01748
View details

Hopkinton, MA Commercial Real Estate Investment Opportunities Market Analysis

Explore 237 commercial real estate for sale in Hopkinton, MA, showcased through 7 active listings on our real estate platform. These investment opportunities span a total of 0 square feet of properties for sale, with an estimated market value of $0.00.

Sale prices for business properties in Hopkinton, MA start at $0.00, averaging $0.00, and reaching up to $0.00 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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