Hopkinton, MA Commercial Real Estate for Lease

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Southborough, MA Ashland, MA Westborough, MA
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Hopkinton Lab Space For Lease
Updated: Apr 22
Hopkinton Lab Space For Lease

100-106 South St, Hopkinton, MA 1748

$22 SF/Yr
6,000 sqft · $11,000/Mo
6,000 Sq. Ft. of lab space available
Located at 100‑106 South St in Hopkinton
Space available for lease
Year Built: 1900
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Hopkinton Office Space Available
Updated: May 21
Hopkinton Office Space Available

35 Parkwood Drive, Hopkinton, MA 1748

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41,437 sqft
41,437 SF office space available
Located in Hopkinton
Year Built: 2026
Office space for rent
New construction
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GMP Space Near I-495
GMP Space Near I-495

52 South Street, Hopkinton, MA 1748

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149,993 sqft

149,993 SF GMP space available for rent, can be subdivided.

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Office Building with Highway Access
Office Building with Highway Access

227-233 South Street, Hopkinton, MA 1748

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Well-located office space providing immediate access to I-495 and I-90.

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Hopkinton Flex Space Opportunity
Hopkinton Flex Space Opportunity

75 South St, Hopkinton, MA 1748

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Modern flex space with drive-in door and potential outdoor storage.

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Hopkinton Flex/Manufacturing Space For Rent
Hopkinton Flex/Manufacturing Space For Rent

107-109 South St, Hopkinton, MA

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11,031 sqft

Flex/manufacturing space in Hopkinton Innovation Park, easy highway access.

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Based on your search, we've compiled 22 Potential Opportunities for your consideration. Besides 7 Active listings in Hopkinton, MA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 11 Properties for Sales.

Commercial real estate for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Professional Office Suite For Lease
Professional Office Suite For Lease

120 Quarry Dr 2nd fl, Milford, MA 1757

$16 SF/Yr

Second-floor office suite with flexible layout and regional accessibility.

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Flex Space on Route 85
Flex Space on Route 85

113 Cedar St, Milford, MA 1757

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3,260 sqft

Flex/R&D park with highway visibility and immediate highway access.

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Milford Office Space Available
Milford Office Space Available

83 Cedar St, Milford, MA

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50,000 sqft

50000 square feet of office space for rent.

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Milford Office Building For Lease
Milford Office Building For Lease

100 Cedar St, Milford, MA

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26,666 sqft

Office building with 26,666 SF available for lease.

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Similar Spaces for Sale in Hopkinton, MA

Consider Similar Space for Sale. We found 11 Spaces matching your search parameters.

Hopkinton Warehouse with Overhead Doors
Hopkinton Warehouse with Overhead Doors

85R Hayden Rowe, Hopkinton, MA 1748

$1,100,000

Warehouse with multiple overhead doors and sewer connection stub.

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Approved Medical Office Land
Approved Medical Office Land

28 Lumber St, Hopkinton, MA 1748

$850,000

Land approved for a 10,000 sq ft medical office.

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Hopkinton Land Site on Route 135
Hopkinton Land Site on Route 135

124 E Main St, Hopkinton, MA 1748

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7.29 AC lot

Prime 7.29 acre land site in affluent Hopkinton, MA.

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Laboratory Office Space
Laboratory Office Space

100-106 South St, Hopkinton, MA 1748

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6,000 sqft

6,000 sq. ft. lab space offered for lease, suited for lab-supporting office and research operations.

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Retail Storefront Near Marathon Start
Retail Storefront Near Marathon Start

66 Main Street |, Hopkinton, MA 1748

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Retail storefront with high visibility and ample parking.

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Modern Office Building Near Downtown
Modern Office Building Near Downtown

34 Hayden Rowe Street, Hopkinton, MA 1748

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46,857 sqft

Modern office spaces with first-class finishes and convenient location.

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Hopkinton Corner Lot Opportunity
Hopkinton Corner Lot Opportunity

290 West Main Street, Hopkinton, MA 1748

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2 sqft

2.32 acre corner lot near Route 495.

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Downtown Hopkinton Mixed-Use Development
Downtown Hopkinton Mixed-Use Development

52 Main Street, Hopkinton, MA 1748

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75,300 sqft

New mixed-use development with retail and residential units.

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Hopkinton Warehouse with Expansion Plans
Hopkinton Warehouse with Expansion Plans

71 Frankland Rd, Hopkinton, MA

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115,970 sqft · 30.20 AC lot

115,970 SF warehouse with expansion potential and heavy power.

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High-Visibility Corner Lot
High-Visibility Corner Lot

52 School St, Hopkinton, MA

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2.32 AC lot

Agricultural zoned land with high traffic and easy access.

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Prime Land Site on Route 135
Prime Land Site on Route 135

83 E Main St, Hopkinton, MA

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0.75 AC lot

Desirable .75 acre land site in affluent Hopkinton, MA.

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Hopkinton, MA Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Hopkinton, MA with 7 listings featured on our commercial real estate exchange. The current inventory includes 6,700 square feet of properties with an estimated lease value of $59 SF/Yr.

Estimated lease rates for Commercial real estate in Hopkinton, MA begin at $22 SF/Yr, with an average of $29 SF/Yr and extend to $37 SF/Yr.
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