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    546 properties
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    Veterinary Medical Clinic
    Updated: Sep 25
    Veterinary Medical Clinic

    3350 SE 82nd Street, Runnells, IA 50237

    $1,000,000
    6,394 sqft 2.87 AC lot
    Operating room, recovery room, and dedicated pharmacy build‑out
    Eight interior stalls and 4‑foot‑wide doorways for large animal access
    In‑floor radiant heat, two boiler systems, and dual crane lifts
    X‑ray lighting built into the walls, microbial floor coating, and integrated fly system
    2.87‑acre site with 5,920 SF of asphalt paving
    View details
    Strip Mall with Four Leased Spaces
    Updated: Sep 23
    Strip Mall with Four Leased Spaces

    307 8th Street SW, Altoona, IA 50009

    $1,400,000
    1.00 AC lot
    Four leased spaces in a multi‑tenant retail building
    6,320 sq ft of ground‑floor area and a 480 sq ft finished basement
    Adjoining parcel included in the sale
    C‑2 zoning
    Across from Hy‑Vee and near Walgreens on 8th Street
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    Four-Bay Auto Shop
    Four-Bay Auto Shop

    2603 Douglas Avenue, Des Moines, IA 50310

    $700,000
    0.73 AC lot

    A customer reception area, office, kitchenette, and restroom complement the service-bay layout.

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    Veterinary Medical Center
    Veterinary Medical Center

    3451 Hubbell Ave, Des Moines, IA 50317

    $985,000
    4,000 sqft

    Freestanding veterinary care facility with an NN lease structure and a five-year renewal option.

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    Mixed-Use Property with Two Buildings
    Mixed-Use Property with Two Buildings

    2312 Forest Avenue, Des Moines, IA 50311

    $200,000
    7,238 sqft 0.26 AC lot

    Two structures combine commercial space with residential redevelopment areas.

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    Flex Space with Warehouse
    Flex Space with Warehouse

    15201 Hickman Road, Clive, IA 50325

    $850,000
    0.66 AC lot

    Mixed commercial improvements combine office, showroom, warehouse, concrete parking, and fenced access on two parcels.

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    Storefront Property
    Storefront Property

    104 & 108 1st Street, West Des Moines, IA 50265

    $999,900
    0.20 AC lot

    Public water and sewer serve the site, which is zoned C.

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    Four-Suite Strip Mall
    Four-Suite Strip Mall

    307 8th St SW, Altoona, IA 50009

    $1,400,000
    6,320 sqft

    The multi-tenant building has C-2 General Commercial zoning and an adjoining parcel included in the sale.

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    Industrial Warehouse and Shop Buildings
    Industrial Warehouse and Shop Buildings

    6212 NE 14th Street, Des Moines, IA 50313

    $2,000,000
    7.99 AC lot

    Two industrial buildings combine warehouse, office, and shop space on a large LI-zoned parcel.

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    One-Story Office Building
    One-Story Office Building

    2721 SW 30th Street, Des Moines, IA 50321

    $565,000
    0.63 AC lot

    Professional layout includes private offices, conference space, a kitchen, and three restrooms for flexible office configurations.

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    High-Visibility Office Building
    High-Visibility Office Building

    2805 South Ankeny Boulevard, Ankeny, IA 50023

    $1,240,000
    4,106 sqft

    Turnkey office property with access to South Ankeny Boulevard, Oralabor Road, and Interstate 35.

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    C-2 Zoned Storefront Property
    C-2 Zoned Storefront Property

    6301 SW 9th Street, Des Moines, IA 50315

    $499,900
    0.30 AC lot

    Forced-air heating, central air, and public utilities serve this commercial property.

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    Agricultural Land with Ranch Home
    Agricultural Land with Ranch Home

    5917 SE 6th Avenue, Pleasant Hill, IA 50327

    $1,619,900
    68.00 AC lot

    Four-parcel tract includes prairie, mature walnut trees, a pond, and outbuildings.

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    Office Building Near Highway Access
    Office Building Near Highway Access

    1290 Copper Creek Drive, Pleasant Hill, IA 50327

    $3,050,000
    11,083 sqft 1.69 AC lot

    11,083-square-foot office property on 1.689 acres with nearby dining, recreation, and access to E. University Avenue and Highway 65.

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    Church Facility With Event Space
    Church Facility With Event Space

    3023 E 29th Street, Des Moines, IA 50317

    $474,900
    0.85 AC lot

    Brick construction, dedicated parking, and separate public restrooms support gatherings, programs, and community-oriented operations.

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    Private Office Unit
    Private Office Unit

    110 SE Grant Street, Ankeny, IA 50021

    $125,000
    0.05 AC lot

    C-1-zoned office unit with three enclosed rooms and a half bathroom.

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    Modern Medical Office Building
    Modern Medical Office Building

    8831 Windsor Parkway, Johnston, IA 50131

    $2,285,000
    7,459 sqft

    Newly constructed Class A office building with an efficient layout, high-end finishes, and ample on-site parking.

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    Agricultural Land with Road Access
    Agricultural Land with Road Access

    TBD NE 38th Street, Ankeny, IA 50021

    $2,103,310
    38.24 AC lot

    AT-zoned acreage under a cash-rent farm lease with hard-surface road access and an existing driveway area.

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    Standalone One-Story Office Building
    Standalone One-Story Office Building

    2721 SW 30th St, Des Moines, IA 50321

    $590,000
    3,868 sqft 0.63 AC lot

    Flexible professional layout with private offices, conference space, kitchen, and multiple restrooms.

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    Self-Service Car Wash with Multiple Bays
    Self-Service Car Wash with Multiple Bays

    3740 Easton Boulevard, Des Moines, IA 50317

    $200,000
    0.31 AC lot

    Established automotive service property with enclosed washing and vacuum areas.

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    Historic Court Avenue Retail Opportunity
    Historic Court Avenue Retail Opportunity

    310 Court Ave, Des Moines, IA 50309

    $1,350,000
    7,999 sqft

    Prime retail/restaurant space in Des Moines' historic Court District.

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    Five-Bay Car Wash
    Five-Bay Car Wash

    875 Sherrylynn Boulevard, Pleasant Hill, IA 50327

    $450,000
    0.48 AC lot

    Combination self-service and touchless equipment supports varied customer preferences, with vacuum stations included on the site.

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    Heavy Industrial Warehouse with Office
    Heavy Industrial Warehouse with Office

    4485 Northeast 22nd Street, Des Moines, IA 50313

    $2,150,000
    10,500 sqft 4.65 AC lot

    Warehouse with heavy industrial zoning, finished office space, and multiple loading doors for practical industrial operations.

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    Brick Church Building
    Brick Church Building

    224 SW 3rd Street, Ankeny, IA 50023

    $640,000
    0.35 AC lot

    Historic religious facility with sanctuary, classrooms, offices, and gathering areas.

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    Polk County, IA Commercial Real Estate Market Trends and Statistics

    Explore 546 commercial real estate for sale in Polk County, IA, showcased through 546 active listings on our real estate platform. These investment opportunities span a total of 15,080,055 square feet of properties for sale, with an estimated market value of $322,567,852.

    Sale prices for business properties in Polk County, IA start at $75,000, averaging $1,724,961, and reaching up to $18,661,200 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Featured Polk County Real Estate Agencies

    Realmo connects you with licensed Polk County CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

    Developers Realty Group
    3227 111th Street Urbandale, IA 50322
    Phone: (515) 278-2741
    developersrealtygroup.com
    Keller Williams Ankeny Metro
    1610 SW Mian Street, Suite 204 Ankeny, IA 50023
    Phone: (515) 965-9100
    Space Simply
    10306 Douglas Ave Urbandale, IA 50322
    Phone: (515) 556-9674
    www.greatdesmoineshomes.com
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