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Polk County, IA Medical Office Space for Lease

24 results
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University Avenue Commercial Space
$20 SF/Yr
2,687 SF

University Avenue Commercial Space

1250 Northwest 128th Street, Clive, IA 50325

Prime location for office, medical, or retail use.

  • Prime location on University Avenue in Clive's active medical & retail corridor.
  • High visibility and convenient access to daytime and evening demographics.
  • Anchored by RBC Wealth Management and Mandarin Grill, offering a dynamic mix of tenants.
  • Enjoy front‑door parking with visibility from University Avenue.
  • Attractive brick/masonry construction.
Updated: Mar 25
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Polk City Commercial Space Available
$16 SF/Yr
3,636 SF

Polk City Commercial Space Available

1420 West Broadway Street, Polk City, IA 50226

Versatile commercial space in Polk City, suitable for various uses.

  • High Visibility Along Broadway St
  • Easy Access to Local & Regional Traffic
  • Open Layout
  • On‑Site Parking
  • Large Outdoor Area On‑Site
Updated: Mar 25
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Versatile Space in Clive Business Park
$12 SF/Yr
11,979 SF

Versatile Space in Clive Business Park

Adaptable space suitable for retail, office, or medical uses.

2555 Berkshire Pkwy, Clive, IA 50325
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High Visibility Retail/Office Space
$15 SF/Yr
6,650 SF

High Visibility Retail/Office Space

Retail or medical office space in a high-traffic location.

6201 Southeast 14th Street, Des Moines, IA 50320
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Medical Office Space Available
$16 SF/Yr

Medical Office Space Available

Class A medical space in the heart of Medical Mile.

5901 Westown Parkway, West Des Moines, IA 50266
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Medical Office Space Available
$9 SF/Yr

Medical Office Space Available

Former orthodontics office with operatories, lab, and private offices.

7180 Hickman Road, Windsor Heights, IA 50324
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Medical Suite in Des Moines
$18 SF/Yr
2,247 SF

Medical Suite in Des Moines

Medical suite for lease within Methodist Medical Center Campus.

1215-1415 Pleasant St, Des Moines, IA
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Des Moines Medical Office Space
$22 SF/Yr
7,572 SF

Des Moines Medical Office Space

Medical office space in Des Moines' major medical corridor.

330 Laurel Street, Des Moines, IA 50314
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West Des Moines Office Space
$13 SF/Yr
3,736 SF

West Des Moines Office Space

Versatile office space in high-traffic West Des Moines corridor.

1701 22nd St, West Des Moines, IA
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Johnston Office or Retail Space
$22 SF/Yr
1,400 SF

Johnston Office or Retail Space

Office or retail space in Johnston near professional offices.

5705 Northwest 100th Street, Johnston, IA 50131
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Johnston Office Space For Lease
Contact for pricing
4,259 SF

Johnston Office Space For Lease

Medical/Professional office space available in Johnston, Iowa.

6105 Northwest 86th Street, Johnston, IA 50131
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Fleur Drive Retail/Medical Space
$15 SF/Yr
2,275 SF

Fleur Drive Retail/Medical Space

Well-maintained retail or medical space in a high-traffic area.

4214 Fleur Dr, Des Moines, IA
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Renovated Office Building in Sherman Hills
$22 SF/Yr
2,217 SF

Renovated Office Building in Sherman Hills

Historically renovated office building suitable for office or medical use.

800 19th St, Des Moines, IA
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Ankeny Medical Office Space Available
$23 SF/Yr
2,352 SF

Ankeny Medical Office Space Available

Freestanding medical office building in Ankeny submarket for lease.

800 East 1st Street, Ankeny, IA 50021
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West Des Moines Commercial Space
$15 SF/Yr
1,850 SF

West Des Moines Commercial Space

Commercial space available south of I-235 in West Des Moines.

1300 50th St, West Des Moines, IA 50266
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Turnkey Medical Space in Clive
$17 SF/Yr
2,463 SF

Turnkey Medical Space in Clive

Move-in ready medical space in a growing healthcare corridor.

1601 NW 114th St, Clive, IA
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Medical Office Space Available
Contact for pricing
9,608 SF

Medical Office Space Available

Medical office building with on-site parking in high-traffic area.

1530 E Euclid Ave, Des Moines, IA 50313
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Medical Office Space Available
$15 SF/Yr
1,413 SF

Medical Office Space Available

Ready-to-use medical suite with ample parking and prime location.

1031 Office Park Rd, West Des Moines, IA 50265
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Medical Surgery Center For Lease
Contact for pricing
24,000 SF

Medical Surgery Center For Lease

Class A medical surgery center adjacent to Mercy One Medical Center.

450 Laurel St, Des Moines, IA 50314
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Office/Medical Suites For Rent
Contact for pricing
5,073 SF

Office/Medical Suites For Rent

Office and medical suites available in West Des Moines, Iowa.

1031 Office Park Rd, West Des Moines, IA 50265
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Medical Surgery Center for Lease
Contact for pricing
24,000 SF

Medical Surgery Center for Lease

Class A medical surgery center space available for lease.

450 Laurel St, Des Moines, IA 50314
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Medical Building in Pleasant Hill
$20 SF/Yr
2,793 SF

Medical Building in Pleasant Hill

Multi-tenant medical building located in Mercy One Pleasant Hill Campus.

5900 E University Ave, Pleasant Hill, IA
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Des Moines Office Space Available
Contact for pricing
2,000 SF

Des Moines Office Space Available

Office space available for lease in Des Moines, Iowa.

4919 Douglas Ave, Des Moines, IA 50310
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Medical Office Space Available
Contact for pricing

Medical Office Space Available

Medical office space with six offices, break room, and restroom.

1300 50th St, West Des Moines, IA 50266
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Based on your search, we've compiled 24 Potential Opportunities for your consideration. Besides 24 Active listings in Polk County, IA, we suggest exploring alternatives.

Polk County, IA Medical Office Space Leasing Opportunities Market Analysis

Explore Medical Office Space leasing options in Polk County, IA with 24 listings featured on our commercial real estate exchange. The current inventory includes 1,819,893,240 square feet of properties with an estimated lease value of $170 SF/Yr.

Estimated lease rates for Medical Office Space in Polk County, IA begin at $15 SF/Yr, with an average of $18 SF/Yr and extend to $23 SF/Yr.
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