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    26 properties
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    Medical Office Building with Parking
    Updated: Jun 23
    Medical Office Building with Parking

    1530 East Euclid Avenue, Des Moines, IA 50313

    $15 SF/Yr
    9,608 sqft $12,010/Mo
    Well‑maintained medical office building with up to 9,608 SF total space
    1.074‑acre lot with on‑site parking for office and medical use
    Includes private exam rooms and offices
    Dedicated lab space plus storage areas
    Available monument signage
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    University Avenue Commercial Space
    Updated: Mar 25
    University Avenue Commercial Space

    1250 Northwest 128th Street, Clive, IA 50325

    $20 SF/Yr
    2,687 sqft $4,478/Mo
    Prime location on University Avenue in Clive's active medical & retail corridor.
    High visibility and convenient access to daytime and evening demographics.
    Anchored by RBC Wealth Management and Mandarin Grill, offering a dynamic mix of tenants.
    Enjoy front‑door parking with visibility from University Avenue.
    Attractive brick/masonry construction.
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    Medical Office Building
    Medical Office Building

    6601 SW 9th St, Des Moines, IA 50315

    $23 SF/Yr
    22,572 sqft $43,263/Mo

    Medical office space with built-out examination rooms, multiple waiting areas, and ample on-site parking.

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    Versatile Space in Clive Business Park
    Versatile Space in Clive Business Park

    2555 Berkshire Pkwy, Clive, IA 50325

    $12.50 SF/Yr
    11,979 sqft $12,478/Mo

    Adaptable space suitable for retail, office, or medical uses.

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    Johnston Office or Retail Space
    Johnston Office or Retail Space

    5705 Northwest 100th Street, Johnston, IA 50131

    $22 SF/Yr
    1,400 sqft $2,566/Mo

    Office or retail space in Johnston near professional offices.

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    Renovated Office Building in Sherman Hills
    Renovated Office Building in Sherman Hills

    800 19th St, Des Moines, IA

    $22 SF/Yr
    2,217 sqft $4,064/Mo

    Historically renovated office building suitable for office or medical use.

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    West Des Moines Medical Office
    West Des Moines Medical Office

    6000 University Avenue, West Des Moines, IA 50266

    $20 SF/Yr
    2,327 sqft $3,878/Mo

    Established medical office space for rent in West Des Moines.

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    Grand Avenue Office and Clinic
    Grand Avenue Office and Clinic

    3200 Grand Avenue, Des Moines, IA 50312

    $22 SF/Yr
    152,854 sqft $280,232/Mo

    First-class office and clinic space with parking ramp.

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    Des Moines Medical Office Space
    Des Moines Medical Office Space

    330 Laurel Street, Des Moines, IA 50314

    $22 SF/Yr
    7,572 sqft $13,882/Mo

    Medical office space in Des Moines' major medical corridor.

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    Ankeny Medical Office Space Available
    Ankeny Medical Office Space Available

    800 East 1st Street, Ankeny, IA 50021

    $23.50 SF/Yr
    2,352 sqft $4,606/Mo

    Freestanding medical office building in Ankeny submarket for lease.

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    Fleur Drive Retail/Medical Space
    Fleur Drive Retail/Medical Space

    4214 Fleur Dr, Des Moines, IA

    $15 SF/Yr
    2,275 sqft $2,843/Mo

    Well-maintained retail or medical space in a high-traffic area.

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    Medical Office Space Available
    Medical Office Space Available

    5901 Westown Parkway, West Des Moines, IA 50266

    $16 SF/Yr

    Class A medical space in the heart of Medical Mile.

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    West Des Moines Office Space
    West Des Moines Office Space

    1701 22nd St, West Des Moines, IA

    $13 SF/Yr
    3,736 sqft $4,047/Mo

    Versatile office space in high-traffic West Des Moines corridor.

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    Medical Office Space in Clive
    Medical Office Space in Clive

    1449 Northwest 128th Street, Clive, IA 50325

    Contact for pricing
    17,710 sqft

    Premier medical office space within the MercyOne medical campus.

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    Medical Office Space Available
    Medical Office Space Available

    7180 Hickman Road, Windsor Heights, IA 50324

    $9 SF/Yr

    Former orthodontics office with operatories, lab, and private offices.

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    Johnston Office Space For Lease
    Johnston Office Space For Lease

    6105 Northwest 86th Street, Johnston, IA 50131

    Contact for pricing
    4,259 sqft

    Medical/Professional office space available in Johnston, Iowa.

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    Turnkey Medical Space in Clive
    Turnkey Medical Space in Clive

    1601 NW 114th St, Clive, IA 50325

    Contact for pricing
    2,753 sqft

    Move-in ready medical space in a growing healthcare corridor.

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    Brand-New Flexible Retail/Office Suites
    Brand-New Flexible Retail/Office Suites

    1220 NE Station Xing, Grimes, IA 50111

    Contact for pricing

    Newly constructed suites with flexible sizes, ample parking, and easy access from Highway 141 for retail, office, medical, and service uses.

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    Office/Medical Suites For Rent
    Office/Medical Suites For Rent

    1031 Office Park Rd, West Des Moines, IA 50265

    $15.50 SF/Yr
    5,073 sqft $6,552/Mo

    Office and medical suites available in West Des Moines, Iowa.

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    Medical Office Space Available
    Medical Office Space Available

    1031 Office Park Rd, West Des Moines, IA 50265

    $15.50 SF/Yr
    1,413 sqft $1,825/Mo

    Ready-to-use medical suite with ample parking and prime location.

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    Des Moines Office Space Available
    Des Moines Office Space Available

    4919 Douglas Ave, Des Moines, IA 50310

    $12 SF/Yr
    2,000 sqft $2,000/Mo

    Office space available for lease in Des Moines, Iowa.

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    Medical Surgery Center For Lease
    Medical Surgery Center For Lease

    450 Laurel St, Des Moines, IA 50314

    Contact for pricing
    24,000 sqft

    Class A medical surgery center adjacent to Mercy One Medical Center.

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    West Des Moines Commercial Space
    West Des Moines Commercial Space

    1300 50th St, West Des Moines, IA 50266

    $14 SF/Yr
    1,850 sqft $2,158/Mo

    Commercial space available south of I-235 in West Des Moines.

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    Medical Building in Pleasant Hill
    Medical Building in Pleasant Hill

    5900 E University Ave, Pleasant Hill, IA

    $20 SF/Yr
    2,793 sqft $4,655/Mo

    Multi-tenant medical building located in Mercy One Pleasant Hill Campus.

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    Polk County, IA Medical Office Space Market Trends and Statistics

    Explore Medical Office Space leasing options in Polk County, IA with 26 listings featured on our commercial real estate exchange. The current inventory includes 234,708 square feet of properties with an estimated lease value of $307 /Mo.

    Estimated lease rates for Medical Office Space in Polk County, IA begin at $12 SF/Yr, with an average of $18.06 SF/Yr and extend to $23.50 SF/Yr.
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