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    Polk County, IA Medical Office Space for Lease

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    Des Moines, IA Cedar Rapids, IA West Des Moines, IA
    25 results
    University Avenue Commercial Space
    $20 SF/Yr
    2,687 SF

    University Avenue Commercial Space

    1250 Northwest 128th Street, Clive, IA 50325

    Prime location for office, medical, or retail use.

    • Prime location on University Avenue in Clive's active medical & retail corridor.
    • High visibility and convenient access to daytime and evening demographics.
    • Anchored by RBC Wealth Management and Mandarin Grill, offering a dynamic mix of tenants.
    • Enjoy front‑door parking with visibility from University Avenue.
    • Attractive brick/masonry construction.
    Updated: Mar 25
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    Polk City Commercial Space Available
    $16 SF/Yr
    3,636 SF

    Polk City Commercial Space Available

    1420 West Broadway Street, Polk City, IA 50226

    Versatile commercial space in Polk City, suitable for various uses.

    • High Visibility Along Broadway St
    • Easy Access to Local & Regional Traffic
    • Open Layout
    • On‑Site Parking
    • Large Outdoor Area On‑Site
    Updated: Mar 25
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    Versatile Space in Clive Business Park
    $12 SF/Yr
    11,979 SF

    Versatile Space in Clive Business Park

    Adaptable space suitable for retail, office, or medical uses.

    2555 Berkshire Pkwy, Clive, IA 50325
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    High Visibility Retail/Office Space
    $15 SF/Yr
    6,650 SF

    High Visibility Retail/Office Space

    Retail or medical office space in a high-traffic location.

    6201 Southeast 14th Street, Des Moines, IA 50320
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    Johnston Office or Retail Space
    $22 SF/Yr
    1,400 SF

    Johnston Office or Retail Space

    Office or retail space in Johnston near professional offices.

    5705 Northwest 100th Street, Johnston, IA 50131
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    Medical Suite in Des Moines
    $18 SF/Yr
    2,247 SF

    Medical Suite in Des Moines

    Medical suite for lease within Methodist Medical Center Campus.

    1215-1415 Pleasant St, Des Moines, IA
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    Medical Office Space in Clive
    Contact for pricing
    17,710 SF

    Medical Office Space in Clive

    Premier medical office space within the MercyOne medical campus.

    1449 Northwest 128th Street, Clive, IA 50325
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    West Des Moines Office Space
    $13 SF/Yr
    3,736 SF

    West Des Moines Office Space

    Versatile office space in high-traffic West Des Moines corridor.

    1701 22nd St, West Des Moines, IA
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    West Des Moines Medical Office
    $20 SF/Yr
    2,327 SF

    West Des Moines Medical Office

    Established medical office space for rent in West Des Moines.

    6000 University Avenue, West Des Moines, IA 50266
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    Grand Avenue Office and Clinic
    $22 SF/Yr
    152,854 SF

    Grand Avenue Office and Clinic

    First-class office and clinic space with parking ramp.

    3200 Grand Avenue, Des Moines, IA 50312
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    Des Moines Medical Office Space
    $22 SF/Yr
    7,572 SF

    Des Moines Medical Office Space

    Medical office space in Des Moines' major medical corridor.

    330 Laurel Street, Des Moines, IA 50314
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    Fleur Drive Retail/Medical Space
    $15 SF/Yr
    2,275 SF

    Fleur Drive Retail/Medical Space

    Well-maintained retail or medical space in a high-traffic area.

    4214 Fleur Dr, Des Moines, IA
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    Turnkey Medical Space in Clive
    Contact for pricing
    2,753 SF

    Turnkey Medical Space in Clive

    Move-in ready medical space in a growing healthcare corridor.

    1601 NW 114th St, Clive, IA 50325
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    Renovated Office Building in Sherman Hills
    $22 SF/Yr
    2,217 SF

    Renovated Office Building in Sherman Hills

    Historically renovated office building suitable for office or medical use.

    800 19th St, Des Moines, IA
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    Johnston Office Space For Lease
    Contact for pricing
    4,259 SF

    Johnston Office Space For Lease

    Medical/Professional office space available in Johnston, Iowa.

    6105 Northwest 86th Street, Johnston, IA 50131
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    West Des Moines Commercial Space
    $15 SF/Yr
    1,850 SF

    West Des Moines Commercial Space

    Commercial space available south of I-235 in West Des Moines.

    1300 50th St, West Des Moines, IA 50266
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    Medical Office Space Available
    $16 SF/Yr

    Medical Office Space Available

    Class A medical space in the heart of Medical Mile.

    5901 Westown Parkway, West Des Moines, IA 50266
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    Medical Office Space Available
    $9 SF/Yr

    Medical Office Space Available

    Former orthodontics office with operatories, lab, and private offices.

    7180 Hickman Road, Windsor Heights, IA 50324
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    Medical Office Space Available
    Contact for pricing
    9,608 SF

    Medical Office Space Available

    Medical office building with on-site parking in high-traffic area.

    1530 E Euclid Ave, Des Moines, IA 50313
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    Medical Office Space Available
    $15 SF/Yr
    1,413 SF

    Medical Office Space Available

    Ready-to-use medical suite with ample parking and prime location.

    1031 Office Park Rd, West Des Moines, IA 50265
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    Office/Medical Suites For Rent
    $15 SF/Yr
    5,073 SF

    Office/Medical Suites For Rent

    Office and medical suites available in West Des Moines, Iowa.

    1031 Office Park Rd, West Des Moines, IA 50265
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    Medical Surgery Center For Lease
    Contact for pricing
    24,000 SF

    Medical Surgery Center For Lease

    Class A medical surgery center adjacent to Mercy One Medical Center.

    450 Laurel St, Des Moines, IA 50314
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    Des Moines Office Space Available
    $12 SF/Yr
    2,000 SF

    Des Moines Office Space Available

    Office space available for lease in Des Moines, Iowa.

    4919 Douglas Ave, Des Moines, IA 50310
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    Medical Building in Pleasant Hill
    $20 SF/Yr
    2,793 SF

    Medical Building in Pleasant Hill

    Multi-tenant medical building located in Mercy One Pleasant Hill Campus.

    5900 E University Ave, Pleasant Hill, IA
    View details

    Polk County, IA Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Polk County, IA with 25 listings featured on our commercial real estate exchange. The current inventory includes 62,343 square feet of properties with an estimated lease value of $294 SF/Yr.

    Estimated lease rates for Medical Office Space in Polk County, IA begin at $12 SF/Yr, with an average of $17 SF/Yr and extend to $23 SF/Yr.
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