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    Seminole County, FL Mixed-use Properties for Sale

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    Miami, FL Tampa, FL Jacksonville, FL
    24 results
    Versatile Estate on Usable Acres
    $1,799,000
    7,675 SF

    Versatile Estate on Usable Acres

    1498 MARKHAM WOODS ROAD, Longwood, FL 32779

    Spacious Longwood estate suitable for residential, institutional, or community use.

    • 5.26 fully usable acres, privately gated, offering privacy and security.
    • Boasting 7,600+ square feet of combined interior space with up to 10 bedrooms and 9 bathrooms.
    • Exceptional flexibility for permitted uses: group home, school, daycare, church, community center, agricultural support, or multi‑family.
    • Features multiple dedicated office rooms, two fully equipped kitchens, and a spacious dining hall.
    • Enjoy large outdoor gathering areas, covered outdoor kitchen, and expansive lawn areas.
    Updated: Apr 19
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    Versatile Sanford Commercial Complex
    $825,000
    4,493 SF

    Versatile Sanford Commercial Complex

    2516 SANFORD AVENUE, Sanford, FL 32773

    Three-building complex with restaurant, live/work space, and flex building.

    • Prime location near the intersection of Sanford Ave and 25th St, a high‑traffic commercial corridor.
    • Three buildings on 0.71 acres offering multiple income streams and business opportunities.
    • Building 1: A 2,583 SF turnkey restaurant with existing equipment included.
    • Building 2: Unique live/work space with a 400 SF apartment above 400 SF of flex space.
    • Building 3: 1,110 SF flex building adaptable for various uses.
    Updated: Dec 2, 2025
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    Remodeled Historic Sanford Mixed-Use Building
    $2,000,000
    7,987 SF

    Remodeled Historic Sanford Mixed-Use Building

    Remodeled historic mixed-use building in Downtown Sanford's vibrant First Street.

    121 E 1ST STREET, Sanford, FL 32771
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    Casselberry Mixed-Use Investment Opportunity
    $330,900
    924 SF

    Casselberry Mixed-Use Investment Opportunity

    Flexible mixed-use property with redevelopment potential on a 0.36-acre lot.

    82 CONCORD DRIVE, Casselberry, FL 32707
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    Sanford Mixed-Use Commercial Opportunity
    $269,000
    1,332 SF

    Sanford Mixed-Use Commercial Opportunity

    Versatile commercial space in Sanford with high visibility and parking.

    1013 HISTORIC GOLDSBORO BOULEVARD, Sanford, FL 32771
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    Versatile Mixed-Use Commercial Property
    $1,590,000
    4,900 SF

    Versatile Mixed-Use Commercial Property

    Commercial property ideal for retail, office, or showroom uses.

    141 PARLIAMENT LOOP, Lake Mary, FL 32746
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    Versatile Sanford Commercial Complex
    $825,000
    4,493 SF

    Versatile Sanford Commercial Complex

    Three-building complex with restaurant, live/work unit, and flex space.

    2516 SANFORD AVENUE, Sanford, FL 32773
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    Altamonte Springs Multi-Tenant Property
    $765,000
    2,026 SF

    Altamonte Springs Multi-Tenant Property

    Fully leased office/retail property on State Road 436.

    1170 W STATE ROAD 436, Altamonte Springs, FL 32714
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    Mixed-Use Property with Redevelopment Potential
    $345,900
    0.36 Acres

    Mixed-Use Property with Redevelopment Potential

    Flexible mixed-use property on 0.36 acres, ideal for investors.

    82 CONCORD Dr, Casselberry, FL 32707
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    Sanford Commercial Space For Sale
    $289,000
    1,688 SF

    Sanford Commercial Space For Sale

    Versatile 1,688 SF commercial space with parking in Sanford, Florida.

    1013 HISTORIC GOLDSBORO Blvd, Sanford, FL 32771
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    Historic Mixed-Use Landmark in Sanford
    $2,000,000
    5,204 SF

    Historic Mixed-Use Landmark in Sanford

    Historic mixed-use building in Downtown Sanford with flexible configurations.

    101 W 1st St, Sanford, FL
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    Sanford Mixed-Use Opportunity
    $179,900
    720 SF

    Sanford Mixed-Use Opportunity

    Mixed-use property in Sanford's historic district, ready for new business.

    1006 S HISTORIC GOLDSBORO, Sanford, FL 32771
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    Sanford Commercial Space For Sale
    $299,000
    1,332 SF

    Sanford Commercial Space For Sale

    Versatile commercial space in Sanford, Florida with parking.

    1013 Historic Goldsboro Blvd, Sanford, FL 32771
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    Commercial Property on Orlando Drive
    $825,000
    1,716 SF

    Commercial Property on Orlando Drive

    Mixed-use commercial property with high traffic and flexible zoning.

    2606 S ORLANDO DRIVE, Sanford, FL 32773
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    Sanford Commercial/Mixed-Use Opportunity
    $349,900
    1,485 SF

    Sanford Commercial/Mixed-Use Opportunity

    Versatile commercial property near downtown Sanford with redevelopment potential.

    420 MONROE ROAD, Sanford, FL 32771
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    Downtown Sanford Mixed-Use Building
    $1,495,000
    4,930 SF

    Downtown Sanford Mixed-Use Building

    4,930 SF mixed-use building in Downtown Sanford, Florida.

    203 E 3rd St, Sanford, FL 32771
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    Historic Sanford Mixed-Use Opportunity
    $950,000
    6,032 SF

    Historic Sanford Mixed-Use Opportunity

    Mixed-use property in Sanford's Downtown Community Redevelopment Area.

    209 N OAK AVENUE, Sanford, FL 32771
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    Class A Medical/Retail Building
    Contact for pricing
    31,635 SF

    Class A Medical/Retail Building

    Premier building with investment or redevelopment potential in Altamonte Springs.

    460 E Altamonte Dr, Altamonte Springs, FL 32701
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    Income Producing Sanford Mixed-Use Property
    $1,000,000
    3,952 SF

    Income Producing Sanford Mixed-Use Property

    Income-producing mixed-use property in the heart of Sanford's Historic District.

    106 MAGNOLIA AVENUE, Sanford, FL 32771
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    Rehabbed Property with Redevelopment Potential
    $249,900
    882 SF

    Rehabbed Property with Redevelopment Potential

    Rehabbed commercial property, currently leased, with redevelopment potential.

    2882 Sanford Ave, Sanford, FL 32773
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    Retail Space in Mixed-Use Development
    Contact for pricing
    1,367 SF

    Retail Space in Mixed-Use Development

    Retail space for lease in Lake Mary mixed-use property.

    242 Wheelhouse Ln, Lake Mary, FL
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    Mixed-Use Property in Lake Mary
    Contact for pricing
    1,750 SF

    Mixed-Use Property in Lake Mary

    Premier mixed-use property with retail and luxury apartments.

    229 Wheelhouse Ln, Lake Mary, FL
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    Mixed-Use Property in Lake Mary
    Contact for pricing
    1,899 SF

    Mixed-Use Property in Lake Mary

    Premier mixed-use property with retail and luxury apartments in Florida.

    223 Wheelhouse Ln, Lake Mary, FL
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    19 Acre Lake Brian Property
    $2,275,000
    1,000 SF

    19 Acre Lake Brian Property

    24.77+ acre property with 19 acre private bass lake.

    4950 46A Road, Sanford, FL 32771
    View details
    Based on your search, we've compiled Potential Opportunities for your consideration. Besides 24 Active Listings in Seminole County, FL, we suggest to view alternatives - similar 48 Off-Market properties to explore as potential leads.

    Seminole County, FL Mixed-Use Properties Investment Opportunities Market Analysis

    Explore 72 mixed-use properties for sale in Seminole County, FL, showcased through 24 active listings on our real estate platform. These investment opportunities span a total of 61,771 square feet of properties for sale, with an estimated market value of $16,061,600.

    Sale prices for multi use buildings in Seminole County, FL start at $179,900, averaging $892,311, and reaching up to $2,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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