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    Seminole County, FL Mixed-use Properties for Sale

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    Five-Unit Mixed-Use Property
    Updated: Oct 12
    Five-Unit Mixed-Use Property

    585 S RONALD REAGAN Boulevard, Longwood, FL 32750

    $2,750,000
    13,800 sqft 1.62 AC lot
    Five units; two occupied and three vacant and available for lease
    1.62‑acre site with GC zoning
    Rubber membrane roof coating installed in 2023
    Unit 121 has new HVAC
    Sprinkler system in the child care and church unit
    View details
    Three-Building Mixed-Use Property
    Updated: Dec 2, 2025
    Three-Building Mixed-Use Property

    2516 SANFORD Avenue, Sanford, FL 32773

    $825,000
    4,493 sqft 0.71 AC lot
    Three‑building mixed‑use property totaling 4,493 square feet on 0.71 acres
    2,583 SF restaurant with existing equipment included
    400 SF 1‑bedroom/1‑bath apartment above 400 SF of open flex space
    1,110 SF flex building for storage, retail, service, or creative workspace
    General Commercial zoning designation: GC2
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    Updated Office Building
    Updated Office Building

    657 MAITLAND Avenue, Altamonte Springs, FL 32701

    $485,000
    1,518 sqft 0.27 AC lot

    A multi-room layout includes reception, conference, kitchen, flex space, restrooms, and dedicated parking.

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    Mixed-Use Building with Private Offices
    Mixed-Use Building with Private Offices

    121 E 1st St Unit 101, Sanford, FL 32771

    $1,500,000
    7,987 sqft

    A two-level configuration combines adaptable ground-floor space with a dedicated professional office layout upstairs.

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    Mixed-Use Building with Private Offices
    Mixed-Use Building with Private Offices

    121 E 1ST Street, Sanford, FL 32771

    $1,500,000
    7,987 sqft 0.10 AC lot

    Two levels combine an open commercial floor with a separate suite of private offices.

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    Mixed-Use Property with Road Frontage
    Mixed-Use Property with Road Frontage

    150 W 11TH Street, Chuluota, FL 32766

    $899,000
    1,962 sqft 0.96 AC lot

    C-2-zoned property combines commercial office space with a separate events venue in a two-story structure.

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    Mixed-Use Property with Parking
    Mixed-Use Property with Parking

    1013 HISTORIC GOLDSBORO Boulevard, Sanford, FL 32771

    $239,000
    1,332 sqft 0.16 AC lot

    GC2-zoned commercial building with flexible retail, office, mixed-use, and cultural facility applications.

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    Mixed-Use Commercial Complex
    Mixed-Use Commercial Complex

    2516 Sanford Ave, Sanford, FL 32773

    $825,000
    4,493 sqft 0.71 AC lot

    Three-building property combines restaurant, live/work, and flex-space components.

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    Historic Mixed-Use Building
    Historic Mixed-Use Building

    209 N OAK Avenue, Sanford, FL 32771

    $900,000
    6,032 sqft 0.10 AC lot

    SC3-zoned property supports retail, restaurant, office, and multifamily residential uses.

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    Renovated Live-Work Building
    Renovated Live-Work Building

    1150 N RONALD REAGAN BOULEVARD, Longwood, FL 32750

    $725,000
    2,540 sqft

    Two-story property combines professional office space with a residentially adaptable upper level and separate building systems.

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    Two-Suite Office Units
    Two-Suite Office Units

    104-111 Jewel Dr, Altamonte Springs, FL 32714

    $499,000
    1,392 sqft

    Separate entrances and private bathrooms support independent occupancy or a shared owner-user setup.

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    Two-Suite Mixed-Use Property
    Two-Suite Mixed-Use Property

    111 JEWEL DRIVE #104, Altamonte Springs, FL 32714

    $499,000
    1,000 sqft

    Separate entrances, private bathrooms, and a sizable yard support flexible commercial use.

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    5-Unit Mixed-Use Property
    5-Unit Mixed-Use Property

    585 S Ronald Reagan Boulevard, Unit 101, Longwood, FL 32750

    $2,750,000
    14,040 sqft

    Two occupied suites and three vacant units offer a mix of current tenancy and leasing availability.

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    Remodeled Historic Mixed-Use Building
    Remodeled Historic Mixed-Use Building

    121 E 1ST 101, Sanford, FL 32771

    $1,500,000

    Two-level layout combines open commercial space with private offices and support areas.

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    Historic Mixed-Use Building
    Historic Mixed-Use Building

    209 N OAK, Sanford, FL 32771

    $900,000

    SC-3 zoning supports retail, restaurant, office, and multifamily residential uses.

    View details
    Mixed-Use Property with Parking
    Mixed-Use Property with Parking

    1013 HISTORIC GOLDSBORO, Sanford, FL 32771

    $239,000

    General Commercial zoning supports several stated commercial and community-use possibilities.

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    Mixed-Use Property with Road Frontage
    Mixed-Use Property with Road Frontage

    150 W 11TH, Chuluota, FL 32766

    $899,000

    Multiple structures support office and event venue uses with access from two road-fronting corridors.

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    Commercial Sale / Mixed Use
    Commercial Sale / Mixed Use

    932 Country Club Road, Lake Mary, FL 32746

    $1,200,000
    780 sqft

    Commercial land · 780 SF

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    Downtown Sanford Mixed-Use Building
    Downtown Sanford Mixed-Use Building

    203 E 3rd St, Sanford, FL 32771

    Contact for pricing
    4,930 sqft

    4,930 SF mixed-use building in Downtown Sanford, Florida.

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    Grey Shell Mixed-Use Office
    Grey Shell Mixed-Use Office

    734 New Technology Blvd, Lake Mary, FL 32746

    Contact for pricing

    Grey shell medical or office space designed to support a range of tenant build-outs in Lake Mary.

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    Mixed-Use Property with Loading Doors
    Mixed-Use Property with Loading Doors

    112 N POPLAR AVE, Sanford, FL 32771

    Contact for pricing

    Multi-area building includes offices, warehouse space, and an upstairs residential unit.

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    Rehabbed Property with Redevelopment Potential
    Rehabbed Property with Redevelopment Potential

    2882 Sanford Ave, Sanford, FL 32773

    Contact for pricing
    882 sqft

    Rehabbed commercial property, currently leased, with redevelopment potential.

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    Two-Parcel Mixed-Use Property
    Two-Parcel Mixed-Use Property

    5650 Orange Blvd, Sanford, FL 32771

    Contact for pricing

    Includes agricultural land and an existing retail building under A-1 zoning.

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    19 Acre Lake Brian Property
    19 Acre Lake Brian Property

    4950 46A Road, Sanford, FL 32771

    Contact for pricing
    1,000 sqft 24.77 AC lot

    24.77+ acre property with 19 acre private bass lake.

    View details
    Not finding what you need? Try buying leads tailored to your intent and find the right opportunities before everyone else. Get Leads
    Based on your search, we've compiled Potential Opportunities for your consideration. Besides 24 Active Listings in Seminole County, FL, we suggest to view alternatives - similar 48 Off-Market properties to explore as potential leads.

    Seminole County, FL Mixed-Use Properties Market Trends and Statistics

    Explore 72 mixed-use properties for sale in Seminole County, FL, showcased through 24 active listings on our real estate platform. These investment opportunities span a total of 76,168 square feet of properties for sale, with an estimated market value of $19,134,000.

    Sale prices for multi use buildings in Seminole County, FL start at $239,000, averaging $1,063,000, and reaching up to $2,750,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Featured Seminole County Real Estate Agencies

    Realmo connects you with licensed Seminole County CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

    Lake Monroe Realty
    3840 Saint John's Parkway Sanford, FL 32771
    Phone: 14074023502
    lakemonroerealtyfl.com/
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