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    Seminole County, FL Mixed-use Properties for Sale

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    Lehigh Acres, FL Cape Coral, FL Port Charlotte, FL
    22 results
    Versatile Sanford Commercial Complex
    $825,000
    4,493 SF

    Versatile Sanford Commercial Complex

    2516 SANFORD AVENUE, Sanford, FL 32773

    Three-building complex with restaurant, live/work space, and flex building.

    • Prime location near the intersection of Sanford Ave and 25th St, a high‑traffic commercial corridor.
    • Three buildings on 0.71 acres offering multiple income streams and business opportunities.
    • Building 1: A 2,583 SF turnkey restaurant with existing equipment included.
    • Building 2: Unique live/work space with a 400 SF apartment above 400 SF of flex space.
    • Building 3: 1,110 SF flex building adaptable for various uses.
    Updated: Dec 2, 2025
    View details
    Remodeled Historic Sanford Mixed-Use Building
    $2,235,000
    7,987 SF

    Remodeled Historic Sanford Mixed-Use Building

    121 E 1ST STREET, Sanford, FL 32771

    Remodeled historic building in Downtown Sanford's vibrant First Street district.

    • Prime location in Downtown Sanford's First Street business district with high visibility.
    • Remodeled historic commercial building blending modern functionality with original character (exposed brick, soaring ceilings).
    • Versatile open‑concept first floor suitable for retail, restaurant, office, or event space.
    • Professionally designed second floor with eight private offices, a break room, and a restroom.
    • Recent upgrades including new LVP flooring, new carpet, fresh paint, and a new A/C system (2023).
    Updated: Oct 27, 2025
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    Casselberry Mixed-Use Investment Opportunity
    $340,900
    924 SF

    Casselberry Mixed-Use Investment Opportunity

    Mixed-use property with redevelopment potential on a 0.36-acre lot.

    82 CONCORD DRIVE, Casselberry, FL 32707
    View details
    Sanford Mixed-Use Commercial Opportunity
    $289,000
    1,332 SF

    Sanford Mixed-Use Commercial Opportunity

    Versatile commercial space in Sanford with high visibility and parking.

    1013 HISTORIC GOLDSBORO BOULEVARD, Sanford, FL 32771
    View details
    Prime Sanford Commercial/Mixed-Use Land
    $349,900
    0.76 Acres

    Prime Sanford Commercial/Mixed-Use Land

    Versatile commercial property near downtown Sanford with redevelopment potential.

    420 MONROE ROAD, Sanford, FL 32771
    View details
    Versatile Mixed-Use Commercial Property
    $1,590,000
    4,900 SF

    Versatile Mixed-Use Commercial Property

    Commercial property ideal for retail, office, or showroom uses.

    141 PARLIAMENT LOOP, Lake Mary, FL 32746
    View details
    Commercial Property on Orlando Drive
    $825,000
    1,716 SF

    Commercial Property on Orlando Drive

    Mixed-use commercial property with high traffic and flexible zoning.

    2606 S ORLANDO DRIVE, Sanford, FL 32773
    View details
    Versatile Sanford Commercial Complex
    $825,000
    4,493 SF

    Versatile Sanford Commercial Complex

    Three-building complex with restaurant, live/work unit, and flex space.

    2516 SANFORD AVENUE, Sanford, FL 32773
    View details
    Altamonte Springs Multi-Tenant Property
    $765,000
    2,026 SF

    Altamonte Springs Multi-Tenant Property

    Fully leased office/retail property on State Road 436.

    1170 W STATE ROAD 436, Altamonte Springs, FL 32714
    View details
    Mixed-Use Property with Redevelopment Potential
    $345,900
    0.36 Acres

    Mixed-Use Property with Redevelopment Potential

    Flexible mixed-use property on 0.36 acres, ideal for investors.

    82 CONCORD Dr, Casselberry, FL 32707
    View details
    Historic Mixed-Use Landmark in Sanford
    $2,000,000
    5,204 SF

    Historic Mixed-Use Landmark in Sanford

    Historic mixed-use building in Downtown Sanford with flexible configurations.

    101 W 1st St, Sanford, FL
    View details
    Sanford Mixed-Use Property For Sale
    $179,900
    720 SF

    Sanford Mixed-Use Property For Sale

    Mixed-use property in Sanford, close to downtown and airport.

    1006 S HISTORIC GOLDSBORO, Sanford, FL 32771
    View details
    Sanford Commercial/Mixed-Use Opportunity
    $349,900
    1,485 SF

    Sanford Commercial/Mixed-Use Opportunity

    Versatile commercial property near downtown Sanford with redevelopment potential.

    420 MONROE ROAD, Sanford, FL 32771
    View details
    Sanford Commercial Space For Sale
    $299,000
    1,332 SF

    Sanford Commercial Space For Sale

    Versatile commercial space in Sanford, Florida with parking.

    1013 Historic Goldsboro Blvd, Sanford, FL 32771
    View details
    Downtown Sanford Mixed-Use Building
    $1,495,000
    4,930 SF

    Downtown Sanford Mixed-Use Building

    4,930 SF mixed-use building in Downtown Sanford, Florida.

    203 E 3rd St, Sanford, FL 32771
    View details
    Historic Sanford Mixed-Use Opportunity
    $950,000
    6,032 SF

    Historic Sanford Mixed-Use Opportunity

    Mixed-use property in Sanford's Downtown Community Redevelopment Area.

    209 N OAK AVENUE, Sanford, FL 32771
    View details
    Class A Medical/Retail Building
    Contact for pricing
    31,635 SF

    Class A Medical/Retail Building

    Premier building with investment or redevelopment potential in Altamonte Springs.

    460 E Altamonte Dr, Altamonte Springs, FL 32701
    View details
    Retail Space in Mixed-Use Development
    Contact for pricing
    1,367 SF

    Retail Space in Mixed-Use Development

    Retail space for lease in Lake Mary mixed-use property.

    242 Wheelhouse Ln, Lake Mary, FL
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    Income Producing Sanford Mixed-Use Property
    $1,000,000
    3,952 SF

    Income Producing Sanford Mixed-Use Property

    Income-producing mixed-use property in the heart of Sanford's Historic District.

    106 MAGNOLIA AVENUE, Sanford, FL 32771
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    Rehabbed Property with Redevelopment Potential
    $249,900
    882 SF

    Rehabbed Property with Redevelopment Potential

    Rehabbed commercial property, currently leased, with redevelopment potential.

    2882 Sanford Ave, Sanford, FL 32773
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    Mixed-Use Property in Lake Mary
    Contact for pricing
    1,750 SF

    Mixed-Use Property in Lake Mary

    Premier mixed-use property with retail and luxury apartments.

    229 Wheelhouse Ln, Lake Mary, FL
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    Mixed-Use Property in Lake Mary
    Contact for pricing
    1,899 SF

    Mixed-Use Property in Lake Mary

    Premier mixed-use property with retail and luxury apartments in Florida.

    223 Wheelhouse Ln, Lake Mary, FL
    View details
    Based on your search, we've compiled Potential Opportunities for your consideration. Besides 22 Active Listings in Seminole County, FL, we suggest to view alternatives - similar 127 Off-Market properties to explore as potential leads.

    Explore Off-Market Properties in Seminole County, FL

    Consider similar Off-Market properties in Seminole County, FL. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    2509 Park Dr

    2509 Park Dr

    OFFICE/RESIDENTIAL (MIXED USE) • 2,948 SF
    Value Estimation
    $995,000
    2509 Park Dr, Sanford, FL 32773-5106
    View details
    761 Maitland Ave

    761 Maitland Ave

    OFFICE/RESIDENTIAL (MIXED USE) • 1,464 SF
    Value Estimation by Request
    761 Maitland Ave, Altamonte Springs, FL 32701-6835
    View details

    Seminole County, FL Mixed-Use Properties Investment Opportunities Market Analysis

    Explore 149 mixed-use properties for sale in Seminole County, FL, showcased through 22 active listings on our real estate platform. These investment opportunities span a total of 4,009,692 square feet of properties for sale, with an estimated market value of $43,509,700.

    Sale prices for multi use buildings in Seminole County, FL start at $85,000, averaging $457,996, and reaching up to $2,235,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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