Santa Cruz County, AZ Commercial Real Estate for Sale

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Found 67 commercial real estate listings for sale in Santa Cruz County, AZ, averaging $171/sq ft. Use valuation data to compare deals faster.
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Mixed-Use Property with Gallery
Updated: Sep 10
Mixed-Use Property with Gallery

2023 E Frontage Road, Tumacacori, AZ 85640

$345,000
2,303 sqft 0.39 AC lot
2,303‑square‑foot property with 1,120‑square‑foot gallery and 1,183‑square‑foot residence
Independent utility meters for the commercial and residential areas
1920 construction; burnt adobe; zoned SCC - B‑2
0.39‑acre fenced and gated site with two‑car detached garage, two storage sheds, oversized carport and RV parking
Private well, septic tank, updated roofs and new carpet in the home
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Mixed-Use Property with Gallery
Updated: Sep 10
Mixed-Use Property with Gallery

2023 E Frontage Road, Tumacacori, AZ 85640

$345,000
2,303 sqft 0.39 AC lot
Front gallery/studio measures 1,120 square feet; rear residence measures 1,183 square feet
2,303 square feet of total property area on 0.39 acres
Separate utility meters for the commercial and residential spaces
Detached two‑car garage, two storage sheds, oversized carport, and RV parking
1920 construction with burnt adobe and stucco
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Mixed-Use Property with Covered Terrace
Mixed-Use Property with Covered Terrace

37 Tubac Road, Tubac, AZ 85646

$450,000
2,037 sqft 0.17 AC lot

A flexible interior currently accommodates a craft and art supply shop alongside residential-scale amenities.

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NNN Retail Center with AutoZone Anchor
NNN Retail Center with AutoZone Anchor

166 N Grand Ave, Nogales, AZ 85621

$1,320,000
13,351 sqft

Multi-tenant NNN retail property is 100% occupied and anchored by an AutoZone tenant.

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Vineyard with On-Site Winery
Vineyard with On-Site Winery

90 Elgin Road, Elgin, AZ 85611

$4,250,000
9,848 sqft 28.73 AC lot

Fourteen grape varieties are cultivated, with wine produced on the estate.

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Mixed-Use Property with Casita
Mixed-Use Property with Casita

35 Tubac Road, Tubac, AZ 85646

$450,000
1,678 sqft 0.22 AC lot

A one-bedroom, one-bath residence includes a casita with its own entrance for flexible additional space.

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Five-Unit Retail Center
Five-Unit Retail Center

28800 S Nogales Highway, Amado, AZ 85645

$150,000
3,461 sqft 0.52 AC lot

Corner commercial property with Pima County GR1 zoning and access near Interstate 10 in Amado.

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Restaurant Property with Additional Land
Restaurant Property with Additional Land

180 W Loma St, Nogales, AZ 85621

$475,000
6,765 sqft

Existing restaurant improvements are offered with additional land and contents, without the operating business or liquor license.

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Multi-Tenant Shopping Center
Multi-Tenant Shopping Center

441 N Grand Avenue, Nogales, AZ 85621

$2,400,000
37,482 sqft 2.06 AC lot

Retail and office suites are arranged alongside a separate hub, serving a varied commercial tenant mix.

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Historic Ranch with Equestrian Facilities
Historic Ranch with Equestrian Facilities

277 Canelo Road, Elgin, AZ 85611

$2,500,000
11,196 sqft 82.98 AC lot

Updated units accompany an adobe manor and dedicated equestrian improvements.

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Remodeled Resort and Event Venue
Remodeled Resort and Event Venue

69 Abc Road, Patagonia, AZ 85624

$1,425,000
5,707 sqft 24.58 AC lot

Furnished hospitality property with multiple lodging buildings, event facilities, outdoor gathering areas, and established short-term rental operations.

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Eight-Unit Office Complex
Eight-Unit Office Complex

3129-1 Highway 83 Sonoita, Sonoita, AZ 85637

$485,000
4,240 sqft 0.93 AC lot

Remodeled offices and shared restrooms serve a multi-tenant layout with covered outdoor space.

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Mixed-Use Property with Retail
Mixed-Use Property with Retail

152 N Terrace Avenue, Nogales, AZ 85621

$6,000,000
24,910 sqft 1.72 AC lot

The property combines a large-format retail building with office/apartment space and on-site parking.

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Mixed-Use Property with Gallery
Mixed-Use Property with Gallery

2023 E Frontage Rd, Tumacacori, AZ 85640

$345,000
2,303 sqft

Historic adobe property combines a commercial gallery with a separate residence, utility meters, parking, storage, and gated access.

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Industrial Land with Highway Access
Industrial Land with Highway Access

3175 N Silver Hill Drive, Nogales, AZ 85621

$160,000
3.07 AC lot

Industrial-zoned acreage with on-site water and electric service, frontage road access, and room for future development.

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Cattle Grazing Ranch Land
Cattle Grazing Ranch Land

E Greaterville Road, Sonoita, AZ 85637

$1,224,270
174.91 AC lot

Ranch property with cattle grazing, barbed-wire fencing, and multiple potential building sites.

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Mixed-Use Property with Covered Terrace
Mixed-Use Property with Covered Terrace

37 Tubac Rd, Tubac, AZ 85646

$450,000
2,037 sqft

A flexible Tubac property combines residential and commercial zoning with a full kitchen and multiple interior rooms.

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Short-Term Rental Compound with Lodge
Short-Term Rental Compound with Lodge

69 ABC Road, Patagonia, AZ 85624

$1,425,000

A furnished, remodeled rural property combines guest lodging, event space, and a commercial kitchen across separate buildings.

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Live-Work Property with Casita
Live-Work Property with Casita

35 Tubac Rd, Tubac, AZ 85646

$450,000
1,678 sqft

A separate-entry casita accompanies the one-bedroom residence, providing distinct additional space.

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Conventional Restaurant Building with Equipment
Conventional Restaurant Building with Equipment

3280 Highway 82, Sonoita, AZ 85637

$295,000
1,544 sqft 0.25 AC lot

Existing restaurant improvements include equipment, central air, and a ramped accessible approach.

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Mixed-Use Property with Garage
Mixed-Use Property with Garage

23 Tubac Rd, Tubac, AZ 85646

$499,000
4,254 sqft

A retail area and separate residence provide distinct commercial and living spaces within one building.

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Commercial Land Parcel
Commercial Land Parcel

1127 Circulo Mercado, Rio Rico, AZ 85648

$70,000
0.18 AC lot

Commercial-zoned parcel within the Rio Rico Unit 7 subdivision.

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Commercial Land Along Main Road
Commercial Land Along Main Road

2385 N Grand Ave, Nogales, AZ 85621

$320,000
4,520 sqft

Commercial zoning and convenient road access are noted for this one-acre parcel.

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Rectangular Agricultural Parcel
Rectangular Agricultural Parcel

4 Lower Elgin Road, Elgin, AZ 85611

$499,900
35.09 AC lot

Corner property with a private well and barbed-wire fencing.

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Santa Cruz County, AZ Commercial Real Estate Market Trends and Statistics

Explore 72 commercial real estate for sale in Santa Cruz County, AZ, showcased through 67 active listings on our real estate platform. These investment opportunities span a total of 773,132 square feet of properties for sale, with an estimated market value of $59,084,070.

Sale prices for business properties in Santa Cruz County, AZ start at $48,000, averaging $1,074,255, and reaching up to $6,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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