Add Listing
    For Lease
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Space Uses
    • Retail
    • Restaurant
    • Office
    • Coworking
    • Medical Space
    • Automotive
    • Industrial
    • Warehouse
    • Flex
    • Hospitality
    • Sports & Entertainment
    • Specialty
    Price
    Price range
    $
    $
    Size
    Property size / sq.ft.
    AI Search

    Ladys Island, SC Commercial Real Estate for Lease

    Notify Me
    List
    Map
    New Custom-Built Office Suites
    $1,500 / Mo
    3,049 SF

    New Custom-Built Office Suites

    101 Ladys Island Cmns, Ladys Island, SC 29907

    Pre-leasing custom office suites with private entrances, available Q2 2026.

    • Pre‑leasing now for Q2 2026 occupancy.
    • Custom‑built, two‑story office building by Phifer Construction.
    • Suites feature exterior windows and private entrances.
    • ADA compliant design.
    • Custom layouts available if secured during construction.
    Updated: Dec 9, 2025
    View details
    Renovated Office Space For Rent
    $1,600 / Mo

    Renovated Office Space For Rent

    1 Merchants Ln, Ladys Island, SC 29907

    Newly renovated 650 SF office space with utilities included.

    • Newly renovated suite with new flooring and fresh paint.
    • Excellent visibility off Sam's Point Road with high vehicle traffic.
    • Prominent signage exposure.
    • Utilities (water, sewer, and electricity) included in the monthly rent.
    • Located in the Newpoint Corner commercial buildings.
    Updated: Feb 26
    View details
    Based on your search, we've compiled 8 Potential Opportunities for your consideration. Besides 2 Active listings in Ladys Island, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 2 Properties for Sales.

    Explore Commercial real estate for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    High-Traffic Commercial Land For Rent
    Pending
    $5,000 / Mo
    33,541 SF

    High-Traffic Commercial Land For Rent

    Commercial land in high-traffic Beaufort location, suitable for various uses.

    91 Sea Island Pkwy, Beaufort, SC 29907
    View details
    Sea Island Parkway Office Space
    $22 SF/Yr
    1,250 SF

    Sea Island Parkway Office Space

    Prime Office, 1250 sq ft, Lady's Island

    189 Sea Island Pkwy, Beaufort, SC 29907
    View details
    New Office Building in Port Royal
    $750 / Mo
    44,431 SF

    New Office Building in Port Royal

    Centrally located office spaces with shared amenities and ample parking.

    1319 Ladys Island Dr, Port Royal, SC 29935
    View details
    Prime Commercial Site in Port Royal
    $6,000 / Mo
    43,996 SF

    Prime Commercial Site in Port Royal

    High-visibility commercial site ideal for retail, professional, and food businesses.

    1670 Ribaut Rd, Port Royal, SC 29935
    View details

    Explore Similar Spaces for Sale in Ladys Island, SC

    Consider Similar Space for Sale. We found 2 Spaces in Nearby Locations matching your search parameters.

    Lady's Island Commercial Site
    Pending
    $499,000
    1.30 Acres

    Lady's Island Commercial Site

    High-traffic commercial land in Lady's Island Village Center.

    Hazel Farm Rd, Ladys Island, SC 29907
    View details
    Lady's Island Commercial Site
    Pending
    $499,000
    1.39 Acres

    Lady's Island Commercial Site

    High-traffic commercial land in Lady's Island Village Center.

    Fry Rd, Ladys Island, SC 29907
    View details

    Ladys Island, SC Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Ladys Island, SC with 4 listings featured on our commercial real estate exchange. The current inventory includes 132,823,150 square feet of properties with an estimated lease value of $5 SF/Yr.

    Estimated lease rates for Commercial real estate in Ladys Island, SC begin at $5 SF/Yr, with an average of $5 SF/Yr and extend to $5 SF/Yr.
    List
    Map

    Browse Commercial real estate for Lease Near Ladys Island, SC

    Popular Searches in Ladys Island, SC

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!