Daniel Island, SC Commercial Real Estate for Lease

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Wando, SC Mount Pleasant, SC North Charleston, SC Hanahan, SC Goose Creek, SC Isle Of Palms, SC Awendaw, SC Sullivans Island, SC

341 properties

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Retail and Medical Office Space

State Rd S-8-33, Charleston, SC 29492

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Retail and medical office space at Point Hope community.

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Commercial Space for Lease

463 King St, Charleston, SC 29403

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Commercial space available for lease in Charleston, SC.

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Class A Office Space

40 Calhoun St, Charleston, SC 29401

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Walkable campus with office and service-related businesses.

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Office Space For Lease

177 Meeting St, Charleston, SC 29401

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Office space available for lease.

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Office Space Available For Lease

656 Ellis Oak Ave, Charleston, SC 29412

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Office space available for lease in Charleston, SC.

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Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center

Based on your search, we've compiled 480 Potential Opportunities for your consideration. Besides 341 Active listings in Daniel Island, SC, we suggest exploring alternatives. Consider Similar 135 Spaces for Sales.

Commercial real estate for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Strip Mall Retail Shops

280 West Coleman Boulevard & 976 Houston Northcutt Boulevard, Mount Pleasant, SC 29464

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4,602 sqft

Busy boutique shopping center offering 35 small retail shop spaces.

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Renovated Heavy Industrial Flex Space

2532 Spruill Ave, North Charleston, SC 29405

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27,840 sqft

Fully renovated warehouse with three loading docks, three drive-in doors, 6-inch concrete slab, and three-phase power.

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Warehouse With Drive-Through Doors

2102 Spruill Ave, North Charleston, SC 29405

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4,200 sqft

Heavy Industrial zoning, office space, garage space, and three-phase power support a range of warehouse operations.

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Second-Floor Office Suite

242 Mathis Ferry Road # 201, Mount Pleasant, SC 29464

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Professional office suite with private rooms, collaborative workspace, break area, storage, and adjacent common restrooms.

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Similar Spaces for Sale in Daniel Island, SC

Consider Similar Space for Sale. We found 135 Spaces matching your search parameters.

Freestanding Flex Building

235 Huger St, Charleston, SC 29403

$850,000

1,400 sqft

Two-level commercial layout combines office space with climate-controlled storage and workspace.

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Day Care Center with Office Potential

1910 McMillan Avenue North, Charleston, SC 29405

$2,300,000

12,895 sqft

Former childcare facility with adaptability for medical, professional, religious, or financial service operations.

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Two-Story Medical Office Space

1845 Savage Rd, Charleston, SC 29407

$1,300,000

3,383 sqft

Standalone clinical facility with a durable exterior and an existing medical layout.

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Historic Bed & Breakfast with Carriage House

201 Ashley Avenue, Charleston, SC 29403

$5,650,000

4,468 sqft 0.16 AC lot

Restored lodging property with eight guest accommodations, rare onsite parking, and a separate active short-term rental.

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Three-Story Mixed-Use Property

651 King Street, Charleston, SC 29403

$4,695,000

4,253 sqft 0.05 AC lot

Modern Charleston asset combining short-term lodging with leased commercial space and restaurant-ready infrastructure.

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Townhouse-Style Condominium with Elevator

18 Boyces Wharf, Charleston, SC 29401

$5,450,000

3,363 sqft

Three-story masonry condominium features a private elevator, full-width terrace access, renovated kitchen, and a three-car garage.

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T-Head Marina Slip

33 Lockwood Drive #Slip Lu206, Charleston, SC 29401

$150,000

139,392 sqft

Berth includes dual-voltage electrical service, dedicated water, Wi-Fi, fuel access, and pump-out facilities.

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Historic Boutique Inn with Carriage House

201 Ashley Avenue, Charleston, SC 29403

$5,650,000

4,468 sqft

Turnkey historic hospitality property with eight accommodations, including a legal short-term rental carriage house and onsite parking.

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Dry Storage Warehouse on Fenced Lot

1795 King Street Ext, Charleston, SC 29405

$3,900,000

20,000 sqft 1.00 AC lot

±120,000 SF dry storage warehouse on a ±1-acre partially fenced lot with access from two sides.

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Three-Story Mixed-Use Property

651 King St, Charleston, SC 29403

$4,695,000

4,253 sqft

2024 construction pairs a leased commercial storefront with a five-bedroom short-term rental and rooftop terrace.

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Mixed-Use Property with Restaurant Shell

69 Columbus Street, Charleston, SC 29403

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4,328 sqft

Four-space mixed-use property combining barber, restaurant, and residential components.

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Turn-Key Wedding Venue Space

207 Rutledge Ave, Charleston, SC 29403

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3,149 sqft

Ground-floor commercial space includes FF&E and an existing lease through fall 2026.

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Renovated Mixed-Use Building

21 Broad Street, Charleston, SC 29401

$4,141,000

4,254 sqft

Historic Charleston property combines office space with two residential rental components.

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Restaurant Site with 7-Story Height

1953 Savannah Highway, Charleston, SC 29407

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5,474 sqft 1.60 AC lot

Freestanding restaurant on 1.6 acres with overlay approval for up to seven stories at this key interchange setting.

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Multi-Tenant Light Industrial Property

339 Fleming Road, Charleston, SC 29412

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11,783 sqft 1.72 AC lot

Three fully conditioned light industrial buildings with eight roll-up doors and secure gated access, plus 45+ boat/RV parking spaces.

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Vacant Bank Branch

2275 Ashley Crossing Drive, Charleston, SC 29414

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3,641 sqft

Commercial banking facility with dedicated on-site parking and a substantial land component.

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Freestanding Retail or Office Building

936 Savannah Highway, Charleston, SC 29407

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960 sqft

Vacant freestanding building with a private front parking lot and large signage along Savannah Highway.

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Historic Mixed-Use Building

49 Archdale St, Charleston, SC 29401

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5,500 sqft

Existing offices, rooftop terrace, parking, and preserved architectural elements support a flexible commercial configuration.

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Approved Mixed-Use Development Land

645 East Bay Street, Charleston, SC 29403

$1,295,000

0.11 AC lot

Approved plans support a mixed-use project with professional office, residential condominiums, and covered parking improvements.

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