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    Daniel Island, SC Commercial Real Estate for Sale

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    Wando, SC Mount Pleasant, SC Hanahan, SC
    115 listings
    Historic Charleston Mixed-Use Building
    $2,650,000
    4,923 SF
    Historic Charleston Mixed-Use Building

    59 Broad Street, Charleston, SC 29401

    Three-story mixed-use building in Charleston's historic commercial corridor.
    • Prime location on Broad Street in Charleston's historic commercial corridor
    • Approved entitlements for food & beverage use
    • Permit‑ready storefront renovation with accordion doors and updated facade
    • Approved addition of an 820 sq ft fourth‑floor penthouse
    • Mixed‑use building offering flexibility for owner‑occupancy or investment
    Updated: Mar 31
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    Updated Historic 2-Bedroom Home
    $460,000
    993 SF
    Updated Historic 2-Bedroom Home

    20 Amherst Street, Charleston, SC 29403

    A character-rich 2-bedroom home with 9-foot ceilings, hardwood floors, and recent HVAC, roof, and water-heater upgrades.
    • 2‑bedroom, 1‑bath Charleston home built in 1852 with high ceilings and an eat‑in kitchen
    • Renovated bathroom in 2024; new HVAC and ductwork in 2025
    • Brand new hot water heater installed in 2026
    • Freshly resealed and painted metal roof; public water and public sewer connected
    • Hardwood floors and a classic decorative fireplace, plus Charleston‑style side porches
    Updated: May 28
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    Charleston Land Package For Sale
    $3,500,000
    0.36 Acres
    Charleston Land Package For Sale

    Two adjoining lots totaling approximately .36 acres in Charleston, SC.

    148 President Street, Charleston, SC 29403

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    Retail Redevelopment Opportunity
    $825,000
    7,029 SF
    Retail Redevelopment Opportunity

    Opportunity Zone property with a 7,029 SF retail building and additional residential lot, offering flexible redevelopment potential.

    1831 Reynolds Ave, 1824 & 1828 Dayton Street, Charleston, SC 29405

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    Charleston Medical Property Investment
    $1,895,000
    5,567 SF
    Charleston Medical Property Investment

    Thriving medical property in Charleston, SC with favorable lease terms.

    2039 Savannah Highway, Charleston, SC 29407

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    Warehouse Office with Drive-In Access
    $625,000
    2,520 SF
    Warehouse Office with Drive-In Access

    Small warehouse-office set up for light industrial or service use, featuring drive-in and dock-high loading with on-site restroom.

    806 Elsey Dr, Charleston, SC 29407

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    Charleston Land Mixed-Use Opportunity
    $1,050,000
    0.13 Acres
    Charleston Land Mixed-Use Opportunity

    Vacant parcel on King St, ideal for mixed-use development.

    975 King Street, Charleston, SC 29403

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    Prime West Ashley Acreage Opportunity
    $999,000
    2.37 Acres
    Prime West Ashley Acreage Opportunity

    2.37 acres in West Ashley, ideal for development.

    736 Savage Road, Charleston, SC 29414

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    Daniel Island Deepwater Residential Opportunity
    $5,500,000
    1.66 Acres
    Daniel Island Deepwater Residential Opportunity

    Rare waterfront acreage ideal for residential or commercial development.

    1995 Daniel Island Drive, Charleston, SC 29492

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    Redevelopment Service Garage Site
    $4,200,000
    9,516 SF
    Redevelopment Service Garage Site

    A General Business-zoned opportunity zone parcel with an on-site service garage and utilities ready for redevelopment.

    1822 Meeting Street Road, Charleston, SC 29405

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    Flex Building with Roll-Up Doors
    $3,200,000
    8,000 SF
    Flex Building with Roll-Up Doors

    Renovated flex building on a cleared lot with high ceilings, brick accents, and 40 parking spaces.

    2910 Rivers Avenue, Charleston, SC 29405

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    Free-Standing Office Building
    $895,000
    5,000 SF
    Free-Standing Office Building

    A flexible office layout offers private offices, open bullpen space, and exam-ready rooms for medical or legal use.

    4476 Leeds Place West, Charleston, SC 29405

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    Charleston Multifamily Bed and Breakfast
    $3,197,000
    6,025 SF
    Charleston Multifamily Bed and Breakfast

    Five-unit bed and breakfast in Charleston's Short-Term Rental Overlay.

    194-196 Rutledge Avenue, Charleston, SC 29403

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    Downtown Charleston Corner Lot Restaurant
    $3,250,000
    2,300 SF
    Downtown Charleston Corner Lot Restaurant

    High-profile corner lot with renovated restaurant in downtown Charleston.

    211 Rutledge Ave, Charleston, SC 29403

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    Retail/Office Center Near I-526
    $4,100,000
    5,250 SF
    Retail/Office Center Near I-526

    Two-story retail/office center in Cainhoy commercial district.

    2030 Wambaw Crk, Charleston, SC

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    Freestanding Office Building Corner
    $1,195,000
    2,038 SF
    Freestanding Office Building Corner

    Former bank with a proven layout, strong visibility, and access in a dense business corridor of medical and retail uses.

    9205 University Blvd, Charleston, SC 29406

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    Office-Retail Condo Opportunity
    $850,000
    1,655 SF
    Office-Retail Condo Opportunity

    Two condo suites with storefront windows offer strong visibility and flexible owner-occupant potential in a town center setting.

    234 Seven Farms Drive, Charleston, SC 29492

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    Freestanding Mixed-Use Building
    $1,050,000
    1,120 SF
    Freestanding Mixed-Use Building

    Two-story mixed-use property with an income-producing café below and an occupied apartment above.

    109 President Street, Charleston, SC 29403

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    Charleston Warehouse/Storage Facility For Sale
    $3,900,000
    20,000 SF
    Charleston Warehouse/Storage Facility For Sale

    20,000 SF warehouse/storage facility in Charleston's upper peninsula.

    1795 King Street Ext, Charleston, SC 29405

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    Corner Retail Office Suite
    $990,000
    1,120 SF
    Corner Retail Office Suite

    Ground-floor corner unit with floor-to-ceiling glass and dual street access, suited for office, retail, or service use.

    210 Coming Street, Unit C, Charleston, SC 29403

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    Freestanding Mixed-Use Retail/Office
    $500,000
    1,330 SF
    Freestanding Mixed-Use Retail/Office

    Freestanding two-story building with flexible office, medical office, or retail use.

    154 Cannon Street, Charleston, SC 29403

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    Turn-Key Restaurant in Historic District
    $3,650,000
    2,890 SF
    Turn-Key Restaurant in Historic District

    Restaurant opportunity in downtown Charleston's historic district.

    5 Cumberland St, Charleston, SC 29401

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    Freestanding Retail or Office Building
    $2,050,000
    Freestanding Retail or Office Building

    Conditioned shell space in a downtown Charleston freestanding building, ready for upfit with convenient parking and prominent signage.

    1084 King St, Charleston, SC 29403

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    High-Visibility Mixed-Use Land
    $7,300,000
    0.55 Acres
    High-Visibility Mixed-Use Land

    Five-parcel site zoned General Business with overlay approvals for accommodations and short-term rentals, highly visible from a major corridor.

    657 King Street, Charleston, SC 29403

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    Daniel Island, SC Commercial Real Estate Investment Opportunities Market Analysis

    Explore 115 commercial real estate for sale in Daniel Island, SC, showcased through 115 active listings on our real estate platform. These investment opportunities span a total of 488,866 square feet of properties for sale, with an estimated market value of $219,671,200.

    Sale prices for business properties in Daniel Island, SC start at $320,000, averaging $3,723,240, and reaching up to $24,025,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Demographics Overview

    Population 20K
    Population Growth (5Y) +49.6%
    Median Household Income $115,605
    College Educated 91.8%

    High-Yield Neighborhoods for Investment

    Identify Daniel Island submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    Charleston - 29492 $497K

    Listings Trend

    New vs delisted commercial listings in Charleston County

    New Delisted

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    Most Searched ZIP Codes in Daniel Island, SC

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    • 29414
    • 29407
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    • 29401
    • 29492
    • 29412
    • 29406
    • 29418
    • 29420
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