Charleston, SC Commercial Real Estate for Lease

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225 properties
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Freestanding Office Building For Lease
Freestanding Office Building For Lease

4360 Corporate Rd N, Charleston, SC 29405

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33,475 sqft 2.40 AC lot

33,475 SF office building with superior access to amenities.

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Charleston Commercial Land Ground Lease
Charleston Commercial Land Ground Lease

890 Folly Rd, Charleston, SC

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0.65 AC lot

±1.65 acre commercial land for ground lease in Charleston.

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Retail Space on King Street
Retail Space on King Street

354 King St, First Floor Retail Space, Charleston, SC 29401

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First floor retail space available for rent in Charleston.

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Charleston Retail Property For Rent
Charleston Retail Property For Rent

2245 Ashley Crossing Dr, Charleston, SC

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15,074 sqft 19.86 AC lot

Retail property in Charleston County with high residential growth.

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Third-Floor Office Suite
Third-Floor Office Suite

149 E Bay St, Charleston, SC 29401

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2,375 sqft

Third-floor office suite in a historic building with elevator access, natural light, and suite signage.

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Office Complex Near Citadel Mall
Office Complex Near Citadel Mall

1 S Park Cir, Charleston, SC 29407

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3,843 sqft 10.82 AC lot

Three-building office complex on 10.82 acres with ample parking.

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Office Suite Off I-526
Office Suite Off I-526

4105 Faber Pl Dr N, Charleston, SC 29405

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3,442 sqft

Flexible office suite options in a Class A+ building with high-quality finishes and on-site parking.

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Class A+ Office Space Available
Class A+ Office Space Available

4105 Faber Pl Dr N, Charleston, SC

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3,017 sqft 5.08 AC lot

Modern office building with flexible layouts and ample parking.

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Based on your search, we've compiled 320 Potential Opportunities for your consideration. Besides 225 Active listings in Charleston, SC, we suggest exploring alternatives. Consider Similar 91 Spaces for Sales.

Commercial real estate for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Medical Office Space with Clinical Upfit
Medical Office Space with Clinical Upfit

2320 Cosgrove Avenue, North Charleston, SC 29405

$24 SF/Yr
4,935 sqft 0.31 AC lot

Plumbing and medical connections remain throughout the building, alongside on-site parking.

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Move-In Ready Office Suite with Parking
Move-In Ready Office Suite with Parking

3900 Leeds Avenue, North Charleston, SC 29405

$22 SF/Yr
2,250 sqft

Turnkey office suite with flexible layout, strong visibility, and abundant parking in North Charleston.

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Class A Office Space
Class A Office Space

4390 Belle Oaks Drive, North Charleston, SC 29405

$27 SF/Yr
88,505 sqft

Class A office building with convenient highway access.

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Flex Unit For Rent
Flex Unit For Rent

2894 Pringle St, North Charleston, SC 29405

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1,000 sqft 0.25 AC lot

Flex unit with warehouse and office space available for rent.

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Similar Spaces for Sale in Charleston, SC

Consider Similar Space for Sale. We found 91 Spaces matching your search parameters.

Mixed-Use Office Property
Mixed-Use Office Property

565 Savannah Highway, Charleston, SC 29407

$1,620,000
3,018 sqft

Flexible ground-floor layout with kitchen and mixed-use zoning for business and residential uses.

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Historic Bed & Breakfast with Carriage House
Historic Bed & Breakfast with Carriage House

201 Ashley Avenue, Charleston, SC 29403

$5,300,000
4,468 sqft 0.16 AC lot

Restored lodging property with eight guest accommodations, rare onsite parking, and a separate active short-term rental.

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Three-Story Mixed-Use Property
Three-Story Mixed-Use Property

651 King Street, Charleston, SC 29403

$4,695,000
4,253 sqft 0.05 AC lot

Modern Charleston asset combining short-term lodging with leased commercial space and restaurant-ready infrastructure.

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Historic Mixed-Use Mansion
Historic Mixed-Use Mansion

20 S Battery Street, Charleston, SC 29401

$16,500,000
15,699 sqft

Renovated Greek Revival property combining a private residence with an 11-room licensed inn.

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Townhouse-Style Condominium with Elevator
Townhouse-Style Condominium with Elevator

18 Boyces Wharf, Charleston, SC 29401

$5,450,000
3,363 sqft

Three-story masonry condominium features a private elevator, full-width terrace access, renovated kitchen, and a three-car garage.

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Downtown Commercial Land
Downtown Commercial Land

38 Amherst Street, Charleston, SC 29403

$800,000
4,792 sqft

Vacant commercial land suited for future development in a historic downtown setting.

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Historic Two-Unit Duplex
Historic Two-Unit Duplex

96 Bogard St, Charleston, SC 29403

$900,000
2,068 sqft

Flexible duplex with separate residences, historic detailing, porches, fenced outdoor space, and off-street parking.

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Historic Boutique Inn with Carriage House
Historic Boutique Inn with Carriage House

201 Ashley Avenue, Charleston, SC 29403

$5,300,000
4,468 sqft

Turnkey historic hospitality property with eight accommodations, including a legal short-term rental carriage house and onsite parking.

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New Corner Mixed-Use Investment Property
New Corner Mixed-Use Investment Property

651 King Street, Charleston, SC 29403

$4,695,000
4,253 sqft

Newly built three-story mixed-use property with NNN ground-floor retail and an operational short-term rental on upper floors.

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Dry Storage Warehouse on Fenced Lot
Dry Storage Warehouse on Fenced Lot

1795 King Street Ext, Charleston, SC 29405

$3,900,000
20,000 sqft 1.00 AC lot

±120,000 SF dry storage warehouse on a ±1-acre partially fenced lot with access from two sides.

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Mixed-Use Property with Restaurant Shell
Mixed-Use Property with Restaurant Shell

69 Columbus Street, Charleston, SC 29403

Contact for pricing
4,328 sqft

Four-space mixed-use property combining barber, restaurant, and residential components.

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Three-Story Mixed-Use Property
Three-Story Mixed-Use Property

651 King St, Charleston, SC 29403

$4,695,000
4,253 sqft

2024 construction pairs a leased commercial storefront with a five-bedroom short-term rental and rooftop terrace.

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T-Head Marina Slip
T-Head Marina Slip

33 Lockwood Drive #Slip Lu206, Charleston, SC 29401

$150,000
139,392 sqft

Berth includes dual-voltage electrical service, dedicated water, Wi-Fi, fuel access, and pump-out facilities.

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Office Building with Abundant Natural Light
Office Building with Abundant Natural Light

1524 Ashley River Rd, Charleston, SC 29407

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5,452 sqft

Adaptable office layout with efficient floor plates and ample parking for staff and clients.

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Turn-Key Wedding Venue Space
Turn-Key Wedding Venue Space

207 Rutledge Ave, Charleston, SC 29403

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3,149 sqft

Ground-floor commercial space includes FF&E and an existing lease through fall 2026.

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Freestanding Flex Building
Freestanding Flex Building

235 Huger Street, Charleston, SC 29403

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1,400 sqft

Two-level commercial layout combines office space with climate-controlled storage and workspace.

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