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    Durham, NC Commercial Real Estate for Lease

    116 results
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    Office Space Near Universities
    $1,995 / Mo
    1,000 SF

    Office Space Near Universities

    1804 Martin Luther King Junior Pkwy, Durham, NC 27707

    Office space in Durham, close to amenities and universities.

    • Prime location near shopping centers and residential complexes.
    • Walking distance to restaurants, grocery stores, cinemas, and banks.
    • Close proximity to Duke University (3 miles).
    • Convenient access to Research Triangle Park (8 miles).
    • Easy access to Raleigh‑Durham International Airport (15 miles).
    Updated: Nov 25, 2025
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    Prime Durham Office Space Available
    $29,460
    22,649 SF

    Prime Durham Office Space Available

    5310 S Alston Ave, Durham, NC 27713

    12,000 SF office space for lease in Durham, NC.

    • Prime Location: At the edge of Research Triangle Park (RTP) in Durham's economic hub, offering direct connectivity.
    • Flexible Office Space: Features 12,000 square feet of traditional office space with a flexible open floor plan.
    • Strategic Location Advantages: Easy access to major transportation arteries.
    • Versatile Zoning: Zoned 01.2 (Office Institutional), providing versatility for various professional uses.
    • Modern Design & Natural Light: Contemporary design with abundant natural light.
    Updated: Nov 19, 2025
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    Durham Office Space For Lease
    $45,045
    2,145 SF

    Durham Office Space For Lease

    Flexible office unit with ample parking and recent upgrades.

    1906 A, Durham, NC 27713
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    Retail Space Near RTP
    $3,232 / Mo
    1,168 SF

    Retail Space Near RTP

    Retail space in a vibrant neighborhood center near RTP.

    5125 Nc-55, Durham, NC 27713
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    Prime Medical Office Space Available
    Pending
    $18 SF/Yr
    2,312 SF

    Prime Medical Office Space Available

    Versatile medical/office space in Durham's thriving North Duke corridor.

    2609 N Duke St Unit Bldg 300, Durham, NC 27704
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    Office Suite with Private Offices
    $36,000
    1,760 SF

    Office Suite with Private Offices

    Office suite featuring multiple private office spaces for rent.

    5315 Highgate Dr, Durham, NC 27713
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    Office Condo in Durham's Office Park
    $3,500 / Mo
    2,000 SF

    Office Condo in Durham's Office Park

    Office condominium with private entrance in a convenient location.

    6 Consultant Pl, Durham, NC 27707
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    Auburn Square End Unit
    $1,850 / Mo

    Auburn Square End Unit

    3BR, 2BTH end unit near Duke, UNC, RTP, Southpoint.

    960 Cinnamon Dr, Durham, NC 27713
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    Charming Townhome in Woodcroft
    $1,950 / Mo

    Charming Townhome in Woodcroft

    3BR/2.5BA end-unit townhome in Durham's desirable Woodcroft neighborhood.

    7 Preakness Dr, Durham, NC 27713
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    Durham Duplex Near Duke
    $1,095 / Mo
    512 SF

    Durham Duplex Near Duke

    One-bedroom duplex unit with included appliances, convenient location in Durham.

    408 N Guthrie Ave, Durham, NC 27703
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    Sprawling Townhome in Stellar Durham
    $2,250 / Mo
    1,890 SF

    Sprawling Townhome in Stellar Durham

    Light-filled townhome with high-end finishes, chef's kitchen, and private backyard.

    118 Brookview St, Durham, NC 27713
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    Sprawling Townhome in Stellar Durham
    $2,250 / Mo
    1,890 SF

    Sprawling Townhome in Stellar Durham

    Light-filled townhome with high-end finishes, chef's kitchen, and private backyard.

    118 Brookview St, Durham, NC 27713
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    Durham Townhome with Back Deck
    $1,500 / Mo
    1,501 SF

    Durham Townhome with Back Deck

    Well-maintained townhome in South Durham with modern updates and convenient location.

    11 Edgebrook Cir, Durham, NC 27703
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    Carr Rd Apartments For Rent
    $540 / Mo

    Carr Rd Apartments For Rent

    Apartment building available for rent in Durham, North Carolina.

    3432 Carr Rd, Durham, NC 27703
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    Downtown Durham Retail/Office Space
    Contact for pricing
    8,400 SF

    Downtown Durham Retail/Office Space

    Prime Durham location, two suites available

    706 9Th St, Durham, NC 27705
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    Durham Retail Space: 13,802 SF
    $24 SF/Yr
    13,802 SF

    Durham Retail Space: 13,802 SF

    Sublease opportunity: Prime Research Triangle location.

    4025 Stirrup Creek Dr, Durham, NC 27703
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    2927 Holloway St
    $10 SF/Yr
    8,415 SF

    2927 Holloway St

    Retail properties • 8,415 SF

    2927 Holloway St, Durham, NC 27703
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    Durham Retail Space: Prime Location
    $25 SF/Yr
    6,600 SF

    Durham Retail Space: Prime Location

    6,600 SF Retail; Two Suites Available

    2100 Miami Blvd, Durham, NC 27703
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    Winchester Place Office Space Durham NC
    $29 SF/Yr
    111,689 SF

    Winchester Place Office Space Durham NC

    Durham Office Building: Prime Research Triangle Location

    4309 Emperor Blvd, Durham, NC 27703
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    Westside Bottling: Prime Retail Space
    Contact for pricing
    71,652 SF

    Westside Bottling: Prime Retail Space

    Durham retail center: high-traffic, flexible space.

    3214 Hillsborough Rd, Durham, NC 27705
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    311 Liggett St
    $384 / Mo
    5,729 SF

    311 Liggett St

    Retail properties • 5,729 SF

    311 Liggett St, Durham, NC 27701
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    Welcome Venture Park: Durham, NC
    Contact for pricing
    392,000 SF

    Welcome Venture Park: Durham, NC

    Large Industrial/Office Space Available

    1539 Hamlin Rd, Durham, NC 27704
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    Prime Durham Executive Office Space
    $29 SF/Yr
    81,145 SF

    Prime Durham Executive Office Space

    Modern Durham office suites, 18K-27K SF available

    4307 Emperor Blvd, Durham, NC 27703
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    Patterson Place Power Center
    $26 SF/Yr
    160,942 SF

    Patterson Place Power Center

    Durham Retail Space Available Now

    3616 Witherspoon Blvd, Durham, NC 27707
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    Durham, NC Commercial Real Estate Leasing Opportunities Market Analysis

    Explore Commercial Real Estate leasing options in Durham, NC with 166 listings featured on our commercial real estate exchange. The current inventory includes 111,184,417,080 square feet of properties with an estimated lease value of $40,645.

    Estimated lease rates for Commercial Real Estate in Durham, NC begin at $3 SF/Yr, with an average of $713 /Mo and extend to $36,000.

    In Durham, NC, current lease rates show:

    • Office Properties & Spaces positioned at $1,184
    • Retail properties measuring $178
    • Office space assessed at $2,269
    • Other office properties calculated at $26
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    Browse Commercial real estate for Lease Near Durham, NC

    Popular Searches in Durham, NC

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    Most Searched ZIP Codes in Durham, NC

    • 27703
    • 27713
    • 27707
    • 27701
    • 27705
    • 27704
    • 27712
    • 27709

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