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    St Charles County, MO Commercial Real Estate for Lease

    289 results
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    Move-in Ready Office Suites Available
    Pending
    $570 / Mo
    63,598 SF

    Move-in Ready Office Suites Available

    1480 Woodstone Dr, Saint Charles, MO 63304

    Updated office suites with included utilities and amenities for rent.

    • All‑inclusive rent: Heat, electricity, trash, Wi‑Fi, kitchenette, and conference room use included.
    • Move‑in ready with new carpet, paint, and lighting.
    • Convenient location with ample parking and easy access to Hwy 364 and 94.
    • Opportunity to combine multiple suites (217, 218, 219) for a larger contiguous space (848 SF).
    • Updated interior and exterior renovations.
    Updated: Jan 13
    View details
    O'Fallon Retail Space Available
    $1,438 / Mo

    O'Fallon Retail Space Available

    806 Runny Meade Est, O Fallon, MO 63366

    1,150 SF retail space with highway visibility in O'Fallon.

    • Highway 70 Visibility
    • High Traffic Location
    • Open Floor Plan
    • Densely Populated Residential Area Near Industrial Park
    • Suitable for Laundromat, Restaurant, or Insurance Office
    Updated: Nov 26, 2025
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    Move-In Ready Office Space
    $4,500 / Mo
    40,511 SF

    Move-In Ready Office Space

    3,000 SF office space with high-end build out.

    1048 Rondale Ct, Dardenne Prairie, MO 63368
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    Move-in Ready Office in St Charles
    $500 / Mo

    Move-in Ready Office in St Charles

    Full service office space with modern amenities and convenient location.

    1480 Woodstone Dr, Saint Charles, MO 63304
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    Remodeled Office Space Near I-70
    $1,750 / Mo
    1,064 SF

    Remodeled Office Space Near I-70

    Recently remodeled office suites for lease near I-70 in St. Charles.

    1600 Boones Lick Rd, Saint Charles, MO 63301
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    Remodeled Office Space For Rent
    $950 / Mo
    520 SF

    Remodeled Office Space For Rent

    Recently remodeled office space for lease near I-70 in St. Charles.

    1600 Boones Lick Rd, Saint Charles, MO 63301
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    Office Space on Jungermann Road
    $585 / Mo
    3,850 SF

    Office Space on Jungermann Road

    Office space with high traffic, ideal for various professionals.

    60 Gailwood Dr, St Peters, MO 63376
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    Retail Space in St Charles
    $800 / Mo

    Retail Space in St Charles

    Retail space available for lease in St Charles, MO.

    1055 1 Capital, Saint Charles, MO 63301
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    Move-in Ready Office Suite
    $840 / Mo
    63,598 SF

    Move-in Ready Office Suite

    Office suite with included utilities and amenities in St Charles.

    1480 Woodstone Dr, Saint Charles, MO 63304
    View details
    Move-in Ready Office Space
    $500 / Mo

    Move-in Ready Office Space

    Full service office space with modern amenities included in rent.

    1480 Woodstone Dr, Saint Charles, MO 63304
    View details
    Move-in Ready Office Space
    $1,070 / Mo

    Move-in Ready Office Space

    Updated office space with utilities included near Hwy 364.

    1480 Woodstone Dr, Saint Charles, MO 63304
    View details
    Remodeled Office Space Near I-70
    $900 / Mo
    449 SF

    Remodeled Office Space Near I-70

    Recently remodeled office suites for lease near I-70 in St. Charles.

    1600 Boones Lick Rd, Saint Charles, MO 63301
    View details
    O'Fallon Condo with Balcony
    $1,500 / Mo

    O'Fallon Condo with Balcony

    Two-bedroom, two-bath condo with balcony in O'Fallon, Missouri.

    333 Bramblett Hl, O Fallon, MO 63366
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    Prime St. Charles Retail Space
    Contact for pricing
    3,119 SF

    Prime St. Charles Retail Space

    3,119 SF Retail Building - Available Now

    1920 Zumbehl Rd, Saint Charles, MO 63303
    View details
    Crafton Drive Industrial Warehouse
    $12 SF/Yr
    4,750 SF

    Crafton Drive Industrial Warehouse

    Modern O'Fallon, MO warehouse space for lease.

    102-212 Crafton Dr, O'Fallon, MO 63366
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    O'Fallon Retail Space For Lease
    Contact for pricing
    1,400 SF

    O'Fallon Retail Space For Lease

    1,400 SF Retail Space in O'Fallon, MO

    3029 State Hwy, O'Fallon, MO 63368
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    St. Charles County Distribution Center
    Contact for pricing
    811,300 SF

    St. Charles County Distribution Center

    Class A Distribution Space Available in Missouri

    5000 Premier Pkwy, Saint Charles, MO 63301
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    Waterbury Plaza: O'Fallon Office Space
    $17 SF/Yr
    45,879 SF

    Waterbury Plaza: O'Fallon Office Space

    Prime O'Fallon, MO office space available.

    929 Waterbury Falls Dr, O'Fallon, MO 63368
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    2209 State Hwy
    Contact for pricing
    157,934 SF

    2209 State Hwy

    Lifestyle centers • 157,934 SF

    2209 State Hwy, O'Fallon, MO 63368
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    O'Fallon Retail Space For Lease
    Contact for pricing
    1,200 SF

    O'Fallon Retail Space For Lease

    1,200 sq ft retail space in O'Fallon, MO

    0 Ofallon Ave, O'Fallon, MO 63366
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    St. Peters Medical Office Space
    $10 SF/Yr
    15,000 SF

    St. Peters Medical Office Space

    1,980 SF Medical Office for Lease

    104 Hospital Dr, St. Peters, MO 63376
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    Frontier Plaza: O'Fallon Retail Space
    Contact for pricing
    5,100 SF

    Frontier Plaza: O'Fallon Retail Space

    Prime O'Fallon retail space available.

    2011 State Hwy, O'Fallon, MO 63366
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    St. Peters Office/Warehouse Space
    $10 SF/Yr
    4,910 SF

    St. Peters Office/Warehouse Space

    Modern 4,910 SF Office & Warehouse

    4012 Service Rd, St. Peters, MO 63376
    View details
    Wentzville Flex Space Available
    $15 SF/Yr
    20,850 SF

    Wentzville Flex Space Available

    Modern Flex Space, 1,519 SF Available

    135 Hamilton Industrial Ct, Wentzville, MO 63385
    View details

    St Charles County, MO Commercial Real Estate Leasing Opportunities Market Analysis

    Explore Commercial Real Estate leasing options in St Charles County, MO with 349 listings featured on our commercial real estate exchange. The current inventory includes 73,378,989,322 square feet of properties with an estimated lease value of $2,485 /Mo.

    Estimated lease rates for Commercial Real Estate in St Charles County, MO begin at $1.33 SF/Yr, with an average of $19 SF/Yr and extend to $270 SF/Yr.

    In St Charles County, MO, current lease rates show:

    • Office Properties & Spaces positioned at $24
    • Retail properties measuring $16
    • Individual retail properties assessed at $15
    • Office space calculated at $17
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    Commercial real estate by market

    Browse Commercial real estate for Lease Near St Charles, MO

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