Sign Up Successful!
You now have access to more from Realmo!
    For Lease
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Space Uses
    • Retail
    • Restaurant
    • Office
    • Coworking
    • Medical Space
    • Automotive
    • Industrial
    • Warehouse
    • Flex
    Price
    Price range
    $
    $
    Size
    Property size / sq.ft.
    AI Search

    Scott County, MO Commercial Real Estate for Lease

    Notify Me
    List
    Map
    Downtown Sikeston Commercial Property
    $4,500 / Mo
    4,273 SF

    Downtown Sikeston Commercial Property

    202 S Kingshighway St, Sikeston, MO 63801

    Versatile commercial space in downtown Sikeston ready for lease.

    • Prime downtown Sikeston location on a corner lot.
    • Large 7,638 sq ft building suitable for various business purposes.
    • Handicap accessible with ramp, parking, and restrooms.
    • Includes 15 parking spaces (2 handicap accessible).
    • Flexible layout with open spaces, offices, conference room, and break room.
    Updated: Jul 10, 2025
    View details
    Sikeston Warehouse Space Available
    $5,000 / Mo
    20,000 SF

    Sikeston Warehouse Space Available

    300 Matthews Ln, Sikeston, MO 63801

    Warehouse space for lease in Sikeston, Missouri.

    • Versatile Space: Option for two separate units (20,000 sf and 4,700 sf) or combined into one.
    • High Ceiling: Benefit from the 18' ceiling height in the 20,000 sf front unit.
    • Multiple Loading Docks: Features 2 dock doors with levelers and three 12 x 14 overhead doors.
    • Large Front Unit: 20,000 sf front unit with 25' bays and concrete floor.
    • Functional Back Unit: 4,700 sf back unit includes a shop area, 3 offices, 3 bathrooms, and lockable storage.
    Updated: Oct 24, 2025
    View details
    Sikeston Warehouse Space Available
    $1,500 / Mo
    4,700 SF

    Sikeston Warehouse Space Available

    Warehouse space for rent in Sikeston, Missouri.

    300 Matthews Ln, Sikeston, MO 63801
    View details
    Sikeston Office Suite For Rent
    $3,625 / Mo
    2,000 SF

    Sikeston Office Suite For Rent

    Recently-built office suite with four offices, bathroom, and kitchenette.

    912 S Main St, Sikeston, MO 63801
    View details
    Retail Space in Sikeston, MO
    $12 SF/Yr
    2,900 SF

    Retail Space in Sikeston, MO

    Retail space available in grocery store anchored shopping center.

    925-1077 Malone Ave, Sikeston, MO 63801
    View details
    Based on your search, we've compiled 30 Potential Opportunities for your consideration. Besides 5 Active listings in Scott County, MO, we suggest exploring alternatives. Similar 24 Properties for Sales.

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Commercial Land with Highway Frontage
    $12,500 / Mo
    55,757 SF

    Prime Commercial Land with Highway Frontage

    High-visibility commercial land with established business history and highway frontage.

    1105 S Main St, Sikeston, MO 63801
    View details

    Explore Similar Spaces for Sale in Scott County, MO

    Consider Similar Space for Sale. We found 24 Spaces in Nearby Locations matching your search parameters.

    Sikeston Commercial Property For Sale
    $600,000
    1.30 Acres

    Sikeston Commercial Property For Sale

    Income-producing property with commercial spaces and storage units.

    2008 N Main St, Sikeston, MO 63801
    View details
    Historical Building in Downtown Sikeston
    $269,000
    6,321 SF

    Historical Building in Downtown Sikeston

    Two-story historic building in downtown Sikeston, ideal for investors.

    112 Front St, Sikeston, MO 63801
    View details
    Downtown Sikeston Commercial Office Building
    $279,000
    4,273 SF

    Downtown Sikeston Commercial Office Building

    Commercial property with endless business opportunities in downtown Sikeston.

    202 S Kingshighway St, Sikeston, MO 63801
    View details
    Sikeston Industrial Warehouse on 8+ Acres
    $350,000
    10,000 SF

    Sikeston Industrial Warehouse on 8+ Acres

    Industrial warehouse with I-55 frontage, ideal for logistics or distribution.

    608b State Highway H, Miner, MO 63801
    View details
    Sikeston Commercial Property For Sale
    $650,000
    1.28 Acres

    Sikeston Commercial Property For Sale

    Prime commercial location with high visibility and established business history.

    1105 S Main St, Sikeston, MO 63801
    View details
    Historic Downtown Sikeston Retail Opportunity
    $299,000
    14,642 SF

    Historic Downtown Sikeston Retail Opportunity

    Two-story retail space in historic downtown Sikeston, Missouri.

    124 E Front St, Sikeston, MO 63801
    View details
    Sikeston Retail Property For Sale
    $550,000
    1,150 SF

    Sikeston Retail Property For Sale

    Established family-owned business with high visibility for over 30 years.

    1018 Linn St, Sikeston, MO 63801
    View details
    Sikeston Car Wash with Expansion Potential
    $1,000,000
    40,511 SF

    Sikeston Car Wash with Expansion Potential

    Turnkey car wash with expansion potential in high-demand market.

    531 N Main St, Sikeston, MO 63780
    View details
    Sikeston Warehouse with Highway Access
    $1,100,000
    24,700 SF

    Sikeston Warehouse with Highway Access

    Large warehouse with easy access to I-55 and I-57.

    300 Matthews Ln, Sikeston, MO 63801
    View details
    Sikeston Fourplex with Income Potential
    $360,000
    0.26 Acres

    Sikeston Fourplex with Income Potential

    Fourplex in Sikeston, MO with long-term tenants and income potential.

    416 Lake St, Sikeston, MO 63801
    View details
    Sikeston Carwash with High Visibility
    $1,250,000
    40,946 SF

    Sikeston Carwash with High Visibility

    Turnkey carwash with high traffic, visibility, and recurring revenue.

    900 S Main St, Sikeston, MO 63801
    View details
    Retail Property in Benton, MO
    $145,000
    0.70 Acres

    Retail Property in Benton, MO

    Retail property available for sale in Benton, Missouri.

    1879 County Highway 403, Benton, MO 63736
    View details
    Sikeston Commercial Property with Duplex
    $320,000
    4,244 SF

    Sikeston Commercial Property with Duplex

    Commercial building, duplex, and storage on a large lot.

    101-103 Donald Fulton Dr, Sikeston, MO 63801
    View details
    Spacious Home on Large Lot
    $114,900

    Spacious Home on Large Lot

    Three-bedroom home on a 1/3 acre lot.

    703 Cape St, Scott City, MO 63780
    View details
    Sikeston Flex Space: Prime Industrial
    $460,000
    19,498 SF

    Sikeston Flex Space: Prime Industrial

    19,498 SF Flex Building, 1.8 Acres

    205 New Madrid St, Sikeston, MO 63801
    View details
    Sikeston Commercial Building - Huge Potential
    $460,000
    1.80 Acres

    Sikeston Commercial Building - Huge Potential

    Versatile facility, ample parking, leaseback option.

    205 New Madrid St, Sikeston, MO 63801
    View details
    Sikeston Commercial Building For Sale
    $239,000

    Sikeston Commercial Building For Sale

    Prime Sikeston location, great investment opportunity.

    1637 Malone Ave, Sikeston, MO 63801
    View details

    Scott County, MO Commercial Real Estate Leasing Opportunities Market Analysis

    Explore Commercial Real Estate leasing options in Scott County, MO with 29 listings featured on our commercial real estate exchange. The current inventory includes 3,904,274,122 square feet of properties with an estimated lease value of $55 SF/Yr.

    Estimated lease rates for Commercial Real Estate in Scott County, MO begin at $2 SF/Yr, with an average of $9 SF/Yr and extend to $21 SF/Yr.

    In Scott County, MO, current lease rates show:

    • Retail properties positioned at $12
    • Industrial properties measuring $3
    • Office Properties & Spaces assessed at $17
    • Office space calculated at $17
    List
    Map

    Commercial real estate by market

    Browse Commercial real estate for Lease Near Scott, MO

    Popular Searches in Scott

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Create New Password
    • At least 8 characters
    • Contains both letters and numbers
    • Contains uppercase and lowercase letters
    • At most 32 characters
    • Password required
    • Password reset link has expired. Please request a new one.