South Portland, ME Commercial Real Estate for Lease

$7 SF/Yr

2,400 SF

South Portland Industrial/Flex Space

1 Runway Rd, South Portland, ME 04106

2,400± SF industrial/flex space for lease in South Portland.

• 2,400± SF of industrial/flex space available for lease.
• Located in South Portland.
• Proximity to US Route 1 and Pleasant Hill Road.
• Approximately two miles from Maine Turnpike Exit 45 (I‑95).
• Close to I‑295.

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Updated: Jan 20

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$20 SF/Yr

4,200 SF

Updated Medical Spa Space Available

198 Maine Mall Rd, South Portland, ME 04106

Recently updated medical spa, salon, or medical space for lease.

• Recently updated medical spa buildout, ready for immediate use.
• Excellent location suitable for medical spa, salon, or medical user.
• High visibility location between Exits 45 and 46 of the Maine Turnpike.
• High traffic count of 40,000± vehicles/day.
• Existing layout includes eight treatment rooms, four with sinks.

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Updated: Mar 25, 2025

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$14 SF/Yr

28,175 SF

Class A Office Space, South Portland

Prime Office Suites, Greater Portland

778 Main St, South Portland, ME 04074

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$15 SF/Yr

32,803 SF

Class A Office Space, South Portland

Prime Office Suites, Maine Turnpike Access

600 Southborough Dr, South Portland, ME 04106

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$26 SF/Yr

17,071 SF

South Portland Medical Office Building

Prime Medical Office Space Available

244 Western Ave, South Portland, ME 04106

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98,401 SF

Mallside Plaza Retail Space

Prime South Portland retail/restaurant opportunity.

198 Maine Mall Rd, South Portland, ME 04106

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$14 SF/Yr

95,457 SF

Executive Office Space, South Portland

Class A Office Suites, Ample Parking

600 Sable Oaks Dr, South Portland, ME 04106

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$15 SF/Yr

58,995 SF

Prime South Portland Office Space

Class A Office, 49,891+ SF Available

179 John Roberts Rd, South Portland, ME 04106

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$14 SF/Yr

36,972 SF

75 John Roberts Road Office Space

Class A Office, 8,114 SF Available

75 John Roberts Rd, South Portland, ME 04106

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$14 SF/Yr

42,000 SF

South Portland Industrial Campus

Maine Manufacturing Space Available

95 Darling Ave, South Portland, ME 04106

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$13 SF/Yr

116,600 SF

South Portland Executive Office Suite

Class A Office Space Available Now

82 Running Hill Rd, South Portland, ME 04106

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$10 SF/Yr

39,860 SF

1 Madison St

Distribution properties • 39,860 SF

1 Madison St, South Portland, ME 04106

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$14 SF/Yr

42,000 SF

South Portland Warehouse Space For Lease

Food-focused industrial space available.

95-97 Darling Ave, South Portland, ME 04106

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$8 SF/Yr

74,400 SF

South Portland Industrial Space For Lease

44,400 SF Manufacturing/Warehouse Space

165 Pleasant Ave, South Portland, ME 04106

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9,773 SF

Prime South Portland Retail Space

Maine Mall Shopping Center - For Lease

364 Maine Mall Rd, South Portland, ME 04106

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$7 SF/Yr

52,610 SF

Executive Office Space, South Portland

Modern Office Suites, Prime Location

1 Runway Rd, South Portland, ME 04106

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$25 SF/Yr

1,955 SF

Prime South Portland Retail Space

High-traffic shopping center, ample parking.

364 Maine Mall Rd, South Portland, ME 04106

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$15 SF/Yr

21,000 SF

Prime Commercial Space - Broadway

Retail, warehouse, office space available.

2325 Broadway, South Portland, ME 04106

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$9 SF/Yr

23,750 SF

Sublease: South Portland Office Space

16,912 SF Class A Office Sublease

78 Atlantic Pl, South Portland, ME 04106

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$28 SF/Yr

30,000 SF

Gorham Road Retail Space

Prime South Portland Retail Opportunity

430 Gorham Rd, South Portland, ME 04106

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$10 SF/Yr

100,982 SF

Jetport Plaza: Retail Space Available

Prime South Portland retail center, 100,982 sqft.

443 Western Ave, South Portland, ME 04106

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$21 SF/Yr

66,000 SF

Sable Oaks Office Space Available

Class A office suites, South Portland, ME.

707 Sable Oaks Dr, South Portland, ME 04106

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$13 SF/Yr

8,000 SF

Prime South Portland Office/Flex Space

8,000 SF Single-Tenant Office Building in Cummings Road Business Park

236 Gannett Dr, South Portland, ME 04106

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$15 SF/Yr

5,500 SF

South Portland Flex/Retail Space

5,500± SF office/retail with warehouse, near I-295.

2325 Broadway, South Portland, ME 04106

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