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Des Moines, IA Commercial Real Estate for Lease

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221 results
Hub Tower
Contact for pricing

Hub Tower

Discover many ways to work your way in Hub Tower

699 Walnut St, Unit 400, Des Moines, IA 50309
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Downtown Des Moines Office Space
$19 SF/Yr
14,360 SF

Downtown Des Moines Office Space

500 Southwest 7th Street, Des Moines, IA 50309

Three-story office building in vibrant Riverpoint district with parking.

  • Lowest fully serviced lease rate available for comparable downtown properties.
  • Free on‑site surface parking available.
  • Up to 14,360 SF of Contiguous Space.
  • Centrally located South of Des Moines’ Central Business District, adjacent to new living and retail amenities.
  • Attractive open foyer providing an abundance of natural light.
Updated: Mar 25
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Former Fitness Center on Fleur
$10 SF/Yr
4,847 SF

Former Fitness Center on Fleur

4301 Fleur Drive, Des Moines, IA 50321

Former fitness center available for lease in Wakonda Shopping Center.

  • Existing gym infrastructure reduces build‑out costs.
  • High‑traffic location on Fleur Drive with excellent visibility.
  • Strong co‑tenancy with established retailers.
  • Ample parking with main entrance across from Fareway entrance.
  • Convenient access to Fleur Drive and proximity to major employers and the airport.
Updated: Mar 25
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East Euclid Avenue Flex Space
$12 SF/Yr
8,500 SF

East Euclid Avenue Flex Space

Former tire service center suitable for auto, retail, or flex.

1566 East Euclid Avenue, Des Moines, IA 50313
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Ingersoll Avenue Retail Space Available
$12 SF/Yr
6,084 SF

Ingersoll Avenue Retail Space Available

Retail space for lease on streetscaped Ingersoll Avenue.

2913 Ingersoll Avenue, Des Moines, IA 50312
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IA, Des Moines - Grand Ave
Contact for pricing

IA, Des Moines - Grand Ave

Flexible workspace in NV, Reno - 300 E 2nd St

2323 Grand Ave, Des Moines, IA 50312
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Retail Space on Ingersoll Avenue
$20 SF/Yr
6,270 SF

Retail Space on Ingersoll Avenue

Retail space in Soll Apartments near Ingersoll shopping corridor.

2301 Ingersoll Avenue, Des Moines, IA 50312
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Office Space Near Sculpture Park
$12 SF/Yr
6,401 SF

Office Space Near Sculpture Park

Office space for rent near downtown Des Moines attractions.

1300 Walnut Street, Des Moines, IA 50309
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East Village Mixed-Use Development
$14 SF/Yr
2,639 SF

East Village Mixed-Use Development

New mixed-use development with commercial space in the East Village.

201 Southeast 6th Street, Des Moines, IA 50309
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Freestanding Retail Space on Corner
$24 SF/Yr
4,092 SF

Freestanding Retail Space on Corner

Retail property with high visibility and existing restaurant infrastructure.

4212 Merle Hay Road, Des Moines, IA 50310
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Historic Office Building in Des Moines
$17 SF/Yr
7,689 SF

Historic Office Building in Des Moines

Two-story office building with unique architecture and high-end finishes.

1420 Locust Street, Des Moines, IA 50309
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Des Moines Flex/Industrial Building
$9 SF/Yr
15,034 SF

Des Moines Flex/Industrial Building

15,034 SF office/warehouse on 1.18-acre lot.

1801 2nd Ave, Des Moines, IA 50314
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High Visibility Retail/Office Space
$15 SF/Yr
6,650 SF

High Visibility Retail/Office Space

Retail or medical office space in a high-traffic location.

6201 Southeast 14th Street, Des Moines, IA 50320
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Prime Retail Space Near Park
$4,400 /Mo
2,450 SF

Prime Retail Space Near Park

Retail space near sculpture park, high visibility, foot traffic.

1301 Locust Street, Des Moines, IA 50309
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Commercial Flex Space For Lease
$8 SF/Yr
8,760 SF

Commercial Flex Space For Lease

Commercial/Flex property for lease with great visibility and industrial zoning.

3296 NW Prairie Lane, Des Moines, IA 50313
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Historic Office Space For Lease
$10 SF/Yr
2,208 SF

Historic Office Space For Lease

Historic office condo in vibrant Court Avenue District available for lease.

100 Court Avenue, Des Moines, IA 50309
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Class A Office Retail Building
$8 SF/Yr
158,557 SF

Class A Office Retail Building

Eight-story Class A office and retail building in downtown Des Moines.

400 Locust Street, Des Moines, IA 50309
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Versatile Corporate Headquarters Location
$8 SF/Yr
36,071 SF

Versatile Corporate Headquarters Location

Adaptable spaces with convenient access and nearby amenities.

535 Southwest 7th Street, Des Moines, IA 50309
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Mixed-Use Development in Downtown
$20 SF/Yr
7,066 SF

Mixed-Use Development in Downtown

Five-story mixed-use development offering urban living and commercial space.

1301 Mulberry Street, Des Moines, IA 50309
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Retail Space with Ample Parking
$25 SF/Yr
11,050 SF

Retail Space with Ample Parking

Retail space available for rent with tenant improvement allowance.

1111 East 14th Street, Des Moines, IA 50316
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Restaurant Space with Existing Infrastructure
$29 SF/Yr
1,600 SF

Restaurant Space with Existing Infrastructure

Second-generation restaurant space with FF&E and grease interceptor.

2708 Ingersoll Avenue, Des Moines, IA 50312
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Des Moines Flex Space Available
$5 SF/Yr
8,344 SF

Des Moines Flex Space Available

Multi-tenant flex building near Des Moines CBD for lease.

601 Southwest 9th Street, Des Moines, IA 50309
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Retail Space on Army Post
$6 SF/Yr
14,600 SF

Retail Space on Army Post

Retail space with high visibility and ample parking.

1000-1040 E Army Post Rd, Des Moines, IA
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Des Moines Office Space Available
$20 SF/Yr
6,228 SF

Des Moines Office Space Available

6,228 SF office space for sublease in Des Moines.

220 SW 9th St, Des Moines, IA
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Des Moines, IA Commercial real estate Leasing Opportunities Market Analysis

Explore Commercial real estate leasing options in Des Moines, IA with 221 listings featured on our commercial real estate exchange. The current inventory includes 35,417,329,200 square feet of properties with an estimated lease value of $750 /Mo.

Estimated lease rates for Commercial real estate in Des Moines, IA begin at $1.50 SF/Yr, with an average of $14 SF/Yr and extend to $29 SF/Yr.
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