San Mateo County, CA Commercial Real Estate for Lease

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Move-In Ready Full-Floor Office
Move-In Ready Full-Floor Office

55 2nd St, San Francisco, CA 94105

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16,538 sqft

Full-floor office with training rooms, conference rooms, kitchen, production area, and open workstation space.

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Menlo Park Office Space Available
Menlo Park Office Space Available

2885 Sand Hill Road, Menlo Park, CA 94025

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11,168 sqft

Office space for rent with views of the western hills.

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Medical Office Suite with Parking
Medical Office Suite with Parking

490 Post St, San Francisco, CA 94102

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1,007 sqft

Medical office space in a 24/7 secured building with paid parking options and strong BART and Muni access nearby.

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Office Building with Lease Options
Office Building with Lease Options

1875 S Grant St, San Mateo, CA 94402

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1,138 sqft

Crossroads II offers lease or sublease office space ranging from 1,415 to 18,282 SF.

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Tandem 4th-Floor Office Suite
Tandem 4th-Floor Office Suite

220 Montgomery St, San Francisco, CA 94104

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467 sqft

Tandem office suite on the 4th floor configured for 2 to 4 people in a practical, well-lit layout.

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Full-Floor Office Suite
Full-Floor Office Suite

44 Montgomery St, San Francisco, CA 94104

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15,584 sqft

Full-floor office layout with extensive windowline, meeting rooms, phone rooms, and open work area for about 95 workstations.

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South San Francisco Office/Lab Space
South San Francisco Office/Lab Space

180 Kimball Way & 442 Littlefield Ave, South San Francisco, CA 94080

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85,140 sqft

Office and laboratory spaces in South San Francisco.

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Office Suite with Open Work Area
Office Suite with Open Work Area

201 3rd St, San Francisco, CA 94103

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15,304 sqft

Office space offers an open area for 95+ workstations plus nine private offices and meeting rooms.

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South San Francisco Life Science Campus
South San Francisco Life Science Campus

East Grand Ave & Harbor Way, South San Francisco, CA 94080

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226,763 sqft

Class A life science campus in South San Francisco.

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Civic Center Full Building
Civic Center Full Building

50 Brady Street, San Francisco, CA 94103

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2,000 sqft

Full building in the heart of the Civic Center neighborhood.

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Small Office Suites
Small Office Suites

391 Sutter St, San Francisco, CA 94108

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953 sqft

Small office suites are available for lease at 391 Sutter St in San Francisco’s Union Square area.

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Class A Office Building
Class A Office Building

6000 Shoreline Court, South San Francisco, CA 94080

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31,852 sqft

Class A office building in South San Francisco life science market.

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Freestanding Industrial Building For Lease
Freestanding Industrial Building For Lease

60 Airport Boulevard, South San Francisco, CA 94080

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36,000 sqft

36,000 SF industrial building with freeway access.

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Renovated Storefront Property
Renovated Storefront Property

1412 Stockton St, San Francisco, CA 94133

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1,295 sqft

Recently updated commercial space with adaptable configuration, rear storage, and a private restroom.

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Office Building with Terrace Garden
Office Building with Terrace Garden

456-460 Montgomery St, San Francisco, CA 94104

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3,716 sqft

Modern aluminum and glass office tower cantilevered over two 1907 beaux-arts banking temples with terraced gardens and on-site management.

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Class A Plug-and-Play Office Units
Class A Plug-and-Play Office Units

825 Industrial Rd, San Carlos, CA 94070

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Sublease space is available within Alexandria Center for Life Science.

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Office Suite with Conference Room
Office Suite with Conference Room

3 Embarcadero Ctr, San Francisco, CA 94111

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4,218 sqft

Office suite features four private offices, a large conference room, open work area, and double door entry.

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South San Francisco Office Space
South San Francisco Office Space

490 Forbes Boulevard, South San Francisco, CA 94080

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107,175 sqft

Move-in ready office suites available in South San Francisco.

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Versatile Flex Space Available 2025
Versatile Flex Space Available 2025

350 Harbor Blvd, Belmont, CA

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27,590 sqft 12.39 AC lot

27,590 SF flex space with office, R&D, warehousing zoning.

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Office Suite with Four Private Offices
Office Suite with Four Private Offices

220 Montgomery St, San Francisco, CA 94104

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1,754 sqft

Office suite features four private offices, a large conference room, and a reception/waiting area.

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Retail Space Near Caltrain Station
Retail Space Near Caltrain Station

520 El Camino Real, San Carlos, CA 94070

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1,757 sqft

New retail spaces across from San Carlos Caltrain Station.

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Office Suite with Roof Deck
Office Suite with Roof Deck

369 Pine St, San Francisco, CA 94104

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1,071 sqft

Suite includes reception, five private offices, a kitchen, and a roof deck with stair-only access.

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Single-Tenant Office Space
Single-Tenant Office Space

San Francisco, CA 94114

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Lease a single-tenant office space on Castro Street in San Francisco’s Upper Noe Valley area.

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Mission Bay Class-A Office Space
Mission Bay Class-A Office Space

455 Mission Bay Boulevard South, San Francisco, CA 94158

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24,002 sqft

Class-A office space in amenity-rich Mission Bay neighborhood.

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