San Diego, CA Commercial real estate for Rent & Lease

$129-$7,736/Mo

(972) 764-8885

888 Prospect Street

Discover many ways to work your way in 888 Prospect Street

888 Prospect St, Unit 200, La Jolla, CA 92037

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$129-$8,154/Mo

(972) 764-8885

Liberty Station

Discover many ways to work your way in Liberty Station

2305 Historic Decatur Rd, Unit 100, San Diego, CA 92106

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$129-$5,205/Mo

(972) 764-8885

Cush Plaza

Discover many ways to work your way in Cush Plaza

10620 Treena St, Unit 230, San Diego, CA 92131

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$129-$3,715/Mo

CA, San Diego - 770 First Avenue

770 1St Ave, Unit 250, San Diego, CA 92101

Discover many ways to work your way in CA, San Diego - 770 First Avenue

Be part of a vibrant coworking community with dedicated desk or hot desking options in thousands of idyllic locations across the globe
Grow in a modern workplace with the added advantage of a benefits program offering exclusive discounts and bespoke procurement support
Access Regus' network of workspaces and business lounges as often as you need and take advantage of their exclusive benefits
Impress clients, hold memorable workshops, and deliver a winning pitch in Regus' meeting spaces, fully equipped for gatherings of any size
Collaborate with like‑minded professionals and enjoy regular networking and community events with a Regus membership

Updated: Feb 19

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$129-$8,887/Mo

CA, San Diego - Camino del Rio N

2650 Camino Del Rio, San Diego, CA 92108

Workspaces, services and support to help you grow your business in CA, San Diego - Camino del Rio N

Make a home for yourself and your team in a private office, fully serviced and flexible, with everything included
Grow in a modern workplace with the added advantage of a benefits program offering exclusive discounts and bespoke procurement support
Find your own private desk in a beautifully designed shared workspace with 24/7 access, a personal locker, and an inviting reception team
Virtual offices allow you to establish a presence at any Spaces location worldwide with mail handling, a virtual call assistant, and on‑demand access
Spaces' meeting rooms have everything you need from audiovisual equipment, whiteboards, and Wi‑Fi to food and beverage services

Updated: Feb 19

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$129-$7,103/Mo

Spaces University Town Center

Workspaces, services and support to help you grow your business in Spaces University Town Center

4660 La Jolla Village Dr, San Diego, CA 92122

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$129-$7,966/Mo

Mission Valley - Stonecrest

Discover many ways to work your way in Mission Valley - Stonecrest

9655 Granite Ridge Dr, Unit 200, San Diego, CA 92123

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$129-$4,113/Mo

Sunroad Corporate Center

Meet, work or collaborate in our professional Sunroad Corporate Center business center

4445 Eastgate Mall, Unit 200, San Diego, CA 92121

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$129-$4,887/Mo

Spaces Makers Quarter

Find fully flexible work and meeting space in Spaces Makers Quarter

845 15Th St, San Diego, CA 92101

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$129-$8,734/Mo

One Pacific Heights

Discover many ways to work your way in One Pacific Heights

9920 Pacific Heights Blvd, Unit 150, San Diego, CA 92121

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$129-$4,019/Mo

501 W. Broadway

Discover many ways to work your way in 501 W. Broadway

501 Broadway, Unit 800, San Diego, CA 92101

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$129-$7,569/Mo

Mission Valley

Discover many ways to work your way in Mission Valley

3111 Camino Del Rio, Unit 400, San Diego, CA 92108

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$129-$3,341/Mo

Emerald Plaza

Discover many ways to work your way in Emerald Plaza

402 Broadway, Unit 400, San Diego, CA 92101

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$129-$4,006/Mo

Diamond View

Discover many ways to work your way in Diamond View

350 10Th Ave, Unit 1000, San Diego, CA 92101

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$129-$7,216/Mo

CA, San Diego - Texas St

Discover many ways to work your way in CA, San Diego - Texas St

5005 Texas St, Unit 100, San Diego, CA 92108

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$9,500/Mo

4,400 SF

Storefront Retail Lease Space

Retail storefront with fenced parking and brand-new interior finishes, offered on a gross basis starting June 2026.

3220 Adams Ave, San Diego, CA 92116

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$1.70 SF/Yr

18,732 SF

Freestanding Flex/Industrial Building

Single-story warehouse with rooftop HVAC, grade-level loading, and outdoor areas for operational and production needs.

10109 Carroll Canyon Road, San Diego, CA 92131

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$350/Mo

14,892 SF

SmartSpace: Office and Art Gallery

Office space in an art gallery with collaborative environment.

4455 Murphy Canyon Road Suite 100, San Diego, CA 92123

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$2.00 SF/Yr

26,457 SF

Remodeled Office Space in San Diego

Recently remodeled office space with modern updates and exceptional convenience.

4010 Morena Blvd., San Diego, CA 92117

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$1.90 SF/Yr

33,862 SF

Kearny Mesa HQ and Warehouse

Corporate HQ with warehouse space in Kearny Mesa.

7520 Mission Valley Road, San Diego, CA 92108

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$2 SF/Yr

13,739 SF

Prominent Office Space For Rent

High-visibility office space with modern facade and landscaping.

10875 Rancho Bernardo Rd, San Diego, CA 92127

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$19 SF/Yr

6,130 SF

Miramar Flex Space Available

Flex space in Miramar available 9/1/2026 with excellent freeway access.

9350-9372 Cabot Dr, San Diego, CA 92126

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$850/Mo

Pacific Beach Furnished Office Space

Furnished office spaces available in Pacific Beach with included amenities.

4526 CASS St, San Diego, CA 92109

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$2 SF/Yr

2,376 SF

Downtown Office Space For Lease

Downtown office building for lease with renovation and parking.

185 W F St, San Diego, CA

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San Diego, CA Commercial real estate Leasing Opportunities Market Analysis

Explore Commercial real estate leasing options in San Diego, CA with 1400 listings featured on our commercial real estate exchange. The current inventory includes 4,301,470 square feet of properties with an estimated lease value of $40,156.

Estimated lease rates for Commercial real estate in San Diego, CA begin at $0.75 SF/Yr, with an average of $84 SF/Yr and extend to $33,000.