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Acton, MA Retail Properties & Spaces for Lease

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15 results
Medical & Professional Suites Available
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1,352 SF

Medical & Professional Suites Available

411 Massachusetts Ave, Acton, MA 1720

Medical and professional suites for lease in Acton, Massachusetts.

  • Prime location directly off Route 2 at the intersection of Route 27 and Route 111, providing convenient regional access.
  • Ample on‑site parking for employees, patients, and visitors.
  • Amenity‑rich surroundings with an adjacent shopping plaza anchored by Roche Bros., TJ Maxx, HomeGoods, and Not Your Average Joe’s.
  • Well‑maintained building occupied by a network of medical and professional users.
  • Suites available on multiple floors (2nd and 3rd) with varying square footage options.
Updated: Mar 6
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Retail/Medical Space Near Route 2
$21 SF/Yr
3,000 SF

Retail/Medical Space Near Route 2

222 Main St, Acton, MA 1720

Freestanding building with retail/medical space, superb visibility, easy access.

  • Superb visibility and easy accessibility for customers.
  • Prime location: Less than 1/4 mile from Route 2 (exit 42) and the Acton Commuter Rail (MBTA) station.
  • Suitable for medical or retail use with approximately 3,000 sq ft of space.
  • Recent building improvements in 2018: new roof, HVAC, exterior painting, and sidewalk.
  • Located in a plaza with established businesses: Dunkin Donuts, hardware store, and restaurant.
Updated: Jul 31, 2025
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Retail Space Near Stop & Shop
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Retail Space Near Stop & Shop

Retail space available near Stop & Shop and affluent communities.

Acton, MA 01720
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Retail/Office Space in Acton
$19 SF/Yr
16,800 SF

Retail/Office Space in Acton

3,000 SF retail/office space available in Acton, MA.

77 Powder Mill Road, Acton, MA 01720
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Prime Retail Space on Great Road
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4,000 SF

Prime Retail Space on Great Road

Highly visible retail space in a heavily trafficked corridor.

425 Great Rd, Acton, MA
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Retail Space in Acton, MA
$19 SF/Yr
3,000 SF

Retail Space in Acton, MA

3,000 SF retail space available for lease.

77 Powdermill Rd, Acton, MA
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Retail Space Near Route 111
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2,478 SF

Retail Space Near Route 111

2,478 SF endcap retail space with high visibility.

411 Massachusetts Ave, Acton, MA
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Retail Space in Acton Center
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1,220 SF

Retail Space in Acton Center

Retail space available in a busy Acton shopping center.

100 Powder Mill Rd, Acton, MA
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Retail Space in Acton Center
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23,000 SF

Retail Space in Acton Center

Neighborhood retail shopping center anchored by Donelan’s Supermarket.

246-266 Great Rd, Acton, MA
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Retail Space Available For Lease
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Retail Space Available For Lease

Retail property available for lease.

252 Main St, Acton, MA 1720
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Retail Space in Acton Plaza
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2,990 SF

Retail Space in Acton Plaza

Grocery-anchored neighborhood center in affluent Acton, MA.

201-393 Massachusetts Ave, Acton, MA
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Retail Spaces Available For Rent
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6,500 SF

Retail Spaces Available For Rent

Retail spaces available, ranging from 2,400 to 6,500 SqFt.

400 Massachusetts Ave, Acton, MA 1720
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Brookside Shops Retail Opportunity
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75,529 SF

Brookside Shops Retail Opportunity

Retail spaces in a busy shopping center with high visibility.

145 Great Rd, Acton, MA 1720
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Retail Space Available For Lease
$15 SF/Yr
2,493 SF

Retail Space Available For Lease

Retail property with 2493 square feet available for lease.

436 Great Rd, Acton, MA
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Retail/Office Space in Acton
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2,493 SF

Retail/Office Space in Acton

2,493 sq ft retail/office space ready for customization.

436 Great Rd, Acton, MA 1720
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Based on your search, we've compiled 32 Potential Opportunities for your consideration. Besides 15 Active listings in Acton, MA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 9 Properties for Sales.

Explore Retail properties & Spaces for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Retail Space Available For Rent
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5,000 SF

Retail Space Available For Rent

Single tenant retail space available, approximately 5,000 square feet.

768 Elm St, Concord, MA 1742
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Retail Space in Maynard Crossing
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2,749 SF

Retail Space in Maynard Crossing

Retail space available in a mixed-use, open-air development.

9 Digital Wy, Maynard, MA
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Retail Space on Route 62
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Retail Space on Route 62

Retail space with excellent visibility in affluent Maynard area.

86 Powder Mill Rd, Maynard, MA 1754
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Retail Strip in West Concord
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11,804 SF

Retail Strip in West Concord

Multi-tenant retail strip with office space in Concord, MA.

135 Commonwealth Ave, Concord, MA 1742
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Explore Similar Spaces for Sale in Acton, MA

Consider Similar Space for Sale. We found 9 Spaces matching your search parameters.

Retail Property in Acton, MA
$895,000
3,304 SF

Retail Property in Acton, MA

Retail property featuring 3,304 square feet in Acton, MA.

457 Great Rd, Acton, MA
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Acton Commercial Property For Sale
$895,000
3,304 SF

Acton Commercial Property For Sale

Commercial property on Great Road suitable for various business purposes.

457 Great Rd, Acton, MA 1720
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Established Retail Building on 2A
$1,100,000
4,186 SF

Established Retail Building on 2A

Boutique retail building with high visibility and conversion potential.

6 Great Road, Acton, MA 1720
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Historic Landmark with Prime Frontage
$1,500,000

Historic Landmark with Prime Frontage

Historic landmark with excellent visibility in a vibrant commercial area.

144 Great Road, Acton, MA 1720
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Retail Property in Acton, MA
Contact for pricing
4,233 SF

Retail Property in Acton, MA

Retail property with 4,233 square feet of space.

178 Great Rd, Acton, MA
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West Acton Village Retail Condo
$259,900
1,496 SF

West Acton Village Retail Condo

Prime commercial condo in vibrant West Acton, ideal for retail.

25 Spruce Street #A, Acton, MA 1720
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Historic Landmark on Great Road
$1,500,000
5,637 SF

Historic Landmark on Great Road

Historic landmark with prime frontage, ideal for retail or office.

144 Great Rd, Acton, MA 1720
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5,000 SF Mixed-Use Building
$895,000
5,000 SF

5,000 SF Mixed-Use Building

Versatile building on Great Road with flexible zoning.

61 Great Rd, Acton, MA 1720
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Retail Building with Basement Storage
$1,100,000
3,012 SF

Retail Building with Basement Storage

Retail space with high visibility and potential residential conversion.

6 Great Rd, Acton, MA 1720
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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Versatile Lot for Lease
$8,000/Mo

Versatile Lot for Lease

9,627 sq ft lot suitable for various commercial uses.

25 Webster St, Brookline, MA 2446
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Retail Pad Development Site
$0.71 SF/Yr

Retail Pad Development Site

0.71 acre retail pad site for ground lease.

250 S Willow St, Manchester, NH 3103
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Concord, NH Commercial Land Lease
Contact for pricing

Concord, NH Commercial Land Lease

4.89 acre commercial land for lease in Concord, NH.

3 Intervale Road, Concord, NH 03301
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Prime Commercial Land in Schenectady
$23 SF/Yr
22,240 SF

Prime Commercial Land in Schenectady

High-visibility commercial land suitable for retail, office, or mixed-use development.

120 Erie Boulevard, Schenectady, NY 12305
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Acton, MA Retail properties & Spaces Leasing Opportunities Market Analysis

Explore Retail properties & Spaces leasing options in Acton, MA with 15 listings featured on our commercial real estate exchange. The current inventory includes 261,360,000 square feet of properties with an estimated lease value of $40 SF/Yr.

Estimated lease rates for Retail properties & Spaces in Acton, MA begin at $19 SF/Yr, with an average of $20 SF/Yr and extend to $21 SF/Yr.
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