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Acton, MA Office Spaces for Lease

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Retail Space with Pylon Signage
Updated: May 7
Retail Space with Pylon Signage

425 Great Rd, Acton, MA 01720

Contact for pricing
5,800 sqft
Pylon signage available
Warm vanilla shell delivery for flexible tenant buildout
Highly visible Great Road site on Route 119 / Route 2A
Approximately 16,000 vehicles per day on the corridor
5‑mile population of 58,524
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Medical & Professional Suites Available
Updated: Mar 6
Medical & Professional Suites Available

411 Massachusetts Ave, Acton, MA 01720

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1,352 sqft
Prime location directly off Route 2 at the intersection of Route 27 and Route 111, providing convenient regional access.
Ample on‑site parking for employees, patients, and visitors.
Amenity‑rich surroundings with an adjacent shopping plaza anchored by Roche Bros., TJ Maxx, HomeGoods, and Not Your Average Joe’s.
Well‑maintained building occupied by a network of medical and professional users.
Suites available on multiple floors (2nd and 3rd) with varying square footage options.
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Medical Office Space with ADA Access
Medical Office Space with ADA Access

411 Massachusetts Ave, Acton, MA 01720

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1,296 sqft

Move-in ready medical office space with ADA accessibility and rear parking lot access near major retail.

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ADA-Accessible Medical Office Suite
ADA-Accessible Medical Office Suite

411 Massachusetts Ave, Acton, MA 01720

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1,352 sqft

Move-in-ready medical office space with ADA accessibility and convenient rear parking lot access, with visibility from Route 111.

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Car-Dependent Office Space
Car-Dependent Office Space

289 Great Rd, Acton, MA 01720

$21 SF/Yr

For lease office space with walk score 45 and bike score 49, reflecting car-dependent access.

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Office Building With Lab Space
Office Building With Lab Space

125 Nagog Park, Acton, MA 01720

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Flexible commercial space combines office, laboratory, and flex configurations within an established business park setting.

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Three-Story Office Building
Three-Story Office Building

526 Main St, Acton, MA 01720

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5.30 AC lot

Office property with Route 27 access and proximity to commuter rail.

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Retail/Office Space in Acton
Retail/Office Space in Acton

436 Great Rd, Acton, MA 01720

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2,493 sqft

2,493 sq ft retail/office space ready for customization.

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Based on your search, we've compiled 19 Potential Opportunities for your consideration. Besides 8 Active listings in Acton, MA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 7 Properties for Sales.

Office Spaces for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Medical Office Suite with Treatment Rooms
Medical Office Suite with Treatment Rooms

56 Winthrop St Unit 1, Concord, MA 01742

$1,000/Mo

Flexible room-to-suite leasing supports healthcare and wellness practices.

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Second-Floor Office Suite
Second-Floor Office Suite

288 Littleton, Unit 23, Westford, MA 01886

$800/Mo
592 sqft

Second-floor office suite features two private offices, open reception area, and a restroom.

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Concord Office Space Available
Concord Office Space Available

23-43 Bradford St, Concord, MA

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5,340 sqft 1.99 AC lot

Office space available for lease in Concord, Massachusetts.

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Westford Retail/Office Space Available
Westford Retail/Office Space Available

439 Littleton Rd, Westford, MA

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1,000 sqft 2.06 AC lot

Retail/office space for lease in Westford, Massachusetts.

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Similar Spaces for Sale in Acton, MA

Consider Similar Space for Sale. We found 7 Spaces matching your search parameters.

Highly Visible Retail Shell
Highly Visible Retail Shell

425 Great Road, Acton, MA 01720

Contact for pricing
18,159 sqft

Warm vanilla shell retail space with pylon signage on a heavily trafficked corridor.

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Two-Property Medical Office Portfolio
Two-Property Medical Office Portfolio

321 Main Street, Acton, MA 01720

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31,764 sqft

Fully leased medical facilities offer NNN structures, scheduled rent increases, and limited ongoing landlord responsibilities.

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West Acton Village Retail Condo
West Acton Village Retail Condo

25 Spruce Street #A, Acton, MA 01720

$259,900
1,496 sqft

Prime commercial condo in vibrant West Acton, ideal for retail.

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Two-Unit Mixed-Use Building
Two-Unit Mixed-Use Building

6 Strawberry Hill Rd, Acton, MA 01720

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2,240 sqft 0.28 AC lot

Separate entrances and utilities allow the building to accommodate one or two businesses.

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Flex Research and Office Building
Flex Research and Office Building

15 Craig Rd, Acton, MA 01720

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16,185 sqft

Flex/RD building with office space, ventilated research/lab area, and an exterior loading dock door.

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Historic Landmark on Great Road
Historic Landmark on Great Road

144 Great Rd, Acton, MA 01720

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5,637 sqft

Historic landmark with prime frontage, ideal for retail or office.

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5,000 SF Mixed-Use Building
5,000 SF Mixed-Use Building

61 Great Rd, Acton, MA 01720

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5,000 sqft

Versatile building on Great Road with flexible zoning.

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Acton, MA Office Spaces Lease Rates & Market Statistics

Browse 8 Office Spaces for lease in Acton, MA on Realmo, a commercial real estate marketplace serving the Acton area. The current inventory totals 12,293 square feet of properties.

Asking lease rates for Office Spaces in Acton start at $21 SF/Yr, average $21 SF/Yr, and reach $21 SF/Yr at the top of the market. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings. The local average of $21 SF/Yr is 22% below the Massachusetts state average of $27.02 SF/Yr.

Acton accounts for 1% of the 1,381 office spaces currently available across Middlesex County, where nearby markets include Cambridge and Waltham. By space type, the market includes 4 medical office space listings and 3 office buildings.

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