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    Bluffton, SC Office Space for Sale

    12 results
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    Prime Commercial Site in Bluffton
    Contact for pricing

    Prime Commercial Site in Bluffton

    280 Old Bridge Dr, Bluffton, SC 29910

    Trophy site near new medical facilities in Bluffton, SC.

    • Located at the intersection of Buckwalter and Bluffton Parkway, a high‑traffic area.
    • Surrounded by three major medical developments: Novant (190,000 sqft), Beaufort Memorial (60,000 sqft), and MUSC (55,000 sqft).
    • Features two buildings: 13,600 sqft with drive‑thru and 18,600 sqft of retail/office space.
    • Adjacent to MUSC's 55,000 sqft medical facility.
    • Across the street from Novant's 190,000 sqft hospital.
    Updated: Jan 7
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    Bluffton Flex Space For Sale
    Contact for pricing

    Bluffton Flex Space For Sale

    1504 Fording Island Rd, Bluffton, SC 29910

    Flex space with office/retail and warehouse/storage near Hilton Head.

    • Prime location at the base of the bridge to Hilton Head Island.
    • Combination of warehouse/storage (2000 sqft) and office/retail space (2355 sqft).
    • Easy access with right in/right out on Hwy 278 and multiple access points.
    • 10 x 12 rollup door for convenient deliveries.
    • Signage available on Hwy 278.
    Updated: Oct 14, 2025
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    Bluffton Commercial Space For Sale
    Contact for pricing
    231,304 SF

    Bluffton Commercial Space For Sale

    Modern retail, office, and medical space near Hampton Lake entrance.

    3 Hampton Lake Dr, Bluffton, SC 29910
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    Bluffton Commercial Property For Sale
    Pending
    $593,450

    Bluffton Commercial Property For Sale

    Commercial property in Bluffton Village suitable for various business uses.

    14 Palmetto Way, Bluffton, SC 29910
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    Bluffton Office Condo For Sale
    Pending
    $299,000

    Bluffton Office Condo For Sale

    End-unit office condo in Plantation Commons Business Park.

    23 Plantation Park Dr, Bluffton, SC 29910
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    Office Space in Bluffton Village
    Pending
    $593,450

    Office Space in Bluffton Village

    Office space in central Bluffton location with flexible layout.

    14 Palmetto Way, Bluffton, SC 29910
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    Highway 170 Retail/Office/Medical Space
    Contact for pricing
    3,970 SF

    Highway 170 Retail/Office/Medical Space

    Retail, office, or medical space for sale on Highway 170.

    48 Ter Dr, Okatie, SC 29909
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    Highway Frontage Office/Showroom Space
    Contact for pricing
    85,878 SF

    Highway Frontage Office/Showroom Space

    Office/Showroom space for lease fronting Highway 278 in Bluffton.

    10 Buck Island Rd, Bluffton, SC 29910
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    Class A Office in Bluffton
    Contact for pricing
    3,747 SF

    Class A Office in Bluffton

    Class A office space for lease in Old Town Bluffton.

    212 Bluffton Rd, Bluffton, SC 29910
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    Flex Warehouse with Office Space
    Contact for pricing
    15 SF

    Flex Warehouse with Office Space

    10,200 SF flex warehouse with 2,400 SF office space.

    26 Buckingham Plantation Dr, Bluffton, SC 29910
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    Retail/Office/Medical Building For Sale
    Contact for pricing
    10,130 SF

    Retail/Office/Medical Building For Sale

    Pre-leasing retail/office/medical building in the heart of Bluffton.

    128 Bluffton Rd, Bluffton, SC 29910
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    Bluffton Retail or Office Space
    Contact for pricing
    1,650 SF

    Bluffton Retail or Office Space

    Retail or office space in the heart of Bluffton.

    10 Kitties Landing Rd, Bluffton, SC 29910
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    Based on your search, we've compiled 17 Potential Opportunities for your consideration. Besides 12 Active listings in Bluffton, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 1 Off-Market properties to explore as potential leads

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Hilton Head Commercial Space
    Contact for pricing

    Hilton Head Commercial Space

    1,500 sq ft commercial space for retail, office, storage.

    46 Old Wild Horse Rd, Hilton Head Island, SC 29926
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    Hilton Head Warehouse/Office Space
    Pending
    Contact for pricing
    5,000 SF

    Hilton Head Warehouse/Office Space

    Remodeled warehouse/office space in Hilton Head Island, ready to go.

    229 Gumtree Rd, Hilton Head Island, SC 29926
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    Beaufort SC Creative Office Space
    $620,000
    2,128 SF

    Beaufort SC Creative Office Space

    High-growth market, flexible zoning, great visibility.

    86 Sc-128, Beaufort, SC 29906
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    Commercial Property on Parris Island
    $1,900,000
    0.62 Acres

    Commercial Property on Parris Island

    Versatile commercial space in high-traffic Beaufort location.

    491 Parris Island Gtwy, Beaufort, SC 29906
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    Explore Off-Market Properties in Bluffton, SC

    Consider similar Off-Market properties in Bluffton, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    29 Plantation Park Dr

    29 Plantation Park Dr

    Office space
    Value Estimation by Request
    29 Plantation Park Dr, Bluffton, SC 29910
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    Bluffton, SC Office Space Investment Opportunities Market Analysis

    Explore 13 office space for sale in Bluffton, SC, showcased through 12 active listings on our real estate platform. These investment opportunities span a total of 0 square feet of properties for sale, with an estimated market value of $1,492,349.

    Prices for office space in Bluffton, SC start at $0.00, averaging $114,796, and reaching up to $593,450 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you have the most current data.

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    Browse Office space for Sale Near Bluffton, SC

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    Most Searched ZIP Codes in Bluffton, SC

    • 29910
    • 29909

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