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    Poplar Bluff, MO Office Space for Sale

    6 results
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    Versatile Commercial Building on Highway
    $419,000
    8,000 SF

    Versatile Commercial Building on Highway

    2323 Cheshire Blvd, Poplar Bluff, MO 63901

    8,000 sq ft building on high-traffic Highway 53.

    • High‑visibility location on high‑traffic Highway 53.
    • Versatile 8,000 sq ft building suitable for various commercial uses (offices, retail, sporting goods, mixed‑use).
    • Spacious parking lot to accommodate high customer volume.
    • Conveniently located near industrial park, shopping centers, and retail businesses.
    • Tall ceilings and large display windows.
    Updated: Dec 16, 2025
    View details
    Westwood Blvd Commercial Opportunity
    $599,500
    5,280 SF

    Westwood Blvd Commercial Opportunity

    2016 N Westwood Blvd, Poplar Bluff, MO 63901

    Prime commercial building on main thoroughfare with income potential.

    • Prime commercial location on Westwood Blvd with high visibility and traffic.
    • 5,280 sq ft +/- building with ample on‑site parking.
    • Existing lease with reputable medical tenant generating $3,322/month income.
    • Second unit (up to 2,640 sq ft +/-) available for lease or owner occupancy.
    • Attractive lease rate of $10/sq ft for the available unit.
    Updated: Dec 1, 2025
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    Versatile Commercial Space in Poplar Bluff
    $299,900
    3,475 SF

    Versatile Commercial Space in Poplar Bluff

    High-traffic location with remodeled space suitable for various business ventures.

    1025 S Westwood Blvd, Poplar Bluff, MO 63901
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    Poplar Bluff Commercial Building For Sale
    Pending
    $115,000
    3,000 SF

    Poplar Bluff Commercial Building For Sale

    Commercial building on Business Hwy 60, suitable for multiple uses.

    926 W Pine St, Poplar Bluff, MO 63901
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    Poplar Bluff Commercial Building For Sale
    $950,000
    6,500 SF

    Poplar Bluff Commercial Building For Sale

    6,500 sq ft building on 1.74 acres in Poplar Bluff.

    1026 Highway 67 S, Poplar Bluff, MO 63901
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    Renovated Commercial Space, Poplar Bluff
    $84,900
    975 SF

    Renovated Commercial Space, Poplar Bluff

    Renovated mixed-use space with high visibility, move-in ready.

    1614 S Broadway St, Poplar Bluff, MO 63901
    View details
    Based on your search, we've compiled 10 Potential Opportunities for your consideration. Besides 6 Active listings in Poplar Bluff, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Remodeled Office Building and Land
    $75,000
    1,320 SF

    Remodeled Office Building and Land

    Recently remodeled office building with land, ready for immediate occupancy.

    107 W 4Th St, Rector, AR 72461
    View details
    Downtown Rector Commercial Gem
    $89,000
    6,098 SF

    Downtown Rector Commercial Gem

    Mixed-use building, 6,098 sq ft

    418 Main St, Rector, AR 72461
    View details
    Updated Office Space in Paragould
    $85,000
    780 SF

    Updated Office Space in Paragould

    Charming, updated office space suitable for various professional uses.

    303 S 4Th Ave, Paragould, AR 72450
    View details
    Downtown Paragould Building and Land
    $255,000
    4,200 SF

    Downtown Paragould Building and Land

    Unique 4200 SF building in revitalized downtown Paragould.

    310 S Pruett St, Paragould, AR 72450
    View details

    Poplar Bluff, MO Office Space Investment Opportunities Market Analysis

    Explore 6 office space for sale in Poplar Bluff, MO, showcased through 6 active listings on our real estate platform. These investment opportunities span a total of 141,444 square feet of properties for sale, with an estimated market value of $2,353,300.

    Prices for office space in Poplar Bluff, MO start at $84,900, averaging $470,660, and reaching up to $950,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you have the most current data.

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