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Anderson County, SC Office Space for Lease

7 results
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Downtown Anderson Commercial Space Available
$1,350 / Mo
2,614 SF

Downtown Anderson Commercial Space Available

122 W Whitner St, Anderson, SC 29624

Versatile 1,300 SF space in historic downtown Anderson.

  • Prime location in historic downtown Anderson, across from the Anderson County Courthouse.
  • Versatile 1,300 square‑foot upper‑level space suitable for office, retail, or studio.
  • Adjacent to the City Parking Garage with ample street parking available.
  • Wood flooring throughout.
  • Adaptable floor plan.
Updated: Jan 15
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Class A Office Space
$3,400 / Mo

Class A Office Space

2315 N Main St, Anderson, SC 29621

Professional office suite for rent in Anderson, SC.

  • Prime Main Street location ideal for high‑visibility professional business.
  • Class A office building with included maintenance, electric, and water.
  • Versatile 2,800 sq ft suite suitable for medical or professional use.
  • Functional layout with five private offices, open floor plan, two restrooms, and a kitchen area.
  • Includes a welcoming reception area and large parking space.
Updated: Dec 9, 2025
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Downtown Anderson Retail Space
$10 SF/Yr
5,300 SF

Downtown Anderson Retail Space

Iconic 5,300 sqft space, prime location.

110 Greenville St, Anderson, SC 29621
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Office Space on Hwy 81
$15 SF/Yr
2,683 SF

Office Space on Hwy 81

Office space for lease near downtown Anderson and Anderson University.

1704 E Greenville St, Anderson, SC 29621
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Updated Office Space For Rent
$1,000 / Mo
840 SF

Updated Office Space For Rent

Recently updated office space suitable for various professional services.

69 Main St, Pelzer, SC 29669
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Office Space with Recent Upgrades
$5,000 / Mo
4,200 SF

Office Space with Recent Upgrades

Office space featuring new exterior paint and resurfaced parking lot.

120 E West Pkwy, Anderson, SC 29621
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Professional Office Space Available
Contact for pricing
3,000 SF

Professional Office Space Available

Well-maintained office park near US 178/N. Main St.

341 E Beltline Blvd, Anderson, SC 29621
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Based on your search, we've compiled 15 Potential Opportunities for your consideration. Besides 7 Active listings in Anderson County, SC, we suggest exploring alternatives. Similar 8 Properties for Sales.

Explore Similar Spaces for Sale in Anderson County, SC

Consider Similar Space for Sale. We found 8 Spaces in Nearby Locations matching your search parameters.

Versatile Mixed-Use Commercial Property
$750,000
0.48 Acres

Versatile Mixed-Use Commercial Property

Over 5,000 sq ft commercial property with residential area.

4327 Old Mill Rd, Anderson, SC 29623
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Move-In Ready Office Suite
$195,000

Move-In Ready Office Suite

Professional office suite in excellent condition near hospital.

400 N Fant St, Anderson, SC 29621
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Belton Commercial Building with Warehouse
$595,000
2.00 Acres

Belton Commercial Building with Warehouse

5,000 SF commercial building with office and warehouse space.

3361 Highway 29 N, Belton, SC 29627
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Belton Commercial Building on Two Acres
$595,000
5,000 SF

Belton Commercial Building on Two Acres

5,000 SF commercial building with office and warehouse space.

3361 Highway 29 N, Belton, SC 29697
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Anderson Automotive Garage with Living Space
$485,000
4,290 SF

Anderson Automotive Garage with Living Space

Automotive garage with living space in thriving Anderson, South Carolina.

609 Fair St, Anderson, SC 29625
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Williamston Commercial Opportunity For Sale
$279,900
0.47 Acres

Williamston Commercial Opportunity For Sale

Commercial building with rental potential in high-traffic Williamston, SC.

203 N Hamilton St, Williamston, SC 29697
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Office Space with Garage Bays
$429,900

Office Space with Garage Bays

Two-room office with three-bay garage near Highway 76.

103 Welpine Rd, Pendleton, SC 29670
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Modernized Income-Generating Commercial Property
$849,000

Modernized Income-Generating Commercial Property

9,500 sq ft building, fully leased, high-traffic location.

516 Pearman Dairy Rd, Anderson, SC 29625
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Anderson County, SC Office space Leasing Opportunities Market Analysis

Explore Office space leasing options in Anderson County, SC with 15 listings featured on our commercial real estate exchange. The current inventory includes 681,130,300 square feet of properties with an estimated lease value of $61 SF/Yr.

Estimated lease rates for Office space in Anderson County, SC begin at $6 SF/Yr, with an average of $12 SF/Yr and extend to $15 SF/Yr.
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