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    Saint Charles, MO Office Units for Lease

    15 results
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    Move-in Ready Office Space
    $500 / Mo

    Move-in Ready Office Space

    1480 Woodstone Dr, Saint Charles, MO 63304

    Full service office space with modern amenities included in rent.

    • All‑inclusive rent: Includes heat, electricity, trash, Wi‑Fi, kitchenette, and conference room use.
    • Move‑in ready office with recent renovations: new carpet, paint, lighting, interior and exterior updates.
    • Convenient location: Ample parking and easy access to Hwy 364 and 94.
    • Corner unit on the 1st floor with large windows providing natural light.
    • Access to atrium space with tables and outdoor seating.
    Updated: Dec 16, 2025
    View details
    Remodeled Office Space Near I-70
    $900 / Mo
    449 SF

    Remodeled Office Space Near I-70

    1600 Boones Lick Rd, Saint Charles, MO 63301

    Recently remodeled office suites for lease near I-70 in St. Charles.

    • Recently remodeled office space.
    • Convenient location near I‑70, between First Capitol and Convention Center exits.
    • Full‑service lease includes taxes, insurance, common area maintenance, and utilities.
    • Option to lease individual suites or combine for a larger space.
    • Each suite includes a large work/reception area with a built‑in kitchenette.
    Updated: Oct 10, 2025
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    Remodeled Office Space For Rent
    $950 / Mo
    520 SF

    Remodeled Office Space For Rent

    Recently remodeled office space for lease near I-70 in St. Charles.

    1600 Boones Lick Rd, Saint Charles, MO 63301
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    Remodeled Office Space Near I-70
    $1,750 / Mo
    1,064 SF

    Remodeled Office Space Near I-70

    Recently remodeled office suites for lease near I-70 in St. Charles.

    1600 Boones Lick Rd, Saint Charles, MO 63301
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    St Charles Lower-Level Office Space
    $700 / Mo
    30,492 SF

    St Charles Lower-Level Office Space

    660 SF office space with utilities and Wi-Fi included.

    1514 Caulks Hill Rd, Saint Charles, MO 63304
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    Historic Building Office Suites Available
    $14 SF/Yr
    1,961 SF

    Historic Building Office Suites Available

    Well-maintained office suites in historic building near courthouse.

    300 N Main St, Saint Charles, MO 63301
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    Retail and Office Space Available
    $30 SF/Yr
    1,577 SF

    Retail and Office Space Available

    Retail and office spaces for lease in Saint Charles, MO.

    340 N Main St, Saint Charles, MO 63301
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    Westgate 200 Available For Lease
    $5 SF/Yr

    Westgate 200 Available For Lease

    86,800 SF divisible space with office and showroom.

    3817-3841 Millstone Pkwy, Saint Charles, MO 63301
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    Office Space Near Highway
    Contact for pricing
    967 SF

    Office Space Near Highway

    Office space with excellent highway exposure and convenient location.

    2440 Executive Dr, Saint Charles, MO 63303
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    Office Space with Ample Parking
    Contact for pricing
    1,685 SF

    Office Space with Ample Parking

    Office space for rent with easy highway access and parking.

    205 N 5Th St, Saint Charles, MO 63301
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    Professional Office Space Available
    Contact for pricing
    598 SF

    Professional Office Space Available

    Office space with excellent highway exposure and convenient location.

    2480 Executive Dr, Saint Charles, MO 63303
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    St. Charles Retail/Office Space
    $22 SF/Yr
    31,716 SF

    St. Charles Retail/Office Space

    Retail and office spaces available in high-traffic St. Charles location.

    3910-3930 South Old Highway 94, Saint Charles, MO 63304
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    Stand Alone Office For Rent
    Contact for pricing
    1,377 SF

    Stand Alone Office For Rent

    1,377 SF stand-alone office space remodeled in 2023.

    1518 Caulks Hill Rd, Saint Charles, MO 63304
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    Fountainview Plaza: St. Charles Office Space
    $16 SF/Yr
    29,742 SF

    Fountainview Plaza: St. Charles Office Space

    Prime St. Charles location; 2,602 SF available.

    2633 Muegge Rd, Saint Charles, MO 63303
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    201 Main St
    $15 SF/Yr
    10,950 SF

    201 Main St

    Coworking space • 10,950 SF

    201 Main St, Saint Charles, MO 63301
    View details
    Based on your search, we've compiled 20 Potential Opportunities for your consideration. Besides 15 Active listings in Saint Charles, MO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 1 Properties for Sales.

    Explore Office Units for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Office Building with Available Spaces
    Contact for pricing
    2,500 SF

    Office Building with Available Spaces

    Office building for lease in high-traffic area with parking.

    510-514 Jungermann Rd, St Peters, MO 63376
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    St. Peters Office Space Available
    Contact for pricing
    2,000 SF

    St. Peters Office Space Available

    Office space for rent in established St. Peters office development.

    1270 Jungermann Rd, St Peters, MO 63376
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    Earth City Office Space Available
    $12 SF/Yr
    8,000 SF

    Earth City Office Space Available

    Office space featuring private offices, conference rooms, and ample parking.

    4101 Rider Trl N, Earth City, MO
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    Class A Office Space Available
    Contact for pricing
    18,434 SF

    Class A Office Space Available

    Plug & play office space for sublease through March 2028.

    3300 Rider Trl S, Earth City, MO
    View details

    Explore Similar Spaces for Sale in Saint Charles, MO

    Consider Similar Space for Sale. We found 1 Spaces in Nearby Locations matching your search parameters.

    Main Street Mixed-Use Building
    $750,000

    Main Street Mixed-Use Building

    Multi-story building with restaurant, retail, office, and residential potential.

    138 N Main St, Saint Charles, MO 63301
    View details

    Saint Charles, MO Office Units Leasing Opportunities Market Analysis

    Explore Office Units leasing options in Saint Charles, MO with 16 listings featured on our commercial real estate exchange. The current inventory includes 3,396,765,240 square feet of properties with an estimated lease value of $162 SF/Yr.

    Estimated lease rates for Office Units in Saint Charles, MO begin at $14 SF/Yr, with an average of $20 SF/Yr and extend to $30 SF/Yr.
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    Popular Searches in Saint Charles, MO

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    Most Searched ZIP Codes in Saint Charles, MO

    • 63301
    • 63303
    • 63304

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