Des Moines, IA Office space for Rent & Lease

$20 SF/Yr

1,800 SF

Modern Turn-Key Office Space

323 E Walnut St, Des Moines, IA 50309

Turn-key office space with ample parking near I-235.

Turn‑key, modern office space ready for your business.
Ample on‑site parking for employees and clients.
Located at a lighted intersection.
Close‑proximity to I‑235.
Access via East 6th Street.

Updated: Sep 25, 2025

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$24 SF/Yr

4,182 SF

Class A+ Office Space

110 E Court Ave, Des Moines, IA 50309

Premier office location with river views and modern amenities.

Class A+ office building with stunning Riverwalk, Des Moines River, and Capitol views.
Prime East Village location near neighborhood amenities and the Court Avenue Entertainment District.
Onsite fitness center featuring top‑of‑the‑line equipment and private bathrooms.
Brand‑new Class A+ lobby and enhanced artwork throughout common areas.
Benefit from all‑new chillers, air‑handler, elevators, 4,000 amp electrical service, and roof.

Updated: Jul 8, 2025

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$20 SF/Yr

92,296 SF

Court Avenue Office Space

Des Moines CBD, IA: Classic office space available.

100 Court Ave, Des Moines, IA 50309

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$18 SF/Yr

2,296 SF

Des Moines Restaurant/Office Space

Prime Des Moines location, 2,296 sq ft available.

11th & Martin Luther King Jr Pkwy, Des Moines, IA 50309

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$8 SF/Yr

15,518 SF

699 Walnut St

Office space • 15,518 SF

699 Walnut St, Des Moines, IA 50309

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33,792 SF

Des Moines Creative Office Space

Modern Office Suites in Des Moines' Market District

118 4Th St, Des Moines, IA 50309

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20,000 SF

Des Moines Office Building For Lease

20,000 SF Office, Prime Location

113 8Th St, Des Moines, IA 50309

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Locust Plaza: Des Moines Creative Office

$17 SF/Yr

11,272 SF

Locust Plaza: Des Moines Creative Office

Historic Des Moines office, prime location, ample parking.

1420 Locust St, Des Moines, IA 50309

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$10 SF/Yr

51,058 SF

Des Moines Executive Office Suites

Class A Office Space, Des Moines, IA

2600 Grand Ave, Des Moines, IA 50312

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$27 SF/Yr

14,401 SF

Des Moines Creative Office Sublease

1,215 SF Creative Office Space Available

112 4Th St, Des Moines, IA 50309

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8,000 SF

Divisible Warehouse Space Available

Up to 145,000 RSF available with shared access.

1901 Bell Ave, Des Moines, IA 50315

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$12 SF/Yr

2,646 SF

Des Moines Office Space Available

Office units for rent in Des Moines, Iowa.

2501 Grand Ave, Des Moines, IA 50312

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$12 SF/Yr

7,500 SF

Des Moines Office Space Available

7,500 SF office space near downtown and I-80.

100 E Euclid Ave, Des Moines, IA 50313

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$27 SF/Yr

1,215 SF

Modern Mixed-Use Converted Warehouse

Mixed-use building featuring office, brewery, and apartments.

112 SE 4Th St, Des Moines, IA 50309

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$11 SF/Yr

8,134 SF

Des Moines Office Space Available

Office space for rent with on-site parking and storage.

303 Watson Powell Jr Way, Des Moines, IA 50309

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120,643 SF

Des Moines Office and Retail

Office and retail space in established Ruan Center building.

666 Grand Ave, Des Moines, IA 50309

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$11 SF/Yr

2,400 SF

Des Moines Office Space Available

Office space for lease near downtown Des Moines and Interstate.

300 E Locust St, Des Moines, IA 50309

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$11 SF/Yr

20,280 SF

Des Moines Office Space Available

Office building with health-conscious features, skywalk access, and rooftop patio.

611 5Th Ave, Des Moines, IA 50309

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$11 SF/Yr

2,576 SF

Des Moines Office Space Available

Office space with skywalk access, natural light, and parking nearby.

420 Watson Powell Jr Way, Des Moines, IA 50309

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$20 SF/Yr

1,700 SF

Des Moines Office Space Available

Office space available for lease in Des Moines, Iowa.

405 6Th Ave, Des Moines, IA 50309

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15,750 SF

Des Moines Office Space Available

Office space available for rent in Des Moines, Iowa.

520 Walnut St, Des Moines, IA 50309

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$1,450,000

12,747 SF

Des Moines Flex/Office Space

Available flex and office space in Des Moines.

101 Sheridan Ave, Des Moines, IA 50313

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$11 SF/Yr

25,088 SF

Visible Office Space on Merle Hay

Highly visible office space with utilities included on Merle Hay.

4725 Merle Hay Rd, Des Moines, IA 50322

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$650 / Mo

5,198 SF

Restored Historic Building Office Space

Flexible office space in a beautifully restored historic building.

1163 24Th St, Des Moines, IA 50311

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Des Moines, IA Office space Leasing Opportunities Market Analysis

Explore Office space leasing options in Des Moines, IA with 56 listings featured on our commercial real estate exchange. The current inventory includes 15,017,484,240 square feet of properties with an estimated lease value of $507 /Mo.

Estimated lease rates for Office space in Des Moines, IA begin at $1.50 SF/Yr, with an average of $15 SF/Yr and extend to $27 SF/Yr.

Des Moines, IA Office Space for Lease

Modern Turn-Key Office Space

Turn-key office space with ample parking near I-235.

Class A+ Office Space

Premier office location with river views and modern amenities.

Court Avenue Office Space

Des Moines Restaurant/Office Space

699 Walnut St

Des Moines Creative Office Space

Des Moines Office Building For Lease

Locust Plaza: Des Moines Creative Office

Des Moines Executive Office Suites

Des Moines Creative Office Sublease

Divisible Warehouse Space Available

Des Moines Office Space Available

Des Moines Office Space Available

Modern Mixed-Use Converted Warehouse

Des Moines Office Space Available

Des Moines Office and Retail

Des Moines Office Space Available

Des Moines Office Space Available

Des Moines Office Space Available

Des Moines Office Space Available

Des Moines Office Space Available

Des Moines Flex/Office Space

Visible Office Space on Merle Hay

Restored Historic Building Office Space

Des Moines, IA Office space Leasing Opportunities Market Analysis

Browse Office space for Lease Near Des Moines, IA

Popular Searches in Des Moines, IA

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Des Moines, IA Office Space for Lease

Modern Turn-Key Office Space

Turn-key office space with ample parking near I-235.

Class A+ Office Space

Premier office location with river views and modern amenities.

Court Avenue Office Space

Des Moines Restaurant/Office Space

699 Walnut St

Des Moines Creative Office Space

Des Moines Office Building For Lease

Locust Plaza: Des Moines Creative Office

Des Moines Executive Office Suites

Des Moines Creative Office Sublease

Divisible Warehouse Space Available

Des Moines Office Space Available

Des Moines Office Space Available

Modern Mixed-Use Converted Warehouse

Des Moines Office Space Available

Des Moines Office and Retail

Des Moines Office Space Available

Des Moines Office Space Available

Des Moines Office Space Available

Des Moines Office Space Available

Des Moines Office Space Available

Des Moines Flex/Office Space

Visible Office Space on Merle Hay

Restored Historic Building Office Space

Des Moines, IA Office space Leasing Opportunities Market Analysis

Browse Office space for Lease Near Des Moines, IA

Popular Searches in Des Moines, IA

Popular Categories

Most Searched ZIP Codes in Des Moines, IA

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