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    South Setauket, NY Office Spaces for Sale

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    East Setauket, NY Stonybrook, NY Lake Grove, NY
    Centereach Office Space For Sale
    $699,000
    0.30 Acres
    Centereach Office Space For Sale

    2539 Middle Country Road, Centereach, NY 11720

    Office spaces in high-traffic Centereach location on Middle Country Road.
    • High‑traffic location on Middle Country Road (Route 25)
    • Multiple office spaces suitable for end‑users or investors
    • Central air conditioning
    • Baseboard heating
    • Basement included
    Updated: Oct 30, 2025
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    Established Dental Office For Sale
    Contact for pricing
    3,549 SF
    Established Dental Office For Sale

    1 Mark Tree Road, Centereach, NY 11720

    Long-term dental tenant in medical corridor.
    • Stable dental office with long‑term tenant retention potential.
    • 10‑year initial lease term (expires March 19, 2033).
    • Located in a well‑established medical corridor.
    • Resilient tenant profile in a healthcare‑driven submarket.
    • Strong visibility and reliable patient traffic.
    Updated: Mar 25
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    Centereach Retail and Office Space
    Contact for pricing
    5,600 SF
    Centereach Retail and Office Space

    5,600 SqFt retail and office space available for sale.

    2101 Middle Country Rd, Centereach, NY 11720

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    Based on your search, we've compiled 33 Potential Opportunities for your consideration. Besides 3 Active listings in South Setauket, NY, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 22 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Turnkey Ground-Floor Medical Office Suite
    $999,995
    2,500 SF
    Turnkey Ground-Floor Medical Office Suite

    Ground-floor, turnkey office suite previously used by a medical practitioner, with possible expansion options.

    103-8 Nesconset Hwy, East Setauket, NY 11733

    View details
    Medical Office Building For Sale
    $3,150,000
    7,000 SF
    Medical Office Building For Sale

    Medical office building with tenant in place, near LIE.

    243 Boyle Rd, Selden, NY

    View details
    Office Building on Corner Lot
    Contact for pricing
    10,000 SF
    Office Building on Corner Lot

    10,000 Sq. Ft. office building on 2.19 acres.

    761-765 Middle Country Rd, Selden, NY

    View details
    East Setauket Corner Office Unit
    Contact for pricing
    6,800 SF
    East Setauket Corner Office Unit

    Corner office unit in Stonybrook Technology/Medical Park.

    2-21 Technology Dr, East Setauket, NY

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Land in Port Jefferson
    $3,250,000
    4.10 Acres
    Prime Land in Port Jefferson

    4.1 acre commercial land in revitalizing Port Jefferson Station.

    527/529 Route 112, Port Jefferson Station, NY 11776

    View details
    Rocky Point Commercial Lot
    $390,000
    0.41 Acres
    Rocky Point Commercial Lot

    J-2 zoned commercial lot in Rocky Point, NY.

    N Country Roads, Rocky Point, NY

    View details
    Commercial Land Near Montauk Highway
    $699,000
    0.50 Acres
    Commercial Land Near Montauk Highway

    Vacant commercial lot near Montauk Hwy, Shirley, NY.

    V/L Versa Place, Shirley, NY 11967

    View details
    Commercial Land Near Montauk Highway
    $699,000
    0.50 Acres
    Commercial Land Near Montauk Highway

    Prime commercial lot near shopping, zoned J6, approved for building.

    V/L Versa Place, Shirley, NY 11967

    View details

    Off-Market Properties in South Setauket, NY

    Consider similar Off-Market properties in South Setauket, NY. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    1523 Middle Country Rd
    PROFESSIONAL BUILDING
    Lot: 0.09 Acres
    Estimated value
    $550,000

    1523 Middle Country Rd, Centereach, NY 11720-3513

    View details
    2450 Middle Country Rd
    PROFESSIONAL BUILDING
    Lot: 0.45 Acres

    2450 Middle Country Rd, Centereach, NY 11720-3548

    View details
    2112 Middle Country Rd
    PROFESSIONAL BUILDING
    Estimated value
    $9,000,000

    2112 Middle Country Rd, Centereach, NY 11720-3519

    View details
    18 Eastwood Blvd
    PROFESSIONAL BUILDING
    Lot: 0.12 Acres
    Value Estimation by Request

    18 Eastwood Blvd, Centereach, NY 11720-2735

    View details
    99 Mark Tree Rd
    OFFICE BUILDING
    Lot: 0.59 Acres
    Value Estimation by Request

    99 Mark Tree Rd, Centereach, NY 11720-2276

    View details
    26 Eastwood Blvd
    PROFESSIONAL BUILDING
    Lot: 0.22 Acres
    Value Estimation by Request

    26 Eastwood Blvd, Centereach, NY 11720-2735

    View details
    2297 Middle Country Rd
    OFFICE BUILDING
    Lot: 0.25 Acres
    Value Estimation by Request

    2297 Middle Country Rd, Centereach, NY 11720-3666

    View details
    7 Mark Tree Rd
    PROFESSIONAL BUILDING
    Lot: 0.28 Acres
    Value Estimation by Request

    7 Mark Tree Rd, Centereach, NY 11720-2221

    View details
    1919 Middle Country Rd
    OFFICE BUILDING
    Lot: 0.63 Acres
    Value Estimation by Request

    1919 Middle Country Rd, Centereach, NY 11720-5600

    View details
    1797 Middle Country Rd
    PROFESSIONAL BUILDING
    Lot: 0.54 Acres
    Value Estimation by Request

    1797 Middle Country Rd, Centereach, NY 11720-5701

    View details
    7 Rosemary Ln
    PROFESSIONAL BUILDING
    Lot: 0.20 Acres
    Value Estimation by Request

    7 Rosemary Ln, Centereach, NY 11720-4440

    View details
    1820 Middle Country Rd
    PROFESSIONAL BUILDING
    Lot: 1.30 Acres
    Value Estimation by Request

    1820 Middle Country Rd, Centereach, NY 11720-3675

    View details
    1787 Middle Country Rd
    PROFESSIONAL BUILDING
    Lot: 1.46 Acres

    1787 Middle Country Rd, Centereach, NY 11720-3507

    View details
    9 Smith St
    OFFICE BUILDING
    Lot: 0.21 Acres
    Value Estimation by Request

    9 Smith St, Centereach, NY 11720-3855

    View details
    2535 Middle Country Rd
    PROFESSIONAL BUILDING
    Lot: 0.25 Acres
    Value Estimation by Request

    2535 Middle Country Rd, Centereach, NY 11720-5400

    View details
    1 Mark Tree Rd
    PROFESSIONAL BUILDING
    Lot: 0.25 Acres

    1 Mark Tree Rd, Centereach, NY 11720-2279

    View details
    141 Mark Tree Rd
    PROFESSIONAL BUILDING
    Lot: 0.33 Acres
    Value Estimation by Request

    141 Mark Tree Rd, Centereach, NY 11720-2221

    View details
    Middle Country Rd
    OFFICE BUILDING
    Lot: 0.25 Acres
    Value Estimation by Request

    Middle Country Rd, Centereach, NY 11720

    View details
    2539 Middle Country Rd
    PROFESSIONAL BUILDING
    Lot: 0.30 Acres

    2539 Middle Country Rd, Centereach, NY 11720-3551

    View details
    Wireless Rd
    MEDICAL CLINIC
    Lot: 49.83 Acres
    Value Estimation by Request

    Wireless Rd, Centereach, NY 11720

    View details
    2566 Middle Country Rd
    PROFESSIONAL BUILDING
    Lot: 0.50 Acres
    Value Estimation by Request

    2566 Middle Country Rd, Centereach, NY 11720-3525

    View details

    South Setauket, NY Office Spaces Investment Opportunities Market Analysis

    Explore 25 office spaces for sale in South Setauket, NY, showcased through 3 active listings on our real estate platform. These investment opportunities span a total of 9,149 square feet of properties for sale, with an estimated market value of $699,000.

    Sale prices for office spaces in South Setauket, NY start at $0.00, averaging $233,000, and reaching up to $699,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

    List
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    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Office Units 5
    Medical Office Space 3
    Office buildings 1
    Serviced offices 1

    Demographics Overview

    Population 29K
    Population Growth (5Y) +0.4%
    Median Household Income $128,015
    College Educated 53.2%

    Listings Trend

    New vs delisted commercial listings in Suffolk County

    New Delisted

    Total CRE Inventory on Market (SF)

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